Very Allergic to Meto: What are the alternatives?

[TheRealEndgame]

Last night I intended to CTB. I had meto, cimetidine, SN, and diclazepam and it should've been a peaceful exit. About 20 min before I was going to take SN and diclazepam I started having serious interactions with meto where I couldn't stop pacing and felt absolutely horrible. That horrible state prevented me from being able to CTB as I was suffering a lot and it got me really scared. The irony is had I not been allergic and my plan had worked, it probably would've been much more pleasant to die than to go through the meto allergic symptoms. Ended up pacing and screaming for about 3 hrs, could only start feeling better because I found out I could use diphenhydramine to lessen the symptoms (ended up taking 5 which was nearly a recreational dose...2 wasn't enough).

So my question is:
What other antiemetics could I possibly use and would I probably have similar interactions with them or should they be fine? Has anyone had similar experiences with meto?

 

[Barelyhuman]

How much meto did you take? I am so afraid of this happening to me. You can take Domperidone instead. It's weaker than meto but should also work. It supposedly has far fewer side effects

 

[TheRealEndgame]

How much meto did you take? I am so afraid of this happening to me. You can take Domperidone instead. It's weaker than meto but should also work

I did stat dose of 30mg 45 min before symptoms, plus 10mg about 8 hrs earlier. I think if you allergy test with less you should be fine, apparently meto is supposed to have sedating effects for most people, but it had opposite effect on me.

 

[Barelyhuman]

Did you have a reaction to the 10mg dose? I'll be trying it out today or tomorrow. Fortunately I have Benadryl on hand and Domperidone as well in case I have a bad reaction

 

[TheRealEndgame]

Did you have a reaction to the 10mg dose?

Probably a bit of one, I saw the signs but ignored them.

 

[Barelyhuman]

Sorry you had to go through that. It sounds terrible

 

[angie]

Did you have a reaction to the 10mg dose? I'll be trying it out today or tomorrow. Fortunately I have Benadryl on hand and Domperidone as well in case I have a bad reaction

Hi does cetrizine hydrochloride help if you have a reaction to cirulan meto its a brand of reglan ? do you know ? if you have a reaction to meto how much benadryl would you have to take to help the reaction . i have cetrizine but not sure how much i would have to take if i have adverse effect from the meto . thanks

 

[TheRealEndgame]

Hi does cetrizine hydrochloride help if you have a reaction to cirulan meto its a brand of reglan ? do you know ? if you have a reaction to meto how much benadryl would you have to take to help the reaction . i have cetrizine but not sure how much i would have to take if i have adverse effect from the meto . thanks

I don't know about Zyrtec but Benadryl definitely helped me with the adverse symptoms. I started with 50mg of Benadryl but it wasn't really enough, it helped some but I was still wanting to pace and couldn't sit still. Ended up taking 125mg of Benadryl, which did the trick but was probably more than I should've taken. It stopped about 75% of the meto allergy symptoms, but I looked in the mirror and had dilated pupils. Probably start with 50mg and wait a bit before taking more if it happens to you.

 

[eve2004]

Ouch that's terrible... ! Has anyone tried prochlorperazine?

I guess allergy testing of antiemetics should be added to the protocol... I'd test the ranitidine/cim as well. I