Like i said above i find ondansetron mild and no problem. I just read one suggestion that it will be adequate for our purpose taken in a single dose of 24mg (3x what inormally take) 40 minutes before.
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Like i said above i find ondansetron mild and no problem. I just read one suggestion that it will be adequate for our purpose taken in a single dose of 24mg (3x what inormally take) 40 minutes before.
CiproKilledMe
Experienced
- Mar 23, 2021
- 243
Nooooooo. Domperidone has a black box warning for potentially fatal cardiac issues and is banned in the US!
How to Request Domperidone for Expanded Access Use
FDA recognizes that there are some patients with severe gastrointestinal motility disorders that are difficult to manage with available therapy for whom domperidone’s potential benefits may justify its potential risks. Patients 12 years of age and older with certain gastrointestinal (GI) conditions
I cannot fathom why anyone would ingest a black box drug and risk permanent or life-threatening side effects in order to avoid some freakin' nausea, but welcome to the mad world we're living in! I personally would rather just feel nauseous.
Shu
As above, So Below.
- Jan 21, 2022
- 2,487
You guys are scaring me man. 
I'm still taking the stat dose of meto.
Worst that happens is I become paralyzed within those 45 minutes and I'm not able to drink the sn.
I'm still taking the stat dose of meto.
Worst that happens is I become paralyzed within those 45 minutes and I'm not able to drink the sn.
Have there been discussions about substituting 550mg ginger capsules for Meto, as it's basically an antiemetic anyway? Obviously it's not going to stop the vomiting, but it may help with the nausea just a little and should have a stomach emptying effect
Sorry if this has been asked before but I just joined and for the life of me cannot find the search feature on this website
Sorry if this has been asked before but I just joined and for the life of me cannot find the search feature on this website
Foresight
Enlightened
- Jun 14, 2019
- 1,397
Are these drugs known to cause these issues within the hour? I'm truly confused by the alarm. You're taking these drugs as part of a suicide kit. It doesn't matter if it causes heart attacks or brain damage, you're turning your blood into chocolate pudding or shutting down your respiratory system.
Don't run tests on them. Wait until it's time to damage all biological function anyway. I'm more worried about spending my last minutes retching than "longterm damage" when I'm dead.
Don't run tests on them. Wait until it's time to damage all biological function anyway. I'm more worried about spending my last minutes retching than "longterm damage" when I'm dead.
Hello SS,
I hesitated to start this tread because i guess some people will bash it because it's suggested in the PPeh. But after again seeing someone going very bad on Meto yesterday here on SS i decided to start a tread about the dangers and sometimes life long consequences of Metocloperamide.
Meto is a very dangerous anti emetic drug that can cripple people for life after short term use or single dose. use. A lot of people don't know this, and talking here about 'take some Meto' to test, but they're totally unaware of the dangers they expose themselves to with an unnecessary test. They think it's the same like taking a innocent tylenol for a headache, it's not! They don't know what they're talking about and what they ingest. (I can't blame them even doctors don't tell you this)
Meto is well known for it's dystonic reactions that cripple people for life and Akathesia. There are a lot of lawsuits against the Pharmaceutical companies that produce this drug.
In my opinion Meto is more dangerous than N itself.
From N people die, but from meto people get tortured for months/years on end with Dystonia and/or Akathesia and after that they take their life because they can't handle the extreme suffering of the long lasting or permanent side effects.
"Metoclopramide has an average rating of 4.0 out of 10 from a total of 468 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 62% reported a negative effect."
source (the reviews speak for itself):
Metoclopramide Reviews & Ratings - Drugs.com
Reviews and ratings for Metoclopramide. 505 reviews submitted with a 3.9 average score.www.drugs.com
View attachment 90597
Source: https://www.drugwatch.com/reglan/lawsuits/
This unfortunate person has a dystonic reaction after taking Metocloperamide and is battling the side effects for years! (i'm sorry for him). Just read the comment section and see there are enough people hurt by this drug.
Maybe i will get bashed that i scare monger, that i'm only pushing horror stories, that it's 0,00001% But it's not true it's pretty common. Just do your own research.
I'm interested in side effects of meds, because i'm completely crippled by an 'innocent' pharmaceutical med myself. That's why i'm here in the first place. And i wish someone informed me before so that it could be prevented (doctors will not). Unfortunately for me it's too late.
If i can provide only 1 person from this pharma-sufferhell then i've reached my goal.
