Resource SN FAQ - Antiemetics, Benzo, Antacid, Beta-blockers, Painkillers [DRAFT]

[Quarky00]

Hi,
Rough draft – please suggest information, links, changes. Aimed at 95% of target audience (FAQ shouldnt address exceptional cases/patients). Written for myself over 3 months , pasted with little proof-reading. Any harmful, inciting, or misleading info here should be removed. So let me know.
Q

– – – – – – – – – – – – – – – – – – – – – – – – – – – – – –

Disclaimer & Information​

Is this a guide?	NO. Goal – clarify frequent questions , provide links to read Most had been addressed in the guide or thread. First read Stan's Guide and Stan's thread Almost nothing here is new
How to find MEDICATION X ?​ Can I use MEDICAION Y ?	Can't answer that.​ There are literally 100s of brands(!) of AE, antacids, benzo, painkillers.​ You must search brand and compare ingredients.​
Should I trust this FAQ?	NO. Many things are common knowledge/practices. This is not scientific, do research.

SUMMARY​

	Function​	Hard to get​	How often used with SN (very rough estimate)​
Better SN intake​
Antiemetics (AE)	Stomach emptying, anti-vomiting	Yes	70%
Antacid / Acid-Reducers	May improve absorption	No	80%
Ease symptoms​
Painkillers (NSAID)	Headache, pain	No	90%
Benzo / Sedatives	Anxiety, pain, induce sleep	Partially	70%
Beta Blockers	Strong/fast heartbeat	Partially	40%

