I have recurrent and severe treatment resistant depression, with each episode lasting longer than the previous. I've tried tons of medications to no avail, but spontaneously remitted from my last episode after three years. My current one has gone on for nine months. I hope the fact that I came out of my last episode without medication means I can again. Of course, I don't know if that's the case or how long it would take. I fear that this one may not let up before I'm no longer able to take it and CTB.