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LetMeGoPlease

Student
Dec 5, 2020
122
These are the antiemetics Stan's guide for SN suggests:

Droperidol- 0,25 nM. Benperidol- 0,027 nM. Trifuperidol- 0,4 nM. Spiperone- 0,053 nM. Haloperidol- 2,0. Bromperidol- 2,1. Lurasidone- 1,0 nM. Sestindole- 2,7 nM. Paliperidone- 2,8 nM. Risperidone- 4,9 nM. Olanzapine- 21 nM. Clozapine- 144 nM. Quetiapine- 245 nM

Pardon me, but I don't understand these symbols and what units they imply. Can someone please explain, is nM the same as mg?

I will talk to my psychiatrist tomorrow after a long time and hopefully I can get some antipsychotics. She will be very pleased to know that after refusing to treat myself with pharmaceuticals I am finally willing to be her little bitch. But I really need to know what I have to get from her.
 
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Cuppatea856

Member
May 27, 2020
61
I don't understand what it means "nM" means either. I looked it up on line but couldn't find info.
 
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endpages

Member
Jan 17, 2025
16

I hope it's ok to post in such an old thread, but I'm still confused about these units. I've tried online conversions for a couple of these substances to figure out how many grams I would need from nanomolars, but I always get 0.000.

I do wonder if he meant grams instead of nanomolars because I know a bit about Haloperidol and Quetiapine doses, and 2g of Haloperidol and 245g of Quetiapine would generally make sense if you were going for a dopamine-blocking antiemetic effect similar to Metoclopramide.

Another thing to consider is how quickly each drug starts to work. Metoclopramide is relatively quick (30-60min) but Haloperidol can take 2-6 hours to reach it's peak effect. And if you've been taking any of those medications for a long time, you'd probably need a higher dose.

Does anyone have any thoughts about this?