If painkiller ODs won't work, how have people died from them?

[Walilamdzi]

Max daily dosage has been reduced from 4g per day to 3g due to potential hepatotoxicity. A therapeutic index this low in an otc would NEVER be approved today.

As in it doesn't provide pain relief?

 

[MissKatrina]

There seems to some conflating of the term "painkiller," and its being used to refer to Tylenol, nsaids, and opiates, all of which have different mechanisms of action and potential dangerous effects (hepatic failure, renal failure, respiratory depression).

minor point - Tylenol would never be approved today if it were a new drug.

Pharmacist?

 

[Walilamdzi]

Pharmacist?

Huh?

 

[SleeplessSoul]

I do have quite a few? I have 37g.

View attachment 34529

Paracetamol?

 

[Walilamdzi]

Paracetamol?

500mg yeah.

 

[SleeplessSoul]

500mg yeah.

Most likely no. You'll just be very sick. How much do you weigh?

 

[Walilamdzi]

Most likely no. You'll just be very sick. How much do you weigh?

12 stone I think

 

[SleeplessSoul]

12 stone I think

I was about 11 stone when I took 64 (32g) and my paracetamol level was high but not fatal.

It's very likely it won't work. You'll definitely be sick but I don't think it's worth the risk of surviving and getting liver damage. I know this is really unhelpful but paracetamol overdoses are gross and more damaging than fatal.

 

[Walilamdzi]

I was about 11 stone when I took 64 (32g) and my paracetamol level was high but not fatal.

It's very likely it won't work. You'll definitely be sick but I don't think it's worth the risk of surviving and getting liver damage. I know this is really unhelpful but paracetamol overdoses are gross and more damaging than fatal.

Thanks for sharing your experience, even if it wasn't what I want to hear, I'd rather be realistic.

 

[SleeplessSoul]

Thanks for sharing your experience, even if it wasn't what I want to hear, I'd rather be realistic.

I'm glad. At first it was calming and then I got panicky and started throwing up. I almost damaged my liver and had to take potassium. I hope things either get better or you find a safer way (safer sounds a bit silly)

 

[Aap]

In the event anything I've posted had been misconstrued, trying to ctb with paracetamol is a very bad idea and will likely only to serve to significantly worse one's condition. No one wants to suffer for weeks or months with progressing liver failure