Do with the info what you want, i'm not here to scare monger you. And i'm sorry if it scares you. I'm only here to inform you and to tell you it's better not to do unnecessary tests with it on forehand.
Of course not everybody will get such adverse reaction, everyone is different, but people need to be informed at least of certain possibilities.
Some people can take the Meto and decide to giving up on CTB, but may have their life ruined because of Meto, so weigh up the decision yourself.
I'm curious to the discussion,
Take care!
Yeah--about 20 years ago,doctor prescribed Reglan for my acid reflux--Good Lord,it made me hyper as hell, Iwas totally wired and got insomnia--stopped taking it after a few days, stuff is a nightmare tosome people
Shu
As above, So Below.
- Jan 21, 2022
- 2,487
RN12
Student
- Jul 25, 2021
- 180
'I went to the ER for extreme nausea and vomiting. They gave me Reglan. Within minutes, I started having a psychiatric break'
Source: https://www.drugs.com/comments/metoclopramide/
Will this happen to everyone, no certainly not! I only can say, it 'is' possible and it happens.
Again i will say, i'm sorry for the confusion, or that people get scared. But i rather see people scared than with an adverse reaction like member Puddle a couple days ago. (for him it was after 2h 30m i see in his tread). I've seen this more, I just had to warn.
https://sanctioned-suicide.net/threads/bad-reaction-with-meto-right-now.88704/#post-1578132
interesting connection.
stimulants such as amphetamines, methylphenidate, and methamphetamine, can lead to twitching and spasming (similar involuntary motor activity as seen in antipsychotic extrapyramidal side effects), constant state of motion, hyperactivity / mania, absentmindedness due to racing thoughts and lack of singular focus.
of note, stimulants are dopamine agonists or reuptake inhibitors - ie they keep an excess amount of dopamine in the synapse and neurons are unable to 'tidy up' as they normally would. with prolonged use the brain downregulates the receptors and / or stops producing as much dopamine on its own. considered to be a chemical imbalance in the opposite direction as schizophrenia and whatever the fuck else they use to justify forcibly drugging people with antipsychotics is parkinson's - which is treated with levodopa. yall can put 2 and 2 together on that one. ADHD somehow also requires long term pharmacological treatment with stimulants.
whereas metoclopramide is both a dopamine and serotonin antagonist, ondansetron is only a serotonin receptor antagonist - which has its own problems, but not the set of symptoms described as a result of dopaminergic meddling. one need look no further than SSRI permanent side effects, long term withdrawal and its iatrogenesis to see that big pharma is far from innocent.
they are playing with fire pretending to be god. the chemical imbalance theory of mental illness is backward - their drugs cause changes to the brain that result in psychiatric issues. they invented that theory to profit. and then the fallout creates lifelong customers for them. brilliant marketing scheme, i must admit.
Cathy Ames
Cautionary Tale
- Mar 11, 2022
- 2,104
I mean, that's the question. When used for its intended purpose, they have you take it 30 minutes before eating, so it likely starts doing something right around then.
Yup. I think the concern is the question of how likely it is that it will do something bad enough to prevent the person from proceeding to prepare and drink the SN. In that case it might matter if the effect ends up being permanent.
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houseofleaves
and this with thee remains.
- Jan 14, 2022
- 545
rationaltake
I'm rocking it - in another universe
- Sep 28, 2021
- 2,712
I get what you're saying.
The worry particularly with SN is that you will throw it up. There will not be enough SN in your system and the attempt will be unsuccessful.
There are reports of this happening on here.
Suicidebydeath
No chances to be happy - dead inside
- Nov 25, 2021
- 3,561
I'm just about to order metos. From the same place I could get Prochlorperazine.Has there been any consensus yet on what the best anti-emetic is?
HopefulButPrepared
Experienced
- Jun 22, 2022
- 247
RN12
Student
- Jul 25, 2021
- 180
I wasn't aware you could take 24mg at once. I wonder what the possible negatives of this could be
Edit: sorry just went and researched it and apparently they're saying 24 mg a day but not to exceed that. I'm really considering taking zofran because I have some of it.
Euthanza
Self Righteous Suicide
- Jun 9, 2022
- 1,431
This is another reason why people needs to legalize voluntary euthanasia and assisted suicide. To make sure Meto or any kind of medicines won't fail a pleasant death.
My understanding is that benadryl will stop a TD reaction from meto. I can't remember the recommended dose to stop the reaction or how someone came up with it, but I want to say 50 mg? But my memory sucks so please do NOT assume that's correct. Does anyone else know?
wait.what
no really, what?
