Resource Butanediol megathread

[311]

I don't post much on here- but I do read a lotttttttttttt. I read this thread and wanted to give some input. I'm gay and from Canada. In the gay community where I live GHB is very easy to get a hold of. Many gays who party purposely take it in very low quantities in order to get that very drunk feeling without having to drink tons. I use to purposely take GHB (about a small water bottle cap full) before going out in order to feel drunk. I use to take a bit before clubbing, then a bit more in my drink at the club and slowly sip my drink, because it would only last about 1-2 hrs that drunk feeling. It intensifies the effect of alcohol like crazy. The thing is that the amount needed to attain that drunken high, and over dosing, is very minimal. About three times i took about 1-2 capfulls too much and ended up passing out in the club, the bouncers wanted to call an ambulance but my friends got me home. I was knocked out with no memory. I was in the deepest "sleep" and couldn't wake up no matter what my friends tried. I eventually woke up about 5 hours after the accidental "overdose". When I would mix it with alcohol (again the main purpose for me back then was just to get a very drunk feeling) i would feel so nauseas, but rarely threw up. Sorry for writing so much , the point I wanted to make was just to give a point of view on my experiences on GHB. Also, the taste is definitely horrible. It's veryyyy salty. Sorry to use this analogy, but it taste like cum with 20x more added salt. Real GHB will not freeze. My best friend was a drug dealer so he'd let me know how other dealers would cut their GHB liquid , and the way to tell was of it froze or not. The consistency is not watery- it's like a syrop consistency. Anyways again sorry for writing so much just wanted to provide my experiences!

So its lethal in huge quantities.

 

[couldntthinkofaname]

I don't post much on here- but I do read a lotttttttttttt. I read this thread and wanted to give some input. I'm gay and from Canada. In the gay community where I live GHB is very easy to get a hold of. Many gays who party purposely take it in very low quantities in order to get that very drunk feeling without having to drink tons. I use to purposely take GHB (about a small water bottle cap full) before going out in order to feel drunk. I use to take a bit before clubbing, then a bit more in my drink at the club and slowly sip my drink, because it would only last about 1-2 hrs that drunk feeling. It intensifies the effect of alcohol like crazy. The thing is that the amount needed to attain that drunken high, and over dosing, is very minimal. About three times i took about 1-2 capfulls too much and ended up passing out in the club, the bouncers wanted to call an ambulance but my friends got me home. I was knocked out with no memory. I was in the deepest "sleep" and couldn't wake up no matter what my friends tried. I eventually woke up about 5 hours after the accidental "overdose". When I would mix it with alcohol (again the main purpose for me back then was just to get a very drunk feeling) i would feel so nauseas, but rarely threw up. Sorry for writing so much , the point I wanted to make was just to give a point of view on my experiences on GHB. Also, the taste is definitely horrible. It's veryyyy salty. Sorry to use this analogy, but it taste like cum with 20x more added salt. Real GHB will not freeze. My best friend was a drug dealer so he'd let me know how other dealers would cut their GHB liquid , and the way to tell was of it froze or not. The consistency is not watery- it's like a syrop consistency. Anyways again sorry for writing so much just wanted to provide my experiences!

what did you take?

ghb or 1,4-butanediol ?

 

[311]

That´s a good way of putting it. Since docs really messed me up I´m not that willing to trust anecdotes on the web.
I´d have questions like : where are those GHB receptors, what do they really do, in what quantities ? To what extent is there cross tolerance with other sedatives ?

Bro sedatives in different classes dont have cross tolerances in most cases. Opiates don't have cross tolerances with benzos or barbituates. Benzos and barbituates have some cross tolerance but if you were to take 12 grams of nembutal haven been on 20mg of valium you will die. GHB does not have a cross tolerance with benzos or barbituates. GHB is an entirely different receptor. If you're actually curious, research where the receptors are, but since the ghb receptor is a novel receptor I doubt you will find anything. Tbh if you take 20mg of valium equivalent of benzos you're still going to die from 1,4 b.

