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keat6890

Member
Mar 6, 2025
14
I don't like to live, i wish i had never benn born, life is a shit and i loking for a way to kill myself. Could taking several antidepressants kill me ?
 
Comaa

Comaa

☆People might remember you, but only if youre dead
Jul 26, 2026
24
I don't like to live, i wish i had never benn born, life is a shit and i loking for a way to kill myself. Could taking several antidepressants kill me ?
Please don't attempt this method. It's explicitly deemed as a non-method that shouldn't be attempted, as it has a pitful success rate docummented, about only 0.5% to 14% depending on the type of an antidepressant if I recall correctly. I think it's even mentioned in one of the pinned megathreads on this forum. I'm really sorry you're feeling this way, and I really hope that you can find a solution that ultimately brings you release. But please, reconsider this method, as it has a really high chance of giving you a painful outcome that you probably, certainly don't need and don't wish upon yourself.
 
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RazzleDazzle

The void stares back.
Sep 16, 2021
324
The mechanism of how antidepressants work is not fatal, even in very high doses. Even high doses over a long period of time.

They just don't do anything that is fatal. They basically affect how your nervous system regulates neurotransmitters. But they don't completely override your nervous system, they more just provide a nudge in a certain direction.

SSRIs are telling the nervous system to be a little more chill about breaking down serotonin. If you took a high dose of an SSRI it'd be a little taxing on your liver and kidneys, and that's about it, because it takes some time for that change in serotonin regulation to happen. Taking high doses multiple times, or trying to overdose on multiple SSRIs might result in serotonin syndrome, which is extremely unpleasant, but not fatal.

Medications are generally formulated to be safe. That's a good thing, it keeps them from killing people over time, and most people aren't trying to die. But it means that ODs are generally not a good way to commit suicide.
 
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h4ppyhypoxia

h4ppyhypoxia

Experienced
Aug 8, 2026
232
any medication CAN be fatal in large doses, people have died from overdosing, but they are the minority, you have to remember they are prescribing this medication to depressed people, so it has to be safe for them, if you could easily od on antidepressants, then they wouldnt be prescribed to one of the most at risk for suicide groups in the population

overdosing in general does not reliably lead to death, but if you overdose on SSRIs, its a good way to permanently damage your brain chemistry and leave yourself way worse off for the rest of your life, i get the desperation, but this is a non method, the SRC has information about why overdoses DO NOT work in the majority of cases (no matter what you od on)
 
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CopingWithSenility

CopingWithSenility

Member
Sep 8, 2026
14
I highly advise not trying it. It will not go well
mod note: this has been added to the suicide resource compilation at the top.

This has been made in response to the ever increasing amount of posts made about highly unlikely methods. Please read before posting about one of these methods or feel free to link if someone does post about them.

This thread is meant to prevent people from trying methods that are almost certain to not kill them but likely to cause harm, whether temporary or permanent. Any method listed in this thread should not be attempted by anyone, and should not be considered a method. I do not give advice on methods that will kill you, as it goes against my personal beliefs, so I will not be responding to any questions asking about them. This has been made for harm reduction to prevent people from ending up in a worse off situation.

Prescription medications
This method has a lot more nuance to it, as certain prescriptions have a high likelihood of lethality when taken in the right doses, while others have next to 0 chance. Generally, most prescriptions have a low chance of killing you. Psychiatric medications are the most discussed on this forum, and are also on the lower end of having any shot at killing you. Antidepressants vary in chance of killing you, though even the most toxic (tricyclics) have only about a 14% chance, not a very good statistic. At worst, certain antidepressants have only a 0.5% chance. Other medications, such as those taken for chronic conditions, vary wildly, however the list of those with a high chance of killing you is significantly shorter than the ones with little or moderate chance. Obviously it would be far too tedious to go and list off all of them.
 
