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Valhala

Valhala

Arcanist
Jul 30, 2024
429
Let's assume this "works" and is probably even faster and more comfortable than N - I don't doubt it, however; Propofol is hardly easier to obtain than N (perhaps for a nuance, but it is still quite demanding) and most importantly, this procedure is technically too complicated for most people - more complicated than the inert gas method. I doubt that someone who is a layman in the field would medical profession, decided on this method even if he managed to acquire all of the above.
 
summersolstice101

summersolstice101

Member
Jan 12, 2025
28
1000mg without an IV line .. I doubt it.
Yea it only works with an IV line.

Let's assume this "works" and is probably even faster and more comfortable than N - I don't doubt it, however; Propofol is hardly easier to obtain than N (perhaps for a nuance, but it is still quite demanding) and most importantly, this procedure is technically too complicated for most people - more complicated than the inert gas method. I doubt that someone who is a layman in the field would medical profession, decided on this method even if he managed to acquire all of the above.
Agreed that propofol can be extremely difficult to obtain, especially in tough places like Australia, it is a highly restricted medication.
However, OP does mention that there is a source with Russian pharmacies - I haven't personally checked if they can deliver through stringent Aus customs , but I think this is lead worth exploring for those that perform the procedure.

Also I see where you're coming from that this may not be the best approach for the layman.
I think for those people confident with medical literacy, and manual dexterity, this could be a useful alternative.
 
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Valhala

Valhala

Arcanist
Jul 30, 2024
429
Yea it only works with an IV line.


Agreed that propofol can be extremely difficult to obtain, especially in tough places like Australia, it is a highly restricted medication.
However, OP does mention that there is a source with Russian pharmacies - I haven't personally checked if they can deliver through stringent customs, but I think this is lead worth exploring for those that perform the procedure.

Also I see where you're coming from that this may not be the best approach for the layman.
I think for those people confident with medical literacy, and manual dexterity, this could be a useful alternative.
I agree with you, I wrote something similar. If there is availability of Propofol at Russian clearnet pharmacies, that is certainly good news.
 
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Y

youpi

Member
Jul 4, 2024
47
You guys need to stop worrying about customs with the exception of a few country like Australia and some others, most things will pass.
 
Amarajoy

Amarajoy

Experienced
Sep 12, 2024
291
Fantastic

Really appreciate your post, this is fantastic work.
The fact that this is the method of choice by anesthesiologists speaks volumes to it's efficacy.

Many people have have commented concerns about the technicalities of the setting up an IV line. I understand that it may be extremely difficult for some to perform, and IV route can be restrictive in these ways. For those that are keen to learn and committed to this method, there are many sources online (even on youtube) which explain it step-by-step. If you are unable to find any videos or don't understand parts of it, feel free to message me and I can explain or provide some materials that can guide you.
Trying to get over the fear of sticking myself for the IV is my major hurdle.
 
summersolstice101

summersolstice101

Member
Jan 12, 2025
28
Trying to get over the fear of sticking myself for the IV is my major hurdle.
If the problem is the pain associated with getting jabbed, then it's not commonly used in adults, but you can try to numb the area - try topical anaestehtic creams, or try injecting some local anesthetic through a smaller needle over your site (but downside is it the fluid can make it more difficult to see the vein).
If it's a needlephobia, this is a bit more difficult to overcome, but it's all about exposure therapy, which is easier said than done. Start with looking at photos, then videos, then handling the equipment in person, trying on dummies, all that before trying on yourself.
 
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Amarajoy

Amarajoy

Experienced
Sep 12, 2024
291
If the problem is the pain associated with getting jabbed, then it's not commonly used in adults, but you can try to numb the area - try topical anaestehtic creams, or try injecting some local anesthetic through a smaller needle over your site (but downside is it the fluid can make it more difficult to see the vein).
If it's a needlephobia, this is a bit more difficult to overcome, but it's all about exposure therapy, which is easier said than done. Start with looking at photos, then videos, then handling the equipment in person, trying on dummies, all that before trying on yourself.
Thank you. Yes, it's the needle phobia for me. I can't watch when someone else does it so attempting it in myself seems pretty impossible at this point.
 
