Has anyone used DD for SN? It seems to be good purity but I can't find much about the site.
What's DD?
I'm a bit confused about the meto - these are prescribed or readily available drugs so how could one dose be dangerous ? I'm also confused with doses - does stat dose just mean recommended dosage on the box ? The guide only gives the stat dosage for Metoclopramide - would it be the same for the others or would it vary depending on the stat dosage recommended for each one ? i.e. 30mg is the stat dose for Metoclopramide but the stat dose could be different for the others ?
Also, you have to remind yourself that some drugs have different ways of working in the body and what they are aimed at doing.
For example, you could take 600mg of ibuprofen for a headache and it'll work, hopefully within a 1 to a few hours. If you were started on an antidepressant, it's effect may not be felt until 3 to 5 weeks later depending on the individual as everybody's body works differently. Must drugs are metabolized by the liver which have various enzymes, such as CYP 3A4, 2D6, etc. So, people who are "poor metabolizers" may not get the effect of the drug itself as these enzymes are not capable enough to convert the drug into an active metabolite (active compound which works in the body). Furthermore, a drugs effect also depends on the half life.
Sorry if this sounds too complicated. I just want you to understand that certain medications can work within minutes to hours and others from days to weeks. This all depends on the person's enzymes found in the liver and how they function varies from person to person.
I've never taken metoclopramide for nausea so I couldn't tell you if a stat dose will do anything. I'm my opinion, to get the best effect from metoclopramide is to take it over days so that it reaches therapeutic levels. I could be wrong about this as if never needed the medication before. I guess you have to decide if you want to just take stat dose vs several doses over several days or whatever. Stat doses of ibuprofen or paracetamol works well in general. But, stat doses of, say, amitriptyline for pain/depression do not.