• New TOR Mirror: suicidffbey666ur5gspccbcw2zc7yoat34wbybqa3boei6bysflbvqd.onion

  • Hey Guest,

    If you want to donate, we have a thread with updated donation options here at this link: About Donations

S

Sailfisher

F’ing A
Apr 19, 2019
282
Is there any particular antidepressant you recommend with the least side effects? I know we all react to things differently, but certainly there are some that are better than others for most.
 
inconsequential

inconsequential

Enlightened
Jun 1, 2019
1,011
Cymbalta and Prozac are the only ones that haven't given me immense side effects.
 
  • Like
Reactions: dhk96
k75

k75

L'appel du Vide
Jun 27, 2019
2,541
There is no "best" since everyone is different. But I tried Trintellix, and it had no side effects at all. Prozac and lithium were relatively side effect free, as well. But none of them completely did the job for me. I'm a very complex case. :(
 
HGL91

HGL91

Warlock
Jul 2, 2019
720
Prozac made me gain 20 lbs in a few months when I took it. That was when I was 13 years old too and had a better metabolism than my now going on 28 year old self. I remember I woke up daily at 6am and dieted all through summer break to get that weight off!

For me, 20mg of Lexapro has been the best for the past 5 years.
 
  • Like
Reactions: AngelGirl
mathieu

mathieu

Enlightened
Jun 5, 2019
1,091
There's no best one. For each person there is a most effective antidepressant with the least side-effects but it could be one of many. I've never had much luck with any. Most recently on Parnate.
 
Kyrok

Kyrok

Paragon
Nov 6, 2018
970
What side effects do you most want to avoid?
 
A

a_strange_day

Arcanist
Jul 16, 2019
461
Fluoxetine (prozac) and Sertraline (zoloft) no side effects at all for me after the 2-3 initial weeks. I've tried Mirtazapine too but it knocked me down so hard that I threw it away after a week and get back to the "soft" ones.
 
  • Like
Reactions: AtomicNewt
P

Painted Bird

...///...
Jul 15, 2019
125
Many years ago when I was still naive enough to try to "cure" depression I tried many antidepressants, almost all mentioned above. None of them really worked, some temporary placebo effect at the best. Definitely a treatment-resistant depression in my case and no wonder, as I don't even consider it as an "illness" anymore, it's a part of me and goes well with my worldview.
 
Alpha_Draco_Pegasus

Alpha_Draco_Pegasus

Member
Jun 16, 2019
48
Zoloft and Lexapro caused delayed ejaculation for me (when it takes much more time and effort to reach orgasm). I was totally not cool with that side effect. Now I take Viibryd which has been on the market since 2011 and there are no sexual dysfunction side effects. I can ejaculate with ease. So happy about that. Otherwise, Zoloft, Lexapro, Paxil, etc were all great mood lifers, as long as I took a mood stabilizer such as Lithium to dampen the "(hypo)manic effects" I had experienced due to what is now considered Bi-Polar type II disorder.

I was diagnosed with this due to reacting "manically" to Paxil which is the first SSRI I took. It was mad awesome though, I felt like I could just talk on and on and on about anything uninhibitedly. So much was exciting and I took more delight in humor. I was charged up. But then I emailed my psychologist and told him off which he noticed was very unusual of me and so I was basically diagnosed just because of that email. I don't totally refute it. I guess he was right.

But that was when I was 17. In my early twenties I took Zoloft and Lexapro alone with no mood stabilizer for brief periods and I still experienced some racing thoughts and immense energy, but I was more able to control myself interactively so I didn't act like a maniac.

Others: Anafranil, an older tricyclic med, gave me awful nausea. It's like I was seconds away from throwing up 24/7, without actually throwing up. Torture.

I tried Mirtazapine as well but noticed no effects.

Along with Viibryd I take 5-HTP and L-Tyrosine because I didn't think the Viibryd was really strong enough. Maybe it isn't as powerful as the powerhouse SSRIs like Paxil, Prozac or Zoloft, but the lack of sexual side effects for me makes it worthwhile.

Natural supplements are always better unless you need that something extra from an Rx. Green Tea Extract and Saffron are some others that help me.
 
Last edited:
  • Like
Reactions: LivedTooLong
azucaramargo

azucaramargo

Enlightened
Sep 16, 2018
1,010
T
There is no "best" since everyone is different. But I tried Trintellix, and it had no side effects at all. Prozac and lithium were relatively side effect free, as well. But none of them completely did the job for me. I'm a very complex case. :(
You didn't gain weight on Lithium?
Many years ago when I was still naive enough to try to "cure" depression I tried many antidepressants, almost all mentioned above. None of them really worked, some temporary placebo effect at the best. Definitely a treatment-resistant depression in my case and no wonder, as I don't even consider it as an "illness" anymore, it's a part of me and goes well with my worldview.
Have you never considered ECT? For treatment-resistant depression? Just curious...
I've been curious about this one! Would love to hear more about your experience on this drug, if you were so inclined. I've never "met" anyone who has taken this.
 
Last edited:
  • Like
Reactions: Painted Bird
J

justanotherday

Specialist
Jul 22, 2019
397
They all had side effects for me that were horrible.
 
  • Like
Reactions: Jon86
Kirkscoobz

Kirkscoobz

Experienced
Feb 8, 2019
219
Codeine with wine and a cigarette.
Effects are quick to notice but don't last long.
 
  • Like
Reactions: AtomicNewt
k3v3r

k3v3r

Member
Apr 25, 2019
97
fluoxetine helped me in the past, although i got these very scary side effects where i would hear my name getting whispered when noone was there, feeling like i was being followed, and feeling like there were worms in my arteries and ears
 
P

Painted Bird

...///...
Jul 15, 2019
125
Have you never considered ECT? For treatment-resistant depression? Just curious...

No, I haven't considered ECT and I was never offered that, I don't know if they still do that here. It also has a very bad reputation because how it was abused in the past. Only lobotomy was worse, but fortunately it's banned now.
 
Conflicted Cat

Conflicted Cat

Experienced
May 23, 2019
256
although i got these very scary side effects where i would hear my name getting whispered when noone was there
Oh my god, I thought I was the only one! They made me take Fluoxetine years ago, and when I would try go to sleep, all I'd hear is voices calling my name over and over again. Not whispers though.
 
  • Like
Reactions: k3v3r
J

justanotherday

Specialist
Jul 22, 2019
397
I have tried most of the antidepressants over the years and either got little if any relief( that was short lived), or couldn't tolerate the medication at all because of horrible side effects. I am at wits end because I desperately need some kind of med to at least take some of the edge off of my depression and crippling anxiety.
If only I had the nerve to just try and leave this crazy world.
 
  • Hugs
Reactions: LivedTooLong

Similar threads

StillBreathing
Replies
9
Views
165
Recovery
StillBreathing
StillBreathing
Dusk till dawn
Replies
6
Views
121
Suicide Discussion
EyesOfNight
EyesOfNight
PreCambrianBliss
Replies
10
Views
171
Suicide Discussion
Praestat_Mori
P
L
Replies
4
Views
193
Recovery
Linda
Linda
Darkover
Replies
2
Views
69
Suicide Discussion
Pluto
Pluto