– – – – – – – – – – – – – – – – – – – – – – – – – – – – – –

Antiemetics (AE)​
What they do:	Move SN quick to intestine – fatal Reduce vomiting​
Do I need it?	No, but recommended. Many used SN fatally without AE Many vomited even with AE Could go either way. No definitive answer.
Are they available?	NO. Prescription only. Ask physician, example (original post) Search Internet Consult existing threads (others looking for it) Notes – Acquiring or importing prescription-only medication without a prescription is illegal. Antiemetics are not "restricted substance" but if caught may be fined (investigation unlikely). Forging prescription is a serious crime.
Warnings:	CAUTION. Meto & Prochlorperazine may cause problems. Must check contraindication to existing meds. Test small dosage (5mg) well before your ctb: Mild effects – try another small dose 8h later, or with painkillers (tolerance: less side effects) Severe effects – avoid.
Will any antiemetic work?	NO. Guide provides 6 AEs – only use those. Antiemetics: Must target dopamine (Domperidone, Prochlorperazine) Preferably serotonin as well (Metoclopramide)
Common antiemetics – short review	Prochlorperazine – ✓strongest dopamine blocker , no quick stomach emptying , high EPS risk Metoclopramide – ✓strong dopamine blocker , ✓ quick stomach emptying , moderate EPS risk Domperidone – ✓good dopamine blocker , ✓ quick stomach emptying , little EPS risk Domperidone is efficient as Metoclopramide for anti-vomiting (research)
Will X work as AE?​	If not in guide and you've searched threads, then NO. Don't use as antiemetics – Ondansetron/Zofran Diphenhydramine/Benadryl Dimenhydrinate/Dramamine Serotonin or Histamine only are not as effective. They don't promote gastric emptying. Read guide (AE by type – need dopamine antagonist)
What are "The 13 Antipsychotics"?	Replace AE completely – ONLY if part of your regular health treatment. Do not take a single dose; Do not change prescribed dosage. Personally-tailored – dosage varies greatly between individuals (explained here & here) If used regularly they replace AE – use Stat directions (without meto). Stan listed meds with nM (receptor affinity). Higher numbers may indicate stronger effects. Example .
Antiemetics – "Meto"​
Warnings:	Many are fine with it; some aren't; for a few poses a risk. Contraindications – SSRI, SNRI, TCAs, many anti-psychotics, and more. EPS effects – muscle spasms, jerky movements, tremors. EPS effects relieved with Diphenhydramine/Benadryl Members reported other effects(non EPS): "extreme unease in body, driving me crazy" "made me feel very ill, my whole body" "after taking meto went to sleep 4 hour" "throbbing headache"
Note – Prochlorperazine	Not Meto, but same warnings apply. Prochlorperazine has higher EPS risk
Why Meto preferred?	Only antiemetic that: Targets both dopamine and 5HT3, and Crosses into the brain This means: Strong stomach emptying effect Strong anti-vomiting vomiting effect However read "Do I need it"; alternatives (5) are fine.
Can strong effect achieved without Meto?	Ondansetron and Domperidone target peripheral receptors, not the brain (less side effects): Domperidone (Dopamine, less EPS) + Ondansetron (5HT3, less EPS) = Metoclopramide (Dopamine+5HT3 , Brain/EPS)
Bad Meto reaction – what to do?	Take Diphenhydramine/Benadryl 'Failing Meto' is fine, may: Use any of the other 5 on the list, or Ctb without antiemetics (many have but follow guide)
Antiemetics - Stat/Regimen​
What is it?	"Regimen/State" refers only to antiemetics. Two ways to take antiemetics: One single dose – Stat or Over 24h-48h – Regimen This may apply to N (consult guides).
Stat or Regimen?​	Both used with equal success. Depends on your sensitivities, conditions, and preferences.
Regimen –	Builds tolerance – reduces side-effects Increased effectiveness – accumulates (also) – increased stomach tone over time Comfortable – structured, feel prepared for ctb
Stat –	Efficacy appears similar with less hassle (no schedule) Less worry – like side effects during 2 days Comfortable – not demanding, no anxious wait, quick & simple
So, which should I choose?	Really up to you. Regimen came from PPH, for old/fragile/sick people. This may address you, could decrease discomfort. Stat is effective, great, easy option for many people. Taking it with benzo &
Antiemetics - Stat/Regimen Guidelines​
What are the dosages/schedule?	Read guide. Follow everything there. – This section intended only for details not in guide – .
Domperidone - Stat	Same as meto. Notes
Prochlorperazine – Stat	Smaller dosage – 10 to 20 mg Notes
Meto – Regimen	See guide. Schedule however more flexiblethan commonly published – Just take 3 a day over 24-48h morning lunch evening, 7-9h apart
Domperidone – Regimen	Same. Best to stick with it. Member was fine after trying 48h regimen x 20mg (instead of 10mg) Research concludes: Acummulation – "2 to 3-fold accumulation observed with repeated 4 times daily every 5 hr for 4 days." But only 3+ a day – "after two weeks of single 30mg per day peak plasma level almost same"
Prochlorperazine – Regimen	Same as Meto (10mg x 3 times a day) – but final dose smaller , like Stat Notes
Fasting – important?​	Yes, but flexible. Don't overdo it, follow your habits. 5h – Empty stomach, partially small intestines – Good enough. 8h – Empty most small intestines – Good. 12h – Long fasting not required (may cause discomfort). According to your habits/feeling; if you eat just twice a day, 12h fine.