G

G50

Member
Jun 28, 2023
74
Absolutely. In my country, lidocaine injection before propofol is standard procedure.
And if I want to make the propofol method fail proof, it will not be KCL. I put an airtight bag over my head that prevent me from breathing. In this way, even 200-300mg of propofol would be enough. Of course, this also depends on factors such as age, drug addiction, weight. More propofol may be needed. For the average person with naive GABA receptors, the anesthesia induction dose is enough.

I am thinking about combining a propofol injection with a debreather apparatus I made. This apparatus cost me less than about $60 to make.

The propofol would just be to create unconsciousness while the debreather deprives you of oxygen

My debreather worked fine in terms of removing the carbon dioxide from the expelled breath, but I found even though the CO2 was removed from the air I was breathing, as oxygen levels went down in the debreather, and my blood oxygen saturation reached 70%, I had a strong compulsion to breathe fresh air.

I thought that once you removed the CO2, you would not have any compulsion to breathe as the oxygen goes down, but I found this is not the case.

Someone on my thread pointed out (in this post) that the body senses high blood CO2 which creates an urge to breathe (hypercapnic drive), but also the body senses low blood oxygen (hypoxic drive), and this also causes an urge to breathe.

So I realised that it would not be possible to use my debreather without taking some drug to make you unconscious, or some drug which is a respiratory depressant, so suppresses the hypoxic drive. Propofol is a respiratory depressant, so might even work in combination with my debreather apparatus even if you are not fully unconscious. If self-injecting propofol to the point you lose consciousness, this I hope would give you enough time in the unconscious state for the debreather to do its job.
 
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E

Endofpain

Student
Dec 21, 2024
109
Does anybody know where to get propofol? A dm would be greatly appreciated. I have found a russian online pharmacy that is legit. The problem is that they dont ship to my country...
 
Sunset Limited

Sunset Limited

I believe in Sunset Limited
Jul 29, 2019
1,345
I am thinking about combining a propofol injection with a debreather apparatus I made. This apparatus cost me less than about $60 to make.

The propofol would just be to create unconsciousness while the debreather deprives you of oxygen

My debreather worked fine in terms of removing the carbon dioxide from the expelled breath, but I found even though the CO2 was removed from the air I was breathing, as oxygen levels went down in the debreather, and my blood oxygen saturation reached 70%, I had a strong compulsion to breathe fresh air.

I thought that once you removed the CO2, you would not have any compulsion to breathe as the oxygen goes down, but I found this is not the case.

Someone on my thread pointed out (in this post) that the body senses high blood CO2 which creates an urge to breathe (hypercapnic drive), but also the body senses low blood oxygen (hypoxic drive), and this also causes an urge to breathe.

So I realised that it would not be possible to use my debreather without taking some drug to make you unconscious, or some drug which is a respiratory depressant, so suppresses the hypoxic drive. Propofol is a respiratory depressant, so might even work in combination with my debreather apparatus even if you are not fully unconscious. If self-injecting propofol to the point you lose consciousness, this I hope would give you enough time in the unconscious state for the debreather to do its job.
Propofol does not inhibit respiration in subanesthetic doses. You can inject yourself with enough propofol before you become unconscious. If you have IV experience. The anesthesia induction dose of propofol is 2.5 mg/kg without premedication.
 
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Csmith8827

Csmith8827

Don't you listen to your heart? (Listen to it...)
Oct 26, 2019
940
Can you test propofol to make sure its legit? Like its the real thing? And where do i buy such a test? And when i hook up the iv how much do i need? Can someone please explain the iv injection? And what happens if it doesnt work? Are there any side effects to a failed attempt?
 
Eudaimonic

Eudaimonic

I want to fade away.
Aug 11, 2023
829
I am thinking about combining a propofol injection with a debreather apparatus I made. This apparatus cost me less than about $60 to make.

The propofol would just be to create unconsciousness while the debreather deprives you of oxygen

My debreather worked fine in terms of removing the carbon dioxide from the expelled breath, but I found even though the CO2 was removed from the air I was breathing, as oxygen levels went down in the debreather, and my blood oxygen saturation reached 70%, I had a strong compulsion to breathe fresh air.

