Help does propranolol make you pass out faster sn

[peewee]

i know the beta blockers will stop the heart from racing, but i think i saw somewhere it makes you pass out faster due to lowering blood pressure ? ive also seen in one PPH to take 400mg, and another says 800mg, which is it?
ive also just read it can slow death though by putting off cardiac arrest, but i thought death was caused by hypoxia, this is confusing - i would rather pass out quick and dont really like the idea of having a racing heart

 

[what]

the tachycardia will make your heart beat faster because you are depraved of oxygen thats your body's mechanism of trying its best to supply more oxygen but with propranolol that wont happen so you will indeed black out earlier from oxygen depravation

 

[Macedonian1987]

Would mixing propranolol, benzos and meto have some sort of bad interaction among themselves. Like making me more nauseated or too lethargic?
When I drink my SN I will be using benzos and meto, but i'm having second thoughts about throwing in propranolol in the mix.

 

[what]

Would mixing propranolol, benzos and meto have some sort of bad interaction among themselves. Like making me more nauseated or too lethargic?
When I drink my SN I will be using benzos and meto, but i'm having second thoughts about throwing in propranolol in the mix.

no those 3 medication will generally not make you nauseous but if you fasted for too long nausea generally increases so you have to be careful

 

[peewee]

no those 3 medication will generally not make you nauseous but if you fasted for too long nausea generally increases so you have to be careful

would stat dose be better then? im also confused about antiacids and which are the best to take - i want to avoid stomach pain which i think antiacids can help with - my protocol will include meto, alprozolam, paracetamol, propronalol and some kind of antiacid - could you advise if this is ok, and which antiacid is best? ive seen alot on PPI/H2 blocker/regular anti acid - i just want to do whatever will result in least discomfort

 

[nobodycaresaboutme]

Nothing is proven about beta blockers like propranolol. I doubt that propranolol can make SN protocol smoother.

From PPH 2025

Antacid & B Blocker Use

There has been debate about the importance of lowering stomach acid (in order to lessen gastric nitric oxide production with the associated drop in blood pressure) vis a vis allowing more nitrite to be directly absorbed into the blood from the small intestine.

However, the benefit (in terms of potentiation) of taking an
antacid such as Mylanta, an H2-antagonist such as Cimetidine or a proton pump inhibitor (PPI) such as Nexium, cannot be clearly established. This is no longer advised.

B-blockers Controversy

It has also been argued that sodium nitrite can be made more lethal by the concurrent administration of a B-blocker like propranolol. It is argued that because there is a compensatory cardiac response to nitrite-induced cerebral hypoxia in the form of an increased heart rate (tachycardia) as well as an increase in cardiac output, the B-blocker will frustrates this, It will also prevent tachycardia and speed death. A dose of 400mg of propranolol taken with the antiemetic (metoclopramide) has been advised.

Some reports have suggested that while the use of a B-blocker may alleviate the uncomfortable sensation of a racing heart (tachycardia) before LOC, its use may also prevent the increased oxygen demand ofthe heart and slow death from cardiac arrest. Until more information is available, the benefit (or otherwise) of using a B-blocker cannot be established.

 

[peewee]

Nothing is proven about beta blockers like propranolol. I doubt that propranolol can make SN protocol smoother.

From PPH 2025

for reducing tachycardia is my only concern which it should do hopefully

 

[nobodycaresaboutme]

for reducing tachycardia is my only concern which it should do hopefully

Indeed propranolol slows the heart rate. I think taking the medication won't ruin your entire protocol and rather it's good in order to gain the feeling of security that tachycardia is controled. On the other hand unknown variables might be added by propranolol use. I just wanted to mean that the claim beta blockers work with SN is not backed up.