- Aug 14, 2020
- 981
Zofran/Ondansetron is fine as an antiemetic. However, my understanding is that meto was partly chosen for the recommended SN cocktail because it speeds up gastric emptying. This will get the SN out of your stomach and into your small bowel as quickly as possible. Once SN has moved past your stomach, you can't throw it up. Medical personnel also can't remove it with gastric lavage.
The problem with Zofran is that it can slow down gastric emptying. I can't really tell you exactly what percentage of people get this effect, or how often it might happen with a first dose. However, if Zofran is not part of the recommendations in Stan's Guide, I suspect the reason at least partly involves gastric emptying speed.
I have to concur with those who have pointed out that since the goal here is to die within hours, the risk of "long term" negative side effects isn't especially relevant. I do understand the fear of being out of control over your own body, which is actually why firearms have long been my go-to suicide method. "Peaceful" can mean different things to different people, but to me it means very quick, very effective, and reasonably accessible. I guess I'd caution people against assuming that a method is peaceful just because it involves ingesting poison instead of using a gun or a blade. Poison can do some horrendous things to people.
The problem with Zofran is that it can slow down gastric emptying. I can't really tell you exactly what percentage of people get this effect, or how often it might happen with a first dose. However, if Zofran is not part of the recommendations in Stan's Guide, I suspect the reason at least partly involves gastric emptying speed.
I have to concur with those who have pointed out that since the goal here is to die within hours, the risk of "long term" negative side effects isn't especially relevant. I do understand the fear of being out of control over your own body, which is actually why firearms have long been my go-to suicide method. "Peaceful" can mean different things to different people, but to me it means very quick, very effective, and reasonably accessible. I guess I'd caution people against assuming that a method is peaceful just because it involves ingesting poison instead of using a gun or a blade. Poison can do some horrendous things to people.
Mofreeko
Arcanist
- Apr 7, 2019
- 479
I have first hand experience with benadryl stopping reactions from meto. About two years ago I took meto in preparation for drinking N and had a severe reaction. I thought I was having an allergic reaction and I was panicking so I called an ambulance. The doctors at the hospital also thought I was having an allergic reaction so they gave me an IV of benadryl. I immediately felt normal again. The meto symptoms kept coming back though and they had to give me benadryl two more times after around 2 or 3 hours or so. After around 8 or so hours the meto reaction stopped and I was able to go home. I was pretty lucky that although I was misdiagnosed as having an allergic reaction they still gave me the right treatment and it also gave me a cover story to my family who came to come get me. I'm still confused why the doctors stuck with the allergy diagnosis though because I told them what I took and surely they could have looked up the symptoms. But whatever.
I took meto with another drug to prevent drug-induced nausea and vomiting and it did nothing for the nausea nor the vomiting. I don't remember if it did *something* negative, but it did nothing for the nausea.
On two separate occasions, I took a small amount of SN. The first time, I was noticeably nauseous but didn't vomit. The second time I took it, I took an acid reducer (famotidine, H2 antagonist) and felt no nausea. I realize that this is a post about the negative effects of meto, but IMO it is not something I would ever take again. An acid reducer is much safer, not to mention that it did the job that meto did not.
If I was to bet on one or the other "in the moment" and to avoid vomiting, I would 100% take an acid reducer. I understand that meto works to block the urge to vomit, but the urge to vomit is normally also created by a physiological response in your body, and IMO, it is better to block that physiological reaction that causes the urge to vomit that to block the urge itself. Not a doctor. This is just my personal experience.
On two separate occasions, I took a small amount of SN. The first time, I was noticeably nauseous but didn't vomit. The second time I took it, I took an acid reducer (famotidine, H2 antagonist) and felt no nausea. I realize that this is a post about the negative effects of meto, but IMO it is not something I would ever take again. An acid reducer is much safer, not to mention that it did the job that meto did not.
If I was to bet on one or the other "in the moment" and to avoid vomiting, I would 100% take an acid reducer. I understand that meto works to block the urge to vomit, but the urge to vomit is normally also created by a physiological response in your body, and IMO, it is better to block that physiological reaction that causes the urge to vomit that to block the urge itself. Not a doctor. This is just my personal experience.
I have seen from as few online sources that this can happen from one dose- now I am leaning towards Meclizine, an over the counter antiemitic.
Hello SS,
I hesitated to start this tread because i guess some people will bash it because it's suggested in the PPeh. But after again seeing someone going very bad on Meto yesterday here on SS i decided to start a tread about the dangers and sometimes life long consequences of Metocloperamide.
