Despite it just only occuring in rare cases, it's still a nice heads up to know. Doctors don't seem to bring up the rare serious side effects as often as they should.
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CiproKilledMe
Experienced
- Mar 23, 2021
- 243
Some of us are on this website solely because we've been severely harmed by Big Pharma, so we're once bitten, twice shy when it comes to Rx drugs. And no, not all drug side effects are equal. Black box warning drugs are no joke and the heightened warnings exist for good reason. Note that meto has one of the absolute lowest ratings on askapatient (an abysmal 1.4/5): https://www.askapatient.com/viewrating.asp?drug=17854&name=REGLAN
jodes2
Hello people β€οΈ
- Aug 28, 2022
- 7,736
I have mild akathesia already so metro is to be avoided for me. Instead I'll take domperidome. Knowing my luck I'll survive SN and have to face shit afterwards
I do wish you luck in finding peace- good luck, not the bad kind. :)
Still using it. Using Meto with Zofran. Whatever happens, happens. I'll be dead. I'm not gonna survive.
If you're followinh STan's guide pretty closely, with pain relievers and hoepfully propranolo, the odds are on your side to be able the achieve peace. Best of luck.
At least pain relievers- Tylenol or Advil- will help with the risk of headaches- this can make the difference between callingt for help or not. Propranolol can help for dealing with the rapid heart rate, which is another thing that has lead some people to call for help- a prescriptino is needed for this, but online doctors can prescribe this.
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jodes2
Hello people β€οΈ
- Aug 28, 2022
- 7,736
Lastsauce
Experienced
- Dec 22, 2019
- 258
Same here, no noticeable effect at all. I also tried meto during a mild stomach bug and it did nothing.
20g+ SN in 50ml of water seems to be such a strong irritant that does meto even have a chance of helping?
Hello SS,
I hesitated to start this tread because i guess some people will bash it because it's suggested in the PPeh. But after again seeing someone going very bad on Meto yesterday here on SS i decided to start a tread about the dangers and sometimes life long consequences of Metocloperamide.
Meto is a very dangerous anti emetic drug that can cripple people for life after short term use or single dose. use. A lot of people don't know this, and talking here about 'take some Meto' to test, but they're totally unaware of the dangers they expose themselves to with an unnecessary test. They think it's the same like taking a innocent tylenol for a headache, it's not! They don't know what they're talking about and what they ingest. (I can't blame them even doctors don't tell you this)
Meto is well known for it's dystonic reactions that cripple people for life and Akathesia. There are a lot of lawsuits against the Pharmaceutical companies that produce this drug.
In my opinion Meto is more dangerous than N itself.
From N people die, but from meto people get tortured for months/years on end with Dystonia and/or Akathesia and after that they take their life because they can't handle the extreme suffering of the long lasting or permanent side effects.
"Metoclopramide has an average rating of 4.0 out of 10 from a total of 468 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 62% reported a negative effect."
source (the reviews speak for itself):
Metoclopramide Reviews & Ratings - Drugs.com
Reviews and ratings for Metoclopramide. 521 reviews submitted with a 3.9 average score.www.drugs.com
View attachment 90597
Source: https://www.drugwatch.com/reglan/lawsuits/
This unfortunate person has a dystonic reaction after taking Metocloperamide and is battling the side effects for years! (i'm sorry for him). Just read the comment section and see there are enough people hurt by this drug.
Maybe i will get bashed that i scare monger, that i'm only pushing horror stories, that it's 0,00001% But it's not true it's pretty common. Just do your own research.
I'm interested in side effects of meds, because i'm completely crippled by an 'innocent' pharmaceutical med myself. That's why i'm here in the first place. And i wish someone informed me before so that it could be prevented (doctors will not). Unfortunately for me it's too late.
If i can provide only 1 person from this pharma-sufferhell then i've reached my goal.
Do with the info what you want, i'm not here to scare monger you. And i'm sorry if it scares you. I'm only here to inform you and to tell you it's better not to do unnecessary tests with it on forehand.
Of course not everybody will get such adverse reaction, everyone is different, but people need to be informed at least of certain possibilities.
Some people can take the Meto and decide to giving up on CTB, but may have their life ruined because of Meto, so weigh up the decision yourself.
I'm curious to the discussion,
Take care!