 

[Arak]

https://en.m.wikipedia.org/wiki/GHB_receptor

'The function of the GHB receptor appears to be quite different from that of the GABAB receptor. It shares no sequence homology with GABAB, and administration of mixed GHB/GABAB receptor agonists along with a selective GABAB antagonist or selective agonists for the GHB receptor which are not agonists at GABAB, do not produce a sedative effect, instead causing a stimulant effect followed by convulsions at higher doses, thought to be mediated through increased Na+/K+ current and increased release of dopamine and glutamate.[4][5][6][7][8][9]'

One could theorize that if for some reason this substance effects GABAB receptors in a way that's not sufficient, it simply wouldn't work. I can only speculate about what that would mean for me.

 

[Arak]

@TiredHorse ,

I doubt if I could. It's science. In a nutshell: according to the wiki article GHB would only 'work' for our purpose if it can act effectively/normally at the GABAB receptors. GABAB: https://en.m.wikipedia.org/wiki/GABAB_receptor Maybe not completely correct, but the neurotransmitter GABA acts on both GABAA and GABAB receptors.

Hypothetically, if one has taken a high dose of baclofen (acts on GABAB), daily, long term it may have altered those receptors.

What happens if your brain has been too messed up ? I don't know.

 

[TiredHorse]

So let me see if I understand. Translated into Dunce:

Benzos act on GABA-A receptors.
GHB/1,4B acts on GABA-A receptors.

Therefore, a history of heavy benzo use/tolerance might influence the efficacy of GHB/1,4B?

Is that correct?

 

[311]

@311,

See post #459. I'm out of this discussion with you.

Bro it puts you in a coma. Its literally used for general anesthesia. But I'm asking if your currently taking benzos.

 

[TiredHorse]

Am I crazy, what happened to my well thought out long informational post on this?

This one?: https://sanctioned-suicide.net/threads/mega-thread-butanediol.9644/page-5#post-171528

 

[BellaKAT]

i'm confused... 1,4 butanediol is not a benzo. so there should be no cross tolerance right?

also according to https://www.aafp.org/afp/2000/1201/p2478.html and lots of other sources - ghb is a cns depressant, and combined with with other depressants such as benzos it would punctuate the effects. so giving them to help with ghb induced seizures seems dicey. ?

i'm not a scientist / psychiatrist or anything and idk if this is relevant but i know all depressants ( alcohol / benzos /opiates etc) all by increasing activity of gamma-aminobutyric acid (GABA). doesn't mean there is cross tolerance between them.

 

[TiredHorse]

A re-post from @Stillnotsure, since it got a bit buried and it seems to again be relevant to the discussion:

"Ok, here's what I found....

1mL of 99.0-99.9 % 1,4 butanediol is equal to 1 gram of GHB the recreational drug. This is helpful because we can compare the effects of the 1,4 Butanediol to GHB. 1-2 grams of GHB is the standard dose users take for the euphoric and sedative effects. To overdose and cause death gets a bit trickier because of our individual bodies ability to break down the GHB. The same chemicals in our stomachs and blood (liver) that break down alcohol, also break down GHB.

The caveat! Many sites I found say it takes 5-10 grams of GHB to overdose, and any dose over 10 grams can be fatal. Since 1,4 butanediol has a few steps to take in the body to become GHB, it could take more than 5-10 mL to overdose or die!

The fix. Since 1,4 butanediol is broken down in the body by the same chemicals and enzymes that break down alcohol, mixing your 1,4 butanediol with alcohol has a drastically increased fatality rate because the body doesn't have enough chemicals and enzymes to break both down. In theory, you should need less 1,4 butanediol by pairing it with alcohol, but should stick to the highest purity rate available and at least 10 mL to be safe.

Now the mega downside. 1,4 butanediol is chemical and very bitter tasting. Those traits alone make a person nauseous and can cause vomiting. Real GHB tastes salty because it is a different chemical chain mixed with a salt chain. It's easier to drink real GHB. If you are going to use either to CTB you should mix it with alcohol. The best way to overcome the nausea and vomiting that are caused by GHB or 1,4 butanediol is by taking the full fatal dose of either quickly in one big swallow, not over time. That way you should fall asleep before your body has time to become nauseous.

To overcome the bodies natural response to the bitter chemical taste of 1,4 butanediol, you may have to consider the antiemetic regimen prescribed by A for Overdose on B."