K

keat6890

Member
Mar 6, 2025
14
Please don't attempt this method. It's explicitly deemed as a non-method that shouldn't be attempted, as it has a pitful success rate docummented, about only 0.5% to 14% depending on the type of an antidepressant if I recall correctly. I think it's even mentioned in one of the pinned megathreads on this forum. I'm really sorry you're feeling this way, and I really hope that you can find a solution that ultimately brings you release. But please, reconsider this method, as it has a really high chance of giving you a painful outcome that you probably, certainly don't need and don't wish upon yourself.
Thank you so much
 
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DeathSweetDeath

DeathSweetDeath

Visionary
Nov 12, 2025
2,422
Here's all the valuable info this site has to offer that you somehow missed…



 
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carfemtanyl

carfemtanyl

Experienced
Nov 18, 2025
222
very unlikely unless it's an insane amount of amitriptyline
 
Cunanan77

Cunanan77

One of life's tragedies
Aug 2, 2022
30
You'll just get serotonin syndrome which is fatal sometimes but not very pleasant
 
intr0verse

intr0verse

Mage
Jan 29, 2021
516
Here's all the valuable info this site has to offer that you somehow missed…



If i will ever open a thread talking about OD's, i will curse anyone linking to the first two threads, with living a long happy life. :smiling:
 
h4ppyhypoxia

h4ppyhypoxia

Experienced
Aug 8, 2026
232
If i will ever open a thread talking about OD's, i will curse anyone linking to the first two threads, with living a long happy life. :smiling:
may i ask why? (genuine curiosity) oding is pretty unreliable and from the stats ive read, most people survive ods, you cant really calculate what a "lethal dose" will be for you, and youre at risk of vomiting up all the pills bc youd have to take a very large amount of them
 
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intr0verse

intr0verse

Mage
Jan 29, 2021
516
may i ask why? (genuine curiosity) oding is pretty unreliable and from the stats ive read, most people survive ods, you cant really calculate what a "lethal dose" will be for you, and youre at risk of vomiting up all the pills bc youd have to take a very large amount of them
Because not every od is the same. Technically, drinking N or SN is an overdose, yet if you know the right drugs and plan well, they work. So, instead of just linking to threads that treat od's the same, i would be more content with being told why a certain medicine isn't likely to work.
The OP of the second thread linked above, died using what i would consider a non-method, or at least he planned to use one anyway...
 
h4ppyhypoxia

h4ppyhypoxia

Experienced
Aug 8, 2026
232
Because not every od is the same. Technically, drinking N or SN is an overdose, yet if you know the right drugs and plan well, they work. So, instead of just linking to threads that treat od's the same, i would be more content with being told why a certain medicine isn't likely to work.
The OP of the second thread linked above, died using what i would consider a non-method, or at least he planned to use one anyway...
yeah i get that, its just hard to calculate the lethal dose which is what puts me off oding (high failure rates + high complication chance scares me off), people die from ods every day, its just not something id personally want to risk, i remember the pph saying that ods should only be considered as a last resort if all other methods are not available (specifically talking about opiates)
 
intr0verse

intr0verse

Mage
Jan 29, 2021
516
yeah i get that, its just hard to calculate the lethal dose which is what puts me off oding (high failure rates + high complication chance scares me off), people die from ods every day, its just not something id personally want to risk, i remember the pph saying that ods should only be considered as a last resort if all other methods are not available (specifically talking about opiates)
Well, more than half of the methods listed in the PPeH are technically overdoses...
Opioids are indeed unpredictable, they are lethal in overdose but not always reliable. What i was trying to point out is that it's far more constructive to talk about a specific drug's reliability than to just throw some links with generalities, saying all od's are not reliable.
 
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DeathSweetDeath

DeathSweetDeath

Visionary
Nov 12, 2025
2,422
Because not every od is the same. Technically, drinking N or SN is an overdose, yet if you know the right drugs and plan well, they work. So, instead of just linking to threads that treat od's the same, i would be more content with being told why a certain medicine isn't likely to work.
The OP of the second thread linked above, died using what i would consider a non-method, or at least he planned to use one anyway...
SN is not an overdose. It's not a medicine or drug, it's a poison. I'd gladly accept that curse just as long as I could use a time machine to go back & undo some stuff first 🙃.
 
intr0verse

intr0verse

Mage
Jan 29, 2021
516
SN is not an overdose. It's not a medicine or drug, it's a poison. I'd gladly accept that curse just as long as I could use a time machine to go back & undo some stuff first 🙃.
Given that it has a safe dose and it's being used in the food industry, anything abive that safe dose, it's an overdose.
 
A

abcdefg789

Experienced
May 8, 2026
234

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