– – – – – – – – – – – – – – – – – – – – – – – – – – – – – –

Acid-stuff​
What they do:	Stomach acidity May help SN absorption Stan detailed that process
Do I need those?	No. But many use these. Considered helpful, widely-available, cause little harm.
Are they available?	OTC / Internet Milk of Magnesia – widely available, just as effective. For other brands – search big sites
(1) Antacids
What they do:	Neutralizes acid on the spot
Known antacids:	Any antacid with magnesium hydroxide. Check any available OTC for ingredients with that. Milk of Magnesia.
Can I use other antacids?	We don't know. PPH pervioiusly recommended sodium bicarbonate, this was changed to acid-regulator.
(2) Acid-regulators
What they do:	Unlike antacids they reduce acid creation beforehand
Which should I use?	H2-receptor antagonists only
Which I should not use?	Proton pump inhibitors (PPI) do not work. Don't use them . Check medication ingredients and google to check if it's PPI .
What if I'm already taking acid-regulators?	If PPI used regularly, as part of health treatment – Continue your PPI as normal (don't use antacids or acid-regulators) . If PPI used occasionally – you can try to replace it with acid-regulators listed below (test it).
Known acid-regulators:	Cimetidine/Tagamet, Rantidine/Zantac, Famotidine
Can I use other acid-regulators?	No. May interfere with absorption.
Other Questions
Which should I use?	Either is fine, whatever you want.
Can I use antacids and acid-regulators together?	We don't know. Probably not good to mix.
Wiki says not to use acid-regulators	Stan recommended plain antacid, and gave acid-regulators which should work as well. The wiki reference was deemed incomprehensible (here, here, here)

Benzo / Sedatives​
What they do:	Reduce anxiety Reduce bad physical sensations Induce sleep
Do I need it?	No, many didn't use these at all But considered useful for anxiety and peaceful journey
Are they available?	Kinda. Prescription only – but very common In many places GPs prescribe benzo for many reasons.
Warnings:	Yes, though not harmful: Benzos effects vary greatly: Potency, tolerance, onset (how quick), duration (how long) change. Some benzo affects within 10m, others take 1h, and this changes individually Taken too soon – may fall asleep before SN. Test small dosage beforehand.
Which benzo to use? Is benzo X good?	Can't answer that. There are dozens. Anything that affects you more than 4h. Personally check this. Benzo "half-life" does not indicate long/short effects.
Other Sedatives​
Can I use opioids?	YES. But: Check contraindications Note anything of the opioid family significantly reduces: metabolism gastric emptying intestinal absorption May take twice the time.

Beta Blockers​
What they do:	Reduce fast strong heartbeat after SN May reduce possible headache These meds reduce blood pressure.
Do I need it?	No. Most people dont use it ; considered somewhat of luxury Some already use these, or find it easy to get due to prior conditions. Benzo/painkillers should help with sensations.
Are they available?	Prescription only. You should consult physician.
Which should I use?	Propanolol
Can I use others?	We don't know

Painkillers​
What they do:	Many experience moderate headache or general pain (rated 4/10): Helps headaches or pain
Do I need it?	No. But almost everyone use these. Considered helpful, widely-available, cause little harm.
Are they available?	OTC​
Which should I use?	Ibuprofen, or Paracetamol/acetaminophen
Can I use others?	Yes General NSAIDs that works for you Specific pain medication that works for you

 

[WhyIsLife56]

You could add that some of these drugs' availability can be different in some countries. Lik in the US, antiemetic is prescription only and some others you can get OTC.

 

[charlottewilts]

thank you for another one of these wonderfully formatted and info-packed FAQs! they're sure to be of much use to the newer members and older ones reconsidering their method alike. as @WhyIsLife56 suggested, availability varies greatly between countries, even cities in some cases. so it would probably be better to list the country you used as an example, followed by "may vary by location". i'd be very interested if you happen to stumble upon any additional info for beta blockers, too.

 

[Soulstax]

Thank you, this was a very necessary guide. I plan on taking SN without anything and trying to hold it down, but I don't tend to vomit easily.

 

[WhyIsLife56]

It would be cool if this could actually be part of the resources compilation or be pinned.
A lot of people come here asking if they can use SN without antiemetics so it would be useful if this thread (final draft) could be kept alive somehow :)

 

[Quarky00]

You could add that some of these drugs' availability can be different in some countries. Lik in the US, antiemetic is prescription only and some others you can get OTC.

availability varies greatly between countries, even cities in some cases. so it would probably be better to list the country you used as an example, followed by "may vary by location".

Appears 85% of members are from America or Europe, where Metos are Rx... And this is what I used.