 

[peewee]

Indeed propranolol slows the heart rate. I think taking the medication won't ruin your entire protocol and rather it's good in order to gain the feeling of security that tachycardia is controled. On the other hand unknown variables might be added by propranolol use. I just wanted to mean that the claim beta blockers work with SN is not backed up.

yea for sure, i suppose im going of that many ppl have ctb taking propranolol with sn, so im going to risk it - im concerned severe tachycardia might make me call for help, so will include it in my protocol. same goes for anti acid - i know its not recommended anymore, but there is a chance it can revent/reduce stomach pain, so i will take it too x

 

[unluckysadness]

This question bothers me a lot too. I really hope that we can get some new informations in the next PPH version. My biggest fear is these 12-15 minutes (maybe more) because I know I could call for help if I panic because of fast heartbeats so I plan to take propranolol.

 

[peewee]

yea

This question bothers me a lot too. I really hope that we can get some new informations in the next PPH version. My biggest fear is these 12-15 minutes (maybe more) because I know I could call for help if I panic because of fast heartbeats so I plan to take propranolol.

yea exactly - in the successful cases doc many ppl use propronalol and succeed - pain and tachycardia are the 2 things that can cause panic and lead to calling for help, so at least with a beta blocker 1 can for sure be avoided - i also believe from my reading that taking anti acid may reduce stomach pain, so i will do that do , i have access to nexium , im assuming thats ok to take with everything? idk if it has interactions with meto....will also use a large dose of xanax. i read somewhere that purity of the sn may explain pain , that lower purity may result in higher chance of pain do to more nitrates. i also dont know if the 48 hour protocol is best or stat dose, hard to know

 

[what]

would stat dose be better then? im also confused about antiacids and which are the best to take - i want to avoid stomach pain which i think antiacids can help with - my protocol will include meto, alprozolam, paracetamol, propronalol and some kind of antiacid - could you advise if this is ok, and which antiacid is best? ive seen alot on PPI/H2 blocker/regular anti acid - i just want to do whatever will result in least discomfort

while the use of antacids/PPI/H2 blocker have been proven to lessen both stomach pain & nausea (even DRASTICALLY when done properly), the founder of exit international, dr. nitschke, tells us it will increase the amount of time it takes to lose consciousness, and therefore no longer advises it.

however, both of these claims do not contradict eachother can and still overlap. once we take both of them into account, we get 1 conclusion; the use of PPIs and antacids will lessen pain and nausea, but at the cost of increasing the time it takes for loss of consciousness.

generally taking just antacids is not enough. if you want to truly minimize this kind of pain - and im talking LITTLE TO NO PAIN/NAUSEA, this is what you do:

take a daily morning dose of 40mg of esomeprazole (PPI) for 7 whole days before the SN drink. the SN drink day is included, and so it should be the 7th day of the esomeprazole regime.

its important to note that for esomeprazole, as a PPI that slowly blocks the acid producing pumps in your stomach lining unlike antacids that just neutralize your stomach acid for a few hours, you need an empty stomach for it to work effectively. this means taking the daily dose preferably right after you wake up, ATLEAST 5 hours before your first meal.

administering an antacid will also increase the effectiveness, you take 1000mg of calcium carbonate (2 TUMS or 1 'super-strength' TUM) 15 minutes before the SN drink.

once you follow this 7 day PPI regime, and wait 15 minutes after taking the antacid, your stomach pH will be sitting at as high as ~6.5, and if you're lucky, it could be ~7, which would literally mean your stomach acid is completely neutral, and has no acid that could factor for nausea and extreme stomachaches.

at that point, the only other pain you will feel in your stomach is the irritation caused by sodium nitrite as a salt on your stomach lining, which is prone to happen for unnecessarily big amount of SN such as 25 grams. if you follow this PPI/antacid regime i gave you above, you could theoretically take as little as 5 GRAMS of SN, minimizing the irritation aswell while it still being lethal, and thats about as good as the SN method could get, friend.

i am not a doctor and i have to be honest, a dose as little as 5 grams could be a very risky gamble, especially since we have no way to tell exactly what our stomach pH is. a little higher dose which would be 15 grams is guaranteed to be as lethal as 25 grams would be if you didnt follow the regimen.

also, the PPI protocol itself will come with its own costs - you will start to feel exhausted, have muscle weakness, and possibly brainfog during those 7 days as long as you keep taking it.

it is now up to you to consider whether you want to do all of this (and are willing to be conscious for longer during SN) to truly prevent the pain. this is personally what i am strictly following for myself, too.