As someone who sometimes jumps on the fear-mongers hear, I'll say that this is fair enough warning. I was prescribed Reglan years ago for digestie issues that we thought might have been gastroparesis, at the time. (My mother has it.) I was given the same warnings, and the medication was listed as extreme. When I picked it up from the pharmacist, I had to sign that I understood the risks, etc, and was warned to stop immediately if I started having any uncontrolled movements. Sure enough, in the first few days, I did, especially in my legs, and my doctor told me to stop. The tics stopped, too, and I had no long-term effects.
(After more testing, it turns out that it wasn't gastroparesis, anyway, but IBS with slow digestion.Funny thing is that I told my mother about this, and she got defensive and accusatory, saying that what I was experiencing with the Reglan wasn't real, that the TD wouldn't start that soon. She herself experiences it, and yet she swore by Reglan. For some reason, she was set on my having gastroparesis, too.)
Anyway, while I don't remember experiencing anything more than TD, it did kick in rather fast.
That said, I will still probably take it with N, if only because it will be a one-time thing, and I won't be worried about TD after the fact...but I've already tried it once, and know what to expect, so I'm willing to take that risk.
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I'm not really sure but I'm pretty sure the Meto has a gastric emptying effect, which would mean more of the nitrite goes into your intestines quicker.
I think that's another big reason why this medication is suggested.
RN12
Student
- Jul 25, 2021
- 180
Yes you're right on that. Some people get TD for years after one pill (also possible from antipsychotic SSRI etc)
Luckily you came away with at fast :)
There are five other antiemitics listed in Stanhs Guide plus some over the counter options, but they may not be as effective. The odds of a bad reaction to meto are pretty low, but for the peopel who do get a bad reaction it can be terrible- so it's up to each person to try to estimate risks the best they can, since most methods that most people can access have some risk of turning out badly- with careful planning you can make the chances of success as high as possible.
Okay so I need to give personal opinion on this. I've been a critical care nurse for over 30 years. I've given Reglan countless times. Not once have I had a patient develop tardive dyskinesia or any extrapyrimadol symptoms. And this is with single dose and multiple dose administrations. So bottom line for me is that I probably wouldn't worry about it. Not saying it can't happen but that it probably won't.
This is excellent to know, to have your expertise, this helps a lot, :)
define countless? the fear-mongering of meto on this thread is freaking me out. Im not sure why people are so damn worried about the meto when within an hour or so of ingesting it the SN will be knocking you unconscious and then killing you.
Exactly.
Also taking Benadryl before the meto is supposed to help with these symptoms.
oh great, another drug to add to the list haha. Is that because of that person that was given it in the hospital and got better? argh all this anecdotal stuff is driving me insane. Imma have to just stop reading at this point or ill never do it. The cons of meto definitely seem to outweigh the pros..aka the SN being successful and the attempt being successful.
There is mixed infomration on this. The most common brand name for meto is Reglan, and if you search on youtube by "Reglan side effects" many people have posted videos of really bad experiences with this, being disabled years later sometimes from one dose- it's not fear mongering, it's providing information on both sides so that people can make an educated decision. Obviously if ctb works it doesn't matter, but if an attempt fails then a person may be prevented from making another attempt if they have bad side effects from meto. I have both meto and Meclizine, and at this point I will probably use over the counter Meclizine due to this concern, even though meto is a much stronger antiemitic.
I wouldn't freak out if I was you. By saying countless times I mean that I would administer it probably 2-3 shifts a week out of 4 shifts. I've worked in Level 1 trauma centers and/or teaching hospitals so there is a large patient population that would get this med. Whether it was my patients getting it or another nurse's on the same unit, I have never encountered a problem with side effects. And I literally mean never. I've been a nurse for 25+ years and it is an incredibly rare side effect.
I believe you , but there is still other information out there like the following:
So how much is a large dose? I've read somewhere that 30mg caused symptoms from one dose, though I can't find the source right now, and this is the dose recommended by Stan's guide. Would it better better to just use 10mg?
Do you know what dosages were used without having issues? Were people regularly getting 30mg without getting tardive dyskinesia? This is the dosage in Stan's guide. Thanks for any thoughts on the dosage.
In your last post you said 30 years, now you're saying 25+ years..which is it? Sorry I'm not meaning to not be trusting but this is very serious. I really hope you are telling the truth. That being said, if it was so dangerous that you could develop dyskinesia after like 1 dose I just can't believe it would have past clinical trials and still be available all of these years. I feel like it's just fear mongering. Yes TD seems very frightening but I just can't imagine the likelihood of it being even LOW after ONE dose being on the market all these years. SURELY the FDA would pull it from the market right??! RIGHT!?!? Fuck.