Would be great if someone could elaborate on that. Could be confusing to say "varies", and hard to list countries. I don't know the specifics, so please, help !:)

 

[Shero]

This is really well arranged, thank you!

 

[WhyIsLife56]

Appears 85% of members are from America or Europe, where Metos are Rx... And this is what I used.

Would be great if someone could elaborate on that. Could be confusing to say "varies", and hard to list countries. I don't know the specifics, so please, help !:)

Antiemetic seems to be required with prescription in Australia as well other than the USA.

 

[nitrogen]

Benzos are likely difficult to get in the USA. I tried to get a benzo Rx from 3 primary care physicians and 1 psychiatrist. They all refused to prescribe it. Basically, benzos aren't the first line of treatment for insomnia and anxiety. This is what the psychiatrist wrote back:



Antiemetics prescriptions are super easy to get in the USA.
For meto, just say you have a cold, and suffer from indigestion/food stays in your stomach, your coughing bouts make you wanna vomit. For ondansetron, say you suffer from food poisoning, feel nauseated and you vomit.

Like I pointed out in another thread, meto isn't quite domperidone plus ondansetron. Meto is a very potent dopamine receptor antagonist, but it only becomes a non-selective 5HT3 receptor antagonist at high dosage; whereas ondansetron being a selective 5HT3 antagonist is highly specific for the 5HT3 receptor. In other words, meto is not as potent a 5HT3 antagonist as ondansetron. The antiemetic regimen (for inducing coma, but should also applies to SN and N) that the Canadian Association of Medical Assistance in Dying Assessors and Providers recommends is meto PLUS ondansetron.

Here's the link to the document: https://camapcanada.ca/wp-content/uploads/2019/01/OralMAiD-Med.pdf

@Quarky00 Thank you so much for compiling this FAQ. It's very well organized and succinct. You've clearly done a lot of research on this topic. I don't mean to be argumentative or judgmental; I just wanna supplement your already comprehensive guide a bit. I wouldn't be able to put out a better FAQ.

 

[nitrogen]

Hey mothafakas/sweethearts/SS members!!!

I thought when it comes to SN, everybody has something to say or ask?

Why the fuck are you all mute today?

Clearly @Quarky00 put in a tremendous amount of time and sweat into making this neat SN FAQ resource for everyone. I can't believe this thread has disappeared from the first page on the first day of its posting while the threads of lazy people who don't bother to use a search bar asking stupid SN questions that have been answered 100 times get more attention.

 

[WhyIsLife56]

Hey mothafakas/sweethearts/SS members!!!

I thought when it comes to SN, everybody has something to say or ask?

Why the fuck are you all mute today?

Clearly @Quarky00 put in a tremendous amount of time and sweat into making this neat SN FAQ resource for everyone. I can't believe this thread has disappeared from the first page on the first day of its posting while the threads of lazy people who don't bother to use a search bar asking stupid SN questions that have been answered 100 times get more attention.

View attachment 24598

Lol
Someone needs to bump this thread every now and then.

 

[Time]

Good job, Quarky00.

 

[AlreadyGone]

Great job!! Clear and concise. Thanks!

 

[TimeToBiteTheDust]

This is OK.Thanks a lot

 

[jgm63]

Good job.....

 

[Delia]

Amazing job as always, made me realize I had the wrong "anti-acids", well fuck me :')

 

[aloneintheworld]

I am confused about the anti acid isn't milk of magnesia a laxative? Also which would be better Zantac or Pepcid low key confused over what is the best option

 

[Letmego. Please]

Do we still need to keep reminding the nippers that Cannabis doesn't constitute a usable anti emetic?

Oh & bump......

 

[zeroambition]

Great job!