I thought that once you removed the CO2, you would not have any compulsion to breathe as the oxygen goes down, but I found this is not the case.

Someone on my thread pointed out (in this post) that the body senses high blood CO2 which creates an urge to breathe (hypercapnic drive), but also the body senses low blood oxygen (hypoxic drive), and this also causes an urge to breathe.

So I realised that it would not be possible to use my debreather without taking some drug to make you unconscious, or some drug which is a respiratory depressant, so suppresses the hypoxic drive. Propofol is a respiratory depressant, so might even work in combination with my debreather apparatus even if you are not fully unconscious. If self-injecting propofol to the point you lose consciousness, this I hope would give you enough time in the unconscious state for the debreather to do its job.
Maybe I'm misunderstanding, but why couldn't one just inhale the gas and breath-hold until they passed out from hypoxia?
 
D

David753

Member
Jan 29, 2025
12
Да, это работает только с внутривенной линией.


Согласен, что пропофол может быть чрезвычайно трудно достать, особенно в таких неблагополучных местах, как Австралия, это крайне ограниченный препарат.
Однако автор статьи упоминает, что существует связь с российскими аптеками — я лично не проверял, могут ли они осуществлять доставку через строгую австралийскую таможню, но думаю, что тем, кто выполняет эту процедуру, стоит изучить эту информацию.

Я также понимаю, что это может быть не лучшим подходом для неспециалиста.
Я думаю, что для людей, обладающих медицинской грамотностью и ловкостью рук, это может стать полезной альтернативой.
Да, в России он продается, называется анестофол.
интересный способ
 
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D

David753

Member
Jan 29, 2025
12
Hi.Yes it is 500mg/10ml and don't forget there is 500mg lidocaine too.

If we are talking about propofol, slow infusion is bad idea because it will be metabolised very fast. Bolus dose is better with 20-25cc of Anestofol. 1000mg propofol + 1000mg lidocaine is lethal for everyone.

Can you share your Anestofol resource via PM with me?
Tell me please.How fast is it better to inject anesthofol using a syringe pump?
 
Sunset Limited

Sunset Limited

I believe in Sunset Limited
Jul 29, 2019
1,345
Tell me please.How fast is it better to inject anesthofol using a syringe pump?
Sorry but this is more complicated than you think. We have discussed it in this thread before. Anestofol contains lidocaine but it takes 30 seconds for lidocaine to work. There is high concentration of phenol. Phenol is an irritant. Even an induction dose of medical use 1% propofol (even if administered slowly) will cause pain. 5% anestofol will probably burn the veins like hell. making it impossible to push a 20cc bolus dose.

So an infusion is needed. A drip infusion setup or an infusion pump. For someone who has no IV experience, placing a cannula, drip infusion setup, infusion pump management is not really realistic. If you have IV experience, a drip infusion will work. The maximum flow rate you can get from a gravity fed drip infusion is 8-9cc/min. Infusion pump is better option ofc.
 
D

David753

Member
Jan 29, 2025
12
Извините, но это сложнее, чем вы думаете. Мы уже обсуждали эту тему. Анестофол содержит лидокаин, но для действия лидокаину требуется 30 секунд. В нем высокая концентрация фенола. Фенол является раздражителем. Даже индукционная доза медицинского применения 1% пропофола (даже если вводится медленно) вызывает боль. 5% анестофол, вероятно, обожжет вены как в аду. изготовление невозможным введением болюсной крышки 20 куб. см.