 

[Stillnotsure]

This one?: https://sanctioned-suicide.net/threads/mega-thread-butanediol.9644/page-5#post-171528

Damn that's buried in there, haha yup.

i'm confused... 1,4 butanediol is not a benzo. so there should be no cross tolerance right?
buttttt according to https://www.aafp.org/afp/2000/1201/p2478.html and lots of other sources - ghb is a cns depressant, and combined with with other depressants such as benzos it would punctuate the effects. so giving them to help with ghb induced seizures seems dicey.
i'm not a scientist / psychiatrist or anything and idk if this is relevant but i know all depressants ( alcohol / benzos /opiates etc) all by increasing activity of gamma-aminobutyric acid (GABA). doesn't mean there is cross tolerance between them.

My understanding of it is that compound use of benzos, GHB, or alcohol compete for the same receptors in the CNS. They potentiate eachother, or increase the CNS depressing effects because they both depress the system in the same way. So, while you may have built up a tolerance to say, alcohol, requiring more to get the same effect, mixing CNS depressants actually helps you need less alcohol to get the same effects. There are more chemicals bouncing around for the receptors to respond to. Since there a limited number of receptors, what matters is that any CNS depressing chemical makes it to the receptor. Did I explain that clearly enough?

 

[311]

To simplify this thread. If you mix the 2oz with orange juice or take it straight, you will die. People murder others with this. People commit suicide with this and others just die from it. 60grams is a mega dose that will kill you

 

[BellaKAT]

Damn that's buried in there, haha yup.




My understanding of it is that compound use of benzos, GHB, or alcohol compete for the same receptors in the CNS. They potentiate eachother, or increase the CNS depressing effects because they both depress the system in the same way. So, while you may have built up a tolerance to say, alcohol, requiring more to get the same effect, mixing CNS depressants actually helps you need less alcohol to get the same effects. There are more chemicals bouncing around for the receptors to respond to. Since there a limited number of receptors, what matters is that any CNS depressing chemical makes it to the receptor. Did I explain that clearly enough?

yes i think youre just explaining more of/ better of what i'm trying to say. the point i'm trying make / ask is that tolerance to benzos in fact wouldnt make this method unviable. and using benzos with it would probably just enhance the depressive effects

To simplify this thread. If you mix the 2oz with orange juice or take it straight, you will die. People murder others with this. People commit suicide with this and others just die from it. 60grams is a mega dose that will kill you

where did you find solid evidence of this? I do believe it's possible i'm just wondering bc i think seeing that would make me more confident in using this method myself.

 

[311]

yes i think youre just explaining more of/ better of what i'm trying to say. the point i'm trying make / ask is that tolerance to benzos in fact wouldnt make this method unviable. and using benzos with it would probably just enhance the depressive effects




where did you find solid evidence of this? I do believe it's possible i'm just wondering bc i think seeing that would make me more confident in using this method myself.

over ten grams is considered a fatal dose. Ive seen it on wikipedia and psychonaut and ancedotal reports. 60grams is such a massive dose. youre cns will be overwhelmed. You will go into a coma and stop breathing. Im sure of it. If people can slip it in drinks and kill people or use it as poison to go on a serial killing spree, then 60 grams will surely kill you.

 

[GerMann]

"or take it straight" .... No! I do not belive a normal human can drink more than 10ml of pure 1.4D without puke. Mix it at least 10 x .

 

[Floraknife]

"or take it straight" .... No! I do not belive a normal human can drink more than 10ml of pure 1.4D without puke. Mix it at least 10 x .

What about mixing the 2oz with a strong screwdriver? You'd think the taste would be masked for the most part, no?

 

[purposeless]

I personally never tasted it but in an artical I read the taste is descripted as "chemical , rubbery and slightly pungent taste". I also heard from people drinking it straight up or people just mixing it with a small amount of alcohol to get high or something so seemingly the taste seem to be endurable. Though I can't say that for sure....

 

[Arak]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853692/

And as a reminder, statement of the mods post #1.

 

[Arak]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462042/

https://www.karger.com/article/fulltext/443173

https://www.who.int/medicines/areas/quality_safety/4.1GHBcritical_review.pdf

https://www.drugbank.ca/drugs/DB01440

It's understandable if you don't understand these links, you need to have a certain basic knowledge of science to make sense of it all. And then, even without a specific knowledge base as a background it's hard.
I recommend the WHO article. I did find these articles while I was looking for something else.