In PPH, on the AE section he does say for meto 20-30mg. You could just do 20mg and combine with another AE. Thats what im going to do, combine 20mg meto with zofran. He specifically mentions meto for a reason I feel like for the gastric emptying..and he says that TD like symptoms are very rare. I think I feel like you're worried about something that has a likelihood of like .01%. You're only taking it ONE time, not for weeks or months. And you're also literally dying within hours of taking it that one time..
why are you worried about getting TD when you are dying within hours of taking it?? The video says its more likely over long periods of time and with the elderly. Take like 20mg and have a backup glass of SN and you'll be okay. If it was even remotely common to develop it would NOT be on the market today in 2022. I just can't believe that. PPH says it is very rare.
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The reason I am worried about this is because a number of people who have posted here did ctb on their second sn attempt- it usually works on the first attempt, but not always. If you get a avery bad reaction you may not be able to do a second attempt. I think I read of a case of a person getting TD from one dose. I do know of a case here where someone (@Cheers) used Meclizine (over the counter) instead of meto and it seemed to work. So it is very important to people who are trying to get to peace to determine what the best meds are to use for this method. It is not fear monbgering to say that there is some important meto- it is just gathering all available information to try to determine the best approach. There are other grey areas with sn- whether to take an antacid or not is debated a lot. Debating a topic is not fear mongering, it is gathering information so that people can make the best informed decisions for themselves. Using terms like fear mongering to try to suppress debate or discussion of a topic is definitely counter productive.
Sorry, fear mongering isn't the right term you're right. I think overly anxious and overly precautious is better. Don't get me wrong I'm right there with you with the paranoia and fear, but the overwhelming data is showing that meto is safe for most people, especially only taking it one time. I think using an AE that is too weak and not having enough SN absorb is far worse of an outcome than worrying about the small chance you react negatively to the meto. Even if you react negatively to the meto, it will likely just be some unpleasant symptoms leading up to the SN, the AE affect of the meto would still very likely work, it would just be less peaceful of a process than hoped. But again I feel like a very large majority of the population are going to be completely fine taking it that one time, I just don't think the PPH would strongly recommend meto if that wasn't the case, he explicitly says that side effects are very rare. And even if you do have side effects from it, its not going to be full blown TD after one use that manifests within one hour. Think about ALL of the people that have taken meto over the years, many of them taking it multiple times. I totally understand your fears though, TD is absolutely horrifying and my heart goes out to anyone that has it as a result of meto. I wish there was a safer dopamine antagonistic AE that didn't cause this. But do whatever it is you feel is best. I would just hate for you to use an AE that is too weak, vomit all of the SN and fail when PPH clearly states that OTC AE are not going to be strong enough.
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Based on the comments in response to the following TD video many people have had terrible responses based on one dose- the video shows how bad this can be. Currently I am leaning towards Meclizine because it did work for @Cheers. Others have taken it for years without issues- maybe it if based on a person's genetics.
Yeah the side effects are definitely scary. But PPH strongly recommends a dopamine antagonist due to its ability for the SN to absorb quickly. I guess it's all a gamble. I wish there was a way to know if you will react badly to the meto before taking it. It seems that it's an allergic reaction that most people suffer from and that Benadryl makes it better, idk. Sounds like you have your mind made up not to take it so trust your gut and don't do it.
Honestly I'm still trying to assess the risk-reward and since I have both I will up until the time it will be used, within the nxt week or wto- youtibe has some interesting examples with incomplete information. @Cheers did seem to ctb using Meclizine last October, and some have seemed to without any antiemitic, though meto seems to really help if you don't get the bad side effects.
Yeah, the more I look into meto the more using it scares me, especially at such a high dose of 30mg. I apologize for diminishing any of your fears, it's definitely something to be concerned about. It sucks how trial and error drugs are. We could both be totally fine with meto and not know it and be freaking out for nothing, or it could be totally awful and we will hate ourselves for trying it. It's really frustrating,
CiproKilledMe
Experienced
- Mar 23, 2021
- 243
For me it's not so much the TD I'm concerned with, it's all the reports of meto causing people to have massive anxiety and panic attacks. I'm already going to be extremely anxious and scared when the time comes to drink my lethal poison--I certainly don't need or want any help being more scared. Ideally I don't want my last moments on earth being spent in the throws of a massive drug-induced panic attack. Not to mention, if the panic/anxiety is great enough it could cause me to have to abort the entire thing.
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