Go to college, get a PHD in like brain chemistry or something, and research the topic until you find an answer.
Based off of reality, that's how someone would find out something like this. Too think you just going to stumble upon some groundbreaking new form of partial lobotomy is one of the most unrealistic things I've ever heard.
Things like this takes countless hours of research conducted by countless people. Why don't you look into what it actually takes to make a scientific breakthrough.
That's the only way you're going to figure this out, so if it's really that important to you, get studying