Depends on people but Lexapro is probably not a good idea to try to ctb. Takes a LOT of it, and even then your body's probably going to throw it up before it can reach lethal dose. Possibly brain/heart problem after. You'll be very uncomfortable for sure. Tremor, heart racing, sweating, feeling like you can't be still, possibly seizure. Talked to a patient who told me about how they experienced serotonin syndrome (we were on the topic of how it's kind of a unicorn in medical world) and they don't ever want to touch antidepressants again after that because of how horrible it was.