Meto is a very dangerous anti emetic drug that can cripple people for life after short term use or single dose. use. A lot of people don't know this, and talking here about 'take some Meto' to test, but they're totally unaware of the dangers they expose themselves to with an unnecessary test. They think it's the same like taking a innocent tylenol for a headache, it's not! They don't know what they're talking about and what they ingest. (I can't blame them even doctors don't tell you this)
Meto is well known for it's dystonic reactions that cripple people for life and Akathesia. There are a lot of lawsuits against the Pharmaceutical companies that produce this drug.
In my opinion Meto is more dangerous than N itself.
From N people die, but from meto people get tortured for months/years on end with Dystonia and/or Akathesia and after that they take their life because they can't handle the extreme suffering of the long lasting or permanent side effects.
"Metoclopramide has an average rating of 4.0 out of 10 from a total of 468 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 62% reported a negative effect."
source (the reviews speak for itself):
Metoclopramide Reviews & Ratings - Drugs.com
Reviews and ratings for Metoclopramide. 505 reviews submitted with a 3.9 average score.
View attachment 90597
Source: https://www.drugwatch.com/reglan/lawsuits/
This unfortunate person has a dystonic reaction after taking Metocloperamide and is battling the side effects for years! (i'm sorry for him). Just read the comment section and see there are enough people hurt by this drug.
Maybe i will get bashed that i scare monger, that i'm only pushing horror stories, that it's 0,00001% But it's not true it's pretty common. Just do your own research.
I'm interested in side effects of meds, because i'm completely crippled by an 'innocent' pharmaceutical med myself. That's why i'm here in the first place. And i wish someone informed me before so that it could be prevented (doctors will not). Unfortunately for me it's too late.
If i can provide only 1 person from this pharma-sufferhell then i've reached my goal.
Do with the info what you want, i'm not here to scare monger you. And i'm sorry if it scares you. I'm only here to inform you and to tell you it's better not to do unnecessary tests with it on forehand.
Of course not everybody will get such adverse reaction, everyone is different, but people need to be informed at least of certain possibilities.
Some people can take the Meto and decide to giving up on CTB, but may have their life ruined because of Meto, so weigh up the decision yourself.
I'm curious to the discussion,
Take care!
This thread is so important that it should be included with Stan's Guide so that people know the risks of this.
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I took it for a few days, back in the year 2000 for acid reflux, made me hyper, got 3 hours sleep in 72 hours--first and last time taking it
Sounds very rough, and you got very lucky compared to the guy in the video- very informative and helpful take on this.
Lawliet
b a n g
- Sep 15, 2020
- 346
i take metaclopramide for gastroparesis twice a day for the past year, i have had zero side effects.
what you have to keep in mind is that every drug has some terrifying side effect that happened to a very small amount of people. this drug has helped me a ton. i don't thing you're fear mongering but you are blowing this out of proportion.
it's important to know side effects but focusing on this incredibly rare one isn't helping anyone.
what you have to keep in mind is that every drug has some terrifying side effect that happened to a very small amount of people. this drug has helped me a ton. i don't thing you're fear mongering but you are blowing this out of proportion.
seriously, look into any drug and you will find lawsuits and the most terrifying thing that ever happened. everyone's different, and the real problem is taking this without a prescription because doctors can see what other medications you're on and what health problems you have. look into the section on webmd or wherever to see who shouldn't take this drug rather than "oh look at this terrifying video that happened to this very tiny tiny section of people who took it." do these accounts also list the other meds their on, etc.
it's important to know side effects but focusing on this incredibly rare one isn't helping anyone.
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Mofreeko
Arcanist
- Apr 7, 2019
- 479
Lawliet
b a n g
- Sep 15, 2020
- 346
Mofreeko
Arcanist
- Apr 7, 2019
- 479
It's good to have your perspective. The cases that are bad ae really bad, as you can see in the video on the first post. WHat are the odds of bad side effects, and are certain people more vulnerable than other.s Obviously you must have seen the black box warning on meto about tardive dyskinesia, and prescriptions for meto are doqwn a lot in recent years as more and more doctors stay away from it. Some further research show sthat it can happenb in up to 2% of patiients after taking it for three months, so it's lower risk than some articles make you think. It's definitely helpful to try to assess whether it should be ysed for ctb or not- obviously it ctb works than no worries, but what if it doesn't work?
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