Resource For those ingesting pills and drugs that survive gastric acid like SN: the best way to absorb a drug as fast as possible.

[pharmacoepia]

Washington post article about study (The research paper is too technical so this article just dilutes it down. My summarize keeps the most important points and doesn't go into the classic verbosity of journalists.)

For those considering digesting pills or SN orally, apparently according to a study that used MRI scans of human bodies and a computational simulation of how pills go through gastric acid and the the duodenum into the intestine, the fastest way for an orally taken drug to enter your system is by... leaning to the right?

No, this isn't a joke. Based on this study, leaning to the right can speed up absorption rates to 10 minutes for the drug to start being metabolized. The least effective way was to lean to the left, which slowed it down to a complete crawl with a pain-staking 100 minutes for the pill to be metabolized. Sitting upright had 20 minutes of absorption.

While this study was aimed for the best position to put bed-ridden people in, I can see it being used in the future if pills become a way for euthanasia to be administered, especially for those looking for a fast CTB, legal with assistance by a physician or not. SN survives the acids of the stomach, so I can see this also being a fast way for people who are in a time-crunch and might be found in the next 30-60 minutes after the CTB attempt starts.

What do y'all think?

 

[Alcoholic Teletubby]

 

[LifeQuitter]

No, this isn't a joke. Based on this study, leaning to the right can speed up absorption rates to 10 minutes for the drug to start being metabolized. The least effective way was to lean to the left, which slowed it down to a complete crawl with a pain-staking 100 minutes for the pill to be metabolized. Sitting upright had 20 minutes of absorption.

This might explain why some goodbye threads or witness reports the person was still conscious 30 minutes later, compared to the PPH says time to pass out is around 12 minutes.

 

[Traveller12724]

This might explain why some goodbye threads or witness reports the person was still conscious 30 minutes later, compared to the PPH says time to pass out is around 12 minutes.

The PPH predicts that timeline when someone uses potentiated sn, meaning tagamet is taken with a combination of two strong AEs (meto and Ondansetron) and propranolol added to the sn mixture provided someone fasted long enough as well. Obviously potentiating is not a must but it does speed up the time according to PPEH 2022