 

[Endisclose]

The recommended amount of propranolol is 400 mg. Thats 10 tablets at 40 mg each. I wonder if the additional tablets and the water needed for it may be a vomiting risk. Also if I didn't take it and if I get the tachycardia, that way I would know that the SN is indeed working. I plan to take benzos, so that should help with the passing out anyway.I was planning to leave out the propranolol, but I think am still a bit undecided about it..

 

[peewee]

thanks for thi

while the use of antacids/PPI/H2 blocker have been proven to lessen both stomach pain & nausea (even DRASTICALLY when done properly), the founder of exit international, dr. nitschke, tells us it will increase the amount of time it takes to lose consciousness, and therefore no longer advises it.

however, both of these claims do not contradict eachother can and still overlap. once we take both of them into account, we get 1 conclusion; the use of PPIs and antacids will lessen pain and nausea, but at the cost of increasing the time it takes for loss of consciousness.

generally taking just antacids is not enough. if you want to truly minimize this kind of pain - and im talking LITTLE TO NO PAIN/NAUSEA, this is what you do:

take a daily morning dose of 40mg of esomeprazole (PPI) for 7 whole days before the SN drink. the SN drink day is included, and so it should be the 7th day of the esomeprazole regime.

its important to note that for esomeprazole, as a PPI that slowly blocks the acid producing pumps in your stomach lining unlike antacids that just neutralize your stomach acid for a few hours, you need an empty stomach for it to work effectively. this means taking the daily dose preferably right after you wake up, ATLEAST 5 hours before your first meal.

administering an antacid will also increase the effectiveness, you take 1000mg of calcium carbonate (2 TUMS or 1 'super-strength' TUM) 15 minutes before the SN drink.

once you follow this 7 day PPI regime, and wait 15 minutes after taking the antacid, your stomach pH will be sitting at as high as ~6.5, and if you're lucky, it could be ~7, which would literally mean your stomach acid is completely neutral, and has no acid that could factor for nausea and extreme stomachaches.

at that point, the only other pain you will feel in your stomach is the irritation caused by sodium nitrite as a salt on your stomach lining, which is prone to happen for unnecessarily big amount of SN such as 25 grams. if you follow this PPI/antacid regime i gave you above, you could theoretically take as little as 5 GRAMS of SN, minimizing the irritation aswell while it still being lethal, and thats about as good as the SN method could get, friend.

i am not a doctor and i have to be honest, a dose as little as 5 grams could be a very risky gamble, especially since we have no way to tell exactly what our stomach pH is. a little higher dose which would be 15 grams is guaranteed to be as lethal as 25 grams would be if you didnt follow the regimen.

also, the PPI protocol itself will come with its own costs - you will start to feel exhausted, have muscle weakness, and possibly brainfog during those 7 days as long as you keep taking it.

it is now up to you to consider whether you want to do all of this (and are willing to be conscious for longer during SN) to truly prevent the pain. this is personally what i am strictly following for myself, too.

thanks for this - so doing this regime you would not take 400mg of the PPI 40 mins before the sn, as youve done the week, just take the tums? i would defo do this as if you said it will reduce chance of pain - i have xanax and also nitrazepam, which will knock me out , so im not worried about staying conscious

 

[what]

thanks for thi

thanks for this - so doing this regime you would not take 400mg of the PPI 40 mins before the sn, as youve done the week, just take the tums? i would defo do this as if you said it will reduce chance of pain - i have xanax and also nitrazepam, which will knock me out , so im not worried about staying conscious

yes, the esomeprazole (PPI) is stat dose, you dont take it all at once before the SN

also, you are not taking 400mg of esomeprazole, 40x7 is 280mg. 400mg would be the propranolol. i think you switched those two.

but speaking of propranolol, make sure that you let it sit for 40 minutes in the water after crushing it before you drink it. i dont know why this has to be done, but the PPeH tells us to do that and it seems like a lot of people miss that little detail