 

[Quarky00]

This FAQ is so long it requires a FAQ of its own

1. Direct Members
Members are in distress, hard to concentrate, vast resources here, and many are new or quick to share their thoughts and concerns.
Rather than bumping, it could be beneficial just to point them in the right direction:

• If member asks a question – one can reference the relevant section.
• Example , though not a good one (I spoon fed rather than directed).
• Example 2, again spoon fed.. instinct, can't control that :P

Unlike a guide, FAQ can do exactly that, provide a quick reference.
Helps both the one asking, and the one answering.
This was the reasoning behind the 'specification sheet' format.

2. Split FAQ
Considering (1), along with interest that emerged, and after some thought about accessibility, I think AE should have their own FAQ, with "Further Reading".
Therefore this FAQ should be divided to two separate FAQs – as Benzo-Acid-etc are rather short and simple.

3. Improve Readability
Could be some table of content (more a wiki feature), or better styling of headlines.
Make it more readable and easily locate a section/subject.

Hey mothafakas/sweethearts/SS members!!!
I thought when it comes to SN, everybody has something to say or ask?
Why the fuck are you all mute today?
. . .

LOL!
Salesperson of the year award
@nitrogen, argumentative or judgmental?! Quite the opposite, really appreciate
Your benzo experience surprised me, but I then recalled stuff. It's not indicative, will explain later. Meto discussion very interesting.

 

[Quarky00]

@nitrogen ,

Benzo – Availability

I wouldn't generalize your experience. Your physician sounds very attentive and skilled (rare); Xanax is extremely despised (others ok); benzo not common for mild--moderate insomnia; benzo still one of the most prescribed (big time); APA's only first line treatment for immediate relief of panic attack. There's also the benzo controversy, some reluctant to prescribe.

Benzo accessibility was also in context to members here. Many already have it (conditions, family or friends, etc). Many can easily get it by describing their existing insomnia/panic (debilitating) to physician. Last but not least, almost any benzo would do – compared to one specific AE needed out of dozens.

However you've raised a good point – AE shouldn't be portrayed as hard to get (suggested changes at the end).

Suggested changes:

Are they available?

Kinda. Prescription only – but very common In many places GPs prescribe benzo for: Severe insomnia Panic attacks – immediate relief Anxiety – add-on therapy Temporary, occasional, PRN – "wanna try 5"

Other Sedatives
Can I use Z-drugs?	Yes, same as benzo.

- - - -

Meto

Great points there, as always. Important and interesting read. First and foremost – any Q&A that could be added to FAQ (how to phrase)?
Or perhaps better to add 'extra info' section... Idk. What say you.

Efficacy & Affinity

Meto=Ond+Dom! Wanted to mention that in so many threads, but thought it would confuse, or regarded as minutia. There's more to it than receptor affinity or selectivity. In addition to what you wrote:

• In that context (receptors), 5HT3 antagonists are more potent than Meto. But their sites of action are different – Ond in stomach, Meto all over.
  • As a note, being a selective antagonist (local or specific) could be a pro or a con. Hence systematic broad AE, targeting both CTZ (brain) and stomach, plus prokinetic. "One pill to rule them all".
• Meto not that weak: Ondestron 5HT3A potency ~ 8.0 , Metoclopramide ~ 6.0 . See here.
  • I know it's significant but is it crucial? I don't know.
• They could actually complement, as you and k75 suggested. May enhance AE effects, could change common practice (more feedback required).
• Overall Meto vs 5HT3 antagonists is not such a big medical question, depends on patient, conditions, practice, etc. CINV, poison, pre-op etc. Affinity is indicative, but in terms of efficacy all three considered similarly effective.

Another interesting point: "non-selective 5HT3 receptor antagonist at high dosage". Regimen exceeds max daily dosage – actually doubling it to 60mg daily. Overall Regimen accumulates to rather high peak – up to 45mg. Is that enough? Does it work? I don't know.

Meto discussions go neither here nor there in terms of bottom line. Though theoretically interesting and enlightening :)
Well said -- no 'one size fits all'..

Availability

Touched a bit on that in the benzo notes. In comparison, AEs are not a serious substance, but also not common. Due to anxiety many prefer online pharmacy, and I don't want to say it's okay. Any suggestions how to change that text would be great. :)

Suggested changes:

Are they available?

No. Prescription only, but many have acquired AE with little trouble: Easy to ask a physician – example (original post) Search Internet Consult existing threads (others looking for it) Notes – Acquiring or importing prescription-only medication without a prescription is illegal. Antiemetics are not "restricted substance" but if caught may be fined (investigation unlikely). Forging prescription is a serious crime.

 

[WhyIsLife56]

Might as well link this too, just in case if anyone ever wants to use it for research purposes

https://sanctioned-suicide.net/threads/1-week-dietary-supplement-regimen-sn.25744/

 

[Quarky00]

Couldn't really figure how to insert it.

• Not part of absorption, went with toxicity. Should be "increased anemic state" (not layman's term)
• The biochemistry is there, but on small scale. Did not see resource I could add about effectiveness, or many people that had tried it.

But, if the goal was to direct people to explore more options – I think this would be adequate.

	Function	Hard to get	How often used with SN (very rough estimate)
Better SN intake
Antiemetics (AE)	Stomach emptying, anti-vomiting	Yes	70%
Antacid / Acid-Reducers	May improve absorption	No	80%
Dietary Supplements	Sustain blood toxicity	No	30%
Ease symptoms
Painkillers (NSAID)	Headache, pain	No	90%
Benzo / Sedatives	Anxiety, pain, induce sleep	Partially	70%
Beta Blockers	Strong/fast heartbeat	Partially	40%

~

Now, you suggested adding a link, I went full monty – new table ;)
It's really nice to have. But is it required? Up to you, the dietary table could: (1) be redundant, link suffice; (2) simplified/shortened; (3) kept as it is.

Dietary Supplements​
What they do:	Sustain high levels of blood toxicity after SN absorption
Do I need it?	No, many didn't use these, but widely-available and could hasten fatality
Are they available?	Yes. Phytic acid supplement Almonds (copious amounts) during 1 week before SN – not roasted
How does it work?	SN makes blood cells go "bad" – metHb (no oxygen). Body naturally fixes dysfunctional blood Phytic acid stops that process (inhibits Methemoglobin Reductase) Lack of oxygen to tissues should occur faster Notes

 

[WhyIsLife56]

I read somewhere (an Amazon review) that inositol hexaphosphate (IP6) and inositol should be used together for maximum effect.

 

[WhyIsLife56]

I just found a website regarding how to take the Phytic acid supplement (inositol hexaphosphate). It mentions that you take IP6(inositol hexaphosphate) with inositol together.

IP-6 and Serum Iron

IP-6 - One of the key biomarkers is the level of iron in the blood. Of course, iron can be normal, high or low. It is vital to the health of each person to keep that iron in an ideal range. Too low and we will either be looking at lack of dietary iron, absorption problems or loss from bleeding...

www.ovitaminpro.com

 

[SpaceForGrace]

Hi. In my location I can buy AE metoclopramide hydrochloride. Is that ok?

 

[Letmego. Please]

Other SedativesCan I use Z-drugs?Yes, same as benzo.

I wouldn't be so quick to compare effects, all Z drugs are hypnotics rather than true sedatives (as are a number of Benzo's in higher doses but my brain nots working that well at the mo)

As such even in prescribed doses let alone higher which amplifies the effects they are well know to cause Parasomnia where a person is likely to engage in activities while completely unaware due to them being Hypnotic's not sedatives.

There are many tales of woe written on various forums about mixing up taking Hypnotics, expecting a sedative effect only to 'wake' up to find they were actively doing things while 'asleep'
So I can forsee a problem of folks taking a handful for the above reasons of suicide only to find they then phoned/went for a walk/got in a car & drove etc And its not something that we here would find helpful.

I could link to many such misadventures on Erwoid & the like but I haven't had enough coffee yet Sorry @Quarky00. will try better next time but thought it important to highlight the vast difference in true sedatives & Z Drugs & some Benzos.