Итак, инфузия необходима. Установка для капельной инфузии или инфузионного насоса. Для человека, у которого нет опыта внутривенного вливания, установка канюли, установка капельной инфузии, управление инфузионным насосом не совсем реалистичны. Если у вас есть опыт внутривенного вливания, подойдет капельная инфузия. Максимальная скорость потока, которую вы можете получить от капельной инфузии с гравитационной подачей, составляет 8-9 куб. см/мин. Инфузионный насос, конечно, лучший вариант куба. см/
I didn't put it right, I meant the infusion pump. I'm writing through a translator. If I suddenly call a nurse at home to insert a catheter, then I will attach a hose to it myself. I think I'll figure out how to set up the pump. I'm just collecting information for now. So how fast is it better to inject anesthofol through a pump?
 
sevennn

sevennn

Wizard
Sep 11, 2024
615
I didn't put it right, I meant the infusion pump. I'm writing through a translator. If I suddenly call a nurse at home to insert a catheter, then I will attach a hose to it myself. I think I'll figure out how to set up the pump. I'm just collecting information for now. So how fast is it better to inject anesthofol through a pump?
может глупый вопрос/ но чтобы вызвать медсестру для поставки канюли не нужно направление от врача? везде где я смотрю на эту тему в интернете пишут подобное. типа разве ее поставят просто так потому что вы попросите? у меня нет опыта в вызове медсестры на дом просто
 
D

David753

Member
Jan 29, 2025
12

может глупый вопрос/ но чтобы вызвать медсестру для поставки канюли не нужно направление от врача? везде где я смотрю на эту тему в интернете пишут подобное. типа разве ее поставят просто так потому что вы попросите? у меня нет опыта в вызове медсестры на дом просто
In Russia, you don't need a referral for this.I already asked where I got the tests, will you put a catheter in me, they said yes.
 
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E

Endofpain

Student
Dec 21, 2024
109
This is the best method for me. I prefer it over N. The problem is that you cannot source propofol anywhere
 
Sunset Limited

Sunset Limited

I believe in Sunset Limited
Jul 29, 2019
1,345
I didn't put it right, I meant the infusion pump. I'm writing through a translator. If I suddenly call a nurse at home to insert a catheter, then I will attach a hose to it myself. I think I'll figure out how to set up the pump. I'm just collecting information for now. So how fast is it better to inject anesthofol through a pump?
As fast as possible. Fastest infusion pump that I know, 20cc/min. They are not made for fast bolus. I think you need 3 x anestofol vial it is totally 3 grams of propofol but don't forget 10cc wil remain in the IV line. So 20cc will be infused totally 2 grams of propofol. Better than 1 gram. It provides more guarantee.
 
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sevennn

sevennn

Wizard
Sep 11, 2024
615
i have the stuff with me btw. it looks very clear in the bottle. not milky looking at all. is it cus the lidocaine is mixed in with it?
 
D

David753

Member
Jan 29, 2025
12
As fast as possible. Fastest infusion pump that I know, 20cc/min. They are not made for fast bolus. I think you need 3 x anestofol vial it is totally 3 grams of propofol but don't forget 10cc wil remain in the IV line. So 20cc will be infused totally 2 grams of propofol. Better than 1 gram. It provides more guarantee.
Then I need 5 vials of anestofol. There are 0.5 grams of propofol in one bottle.
 

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Sunset Limited

Sunset Limited

I believe in Sunset Limited
Jul 29, 2019
1,345
i have the stuff with me btw. it looks very clear in the bottle. not milky looking at all. is it cus the lidocaine is mixed in with it?
So propofol is not emulsified. There is just oil. If you inject oil, it causes oil embolism but if this is an euthanasia it doesn't matter. No emulsion is needed. They combined propofol and lidocaine in oil.
Then I need 5 vials of anestofol. There are 0.5 grams of propofol in one bottle.
I think 6 vials is better. 50 cc in syringe + 10 cc in IV line. totally 50 cc will be infused.
 
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DontTouchMeImFamous

DontTouchMeImFamous

Member
Jul 18, 2024
72
this is really interesting. CBT using veterinarian euthanasia drugs has been in my mind since forever. Veterinarian drugs are largely unregulated in where I live but they are almost bever sold at pharmacies. They are exclusively available at vet clinics. The problem is what am I supposed to tell the vet to get it without raising suspicion? For the life of me, I couldn't dare to ask for it.
Yeah, I don't know how but someone found out that I had it (probably my therapist, who I told a while back) and the police just showed up at my door.
wow what a traitor b*tch. I'm so sorry for you.
 
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