 

[311]

 

[311]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462042/

https://www.karger.com/article/fulltext/443173

https://www.who.int/medicines/areas/quality_safety/4.1GHBcritical_review.pdf

https://www.drugbank.ca/drugs/DB01440

It's understandable if you don't understand these links, you need to have a certain basic knowledge of science to make sense of it all. And then, even without a specific knowledge base as a background it's hard.
I recommend the WHO article. I did find these articles while I was looking for something else.

Good research man

 

[311]

I would reccomend anyone using this method to mix with alcohol

 

[TiredHorse]

My 1,4B arrived in today's mail: two 1oz glass bottles (so shelf-stable) with eyedroppers in a bubble-pack envelope.

Interestingly, the return address is from "Bryan Miller/Indiana Chemical LLC" and is out of "Apt 511" --which seems odd for an industrial address. I suspect we are not the only consumers purchasing 1,4B for a use other than as a plastic solvent, which bodes well for a discrete transaction.

It's currently about 40° here, so they are frozen solid, but once they thaw I'll do a taste-test and post what I find.

 

[kateandella]

Ive always wanted ghb to ctb since it puts you to sleep right away and its a very small amount of liquid. Like 2ml. But its hard to get BUT a prodrug of it that metabolizes into ghb and i guess is not that well known in the US but sold as de facto ghb in Australia and is purchasable on amazon. it carries no risk of incarceration and its reliably fatal. What do you think?

https://www.vice.com/en_us/article/qbxexv/dark-side-of-ghb-narcomania-003

This method is fairly complicated. Care should be taken upon using this method. Please do due diligence when choosing a method.

Thanks,

mod team

Created an account to ask about the mod note. Based on the discussion it seems as straightforward as taking N (antiemetic + alcohol + 2noz of 1, 4). What exactly is complicated?

 

[TiredHorse]

Created an account to ask about the mod note. Based on the discussion it seems as straightforward as taking N (antiemetic + alcohol + 2noz of 1, 4). What exactly is complicated?

The metabolism chemistry lends an element of complexity of the process, but I suspect the majority of the complexity is philosophical: the use of deliberate 1,4B OD is unproven in the application of suicide, so... caveat emptor.

any luck?

Still thawing; almost there. I'm not rushing the process --they're on the bookshelf near my woodstove-- so that I don't risk degrading the product. Each bottle currently has about half its volume as a loose stratum of small crystals. I can shake it up and make it into a sort of slurry. Once the crystals are dissolved and I'm sure the product is homogenous, I'll put a drop on my tongue and report back.

 

[Itstimeforpeace]

I picked mine up from my post office box today. Mine is the 8oz and it's in a plastic container. Mine was frozen too but it's all thawed out now.

It's scary having it at my fingertips. I'm trying so hard to get help and not use it.

 

[TiredHorse]

Okay, one drop on the tongue, and yes, it's nasty. Very chemical-y. Not salty; bitter. Oily texture. Bleah!

I'm thinking anti-emetics will be important.

Did I mention bleah?

BLEAH!

Oh lovely; the aftertaste stays nasty, too. And it climbs up into your nose.

(Bleah!)

I'm off to the kitchen to try and kill the aftertaste. Maybe maple syrup will help. I certainly hope something does.

I will report any interesting "recreational" effects, but as small a dose as I just took, I doubt I will experience anything entertaining. Certainly not anything worth that flavor experience.

(BLEAH!)

 

[TiredHorse]

I'm elaborating on it a bit over in the other 1,4B thread, but the short answer is that I don't know. It has the same aromatic pervasiveness as I have experienced with alcohol (I almost never drink alcohol), and so if it is simply a matter of overwhelming one flavor with another, mixing up a cocktail seems like a possible remedy.

It has an oilyness that I can still feel on my lips, though. That's not very pleasant. Of course if this were "for real," I probably wouldn't need to worry about that very long, would I?

 

[Jadon91]

For you which is the best source?

This?

https://www.ebay.de/itm/Butandiol-B...hash=item41d2ac83cf:m:mwCfMbuYYC_MXkq0u6-ubRg

Or this?
https://www.ebay.de/itm/200-ml-1-4-...m=391429324761&_trksid=p2056116.c100930.m5375

 

[RememberWhatUCameFor]

https://psychonautwiki.org/wiki/1,4-Butanediol