@Quarky00 if I get around to doing the Benzos that are hypnotics rather than true Benzos & as such may cause issues it might be tidier if I Pm you rather than clogging up this resource with too many conflicting replies, but will only Pm you if you say its ok as it seems rude otherwise lol

 

[Quarky00]

As such even in prescribed doses let alone higher which amplifies the effects they are well know to cause Parasomnia where a person is likely to engage in activities while completely unaware due to them being Hypnotic's not sedatives.

There are many tales of woe written on various forums about mixing up taking Hypnotics, expecting a sedative effect only to 'wake' up to find they were actively doing things while 'asleep'. So I can forsee a problem of folks taking a handful for the above reasons of suicide only to find they then phoned/went for a walk/got in a car & drove etc And its not something that we here would find helpful.

True about Z-drugs in general. But this is not general usage....

SN Faint + Sleeping Pill– unlikely to drive ;)

Z-Drugs vs. Benzo

Zolpidem – "Zolpidem is a nonbenzodiazepine Z drug which acts as a sedative and hypnotic."
Sedative – "Iinduces sedation by reducing irritability or excitement. CNS depressants. Produce beneficial relaxing effects by increasing GABA activity."
Z-drugs have fewer of the full desirable effects, compared with those of benzos –

• sedative
• hypnotic (sleep-inducing)
• anxiolytic (anti-anxiety)
• anticonvulsant
• relaxant (muscles)

Z-Drugs Example

Using zolpidem (not extended-release) after tested (per FAQ) – you know it makes you sleepy in 10 minutes, and fall asleep in 15 minutes. You should take your zolpidem, and 3-5m later SN:

• 00:00 - Z
• 00:05 - SN .... estimate your timeframe of possible side-effects:
  • 00:05 - 00:15 .. Vomit
  • 00:15 - 00:25 .. Fainting
• 00:10
  • SN headache, but -
  • Drowsiness (Z) ✓
• 00:12
  • Vomit
  • 2nd serving
• 00:15
  • Sleep (Z) ✓
  • Faint (SN) ✓
  • --> Incapacitated ✓
• 00:25 - Unconsciousness (SN)..

Unlikely to make phone calls there.

Revision

Warnings:

Yes, though not harmful: Benzos effects vary greatly: Potency, tolerance, onset (how quick), duration (how long) change. Some benzo affects within 10m, others take 1h, and this changes individually Taken too soon – may fall asleep before SN. Test small dosage beforehand. Avoid extended-release – they act too slow

Other Sedatives
Can I use Z-drugs?	Yes, same as benzo, but: More drowsiness, may fall asleep – test first Reduce physical sensations Anxiety - mild to moderate reduction (benzo more powerful here)
Can I use other 'sleeping pills'?	No. You need GABA sedatives. Antihistamines, Herbals, OTC – won't work. Others – we don't know – use at your discretion Real anesthetics Ketamine (member used)
Can I use other sedatives?	Perhaps real anesthetics, we don't know – be cautious! Little to no information about using anesthetics with SN Propofol – dangerous – may cause respiratory arrest Ketamine – considered safe – member used

–––––––––––––––––––

I just found a website regarding how to take the Phytic acid supplement (inositol hexaphosphate). It mentions that you take IP6(inositol hexaphosphate) with inositol together.

Good information. It's currently a niche practice that should be explored and tested more. We can look for members that used it, or planning to use it? This may justify its own conversation or guide.

 

[Daniela]

Both dopamine blockers and histamine 2 blockers trigger prolactin release i.e. you may stop menstruating for a while.

Granted, it doesn't matter if you're going to die. But it may be something you want to know if 1. you're just taking tests 2. don't go through with it for whatever reason 3. are planning the attempt around your period

 

[WhyIsLife56]

I plan on using the supplements but there were more people who used almonds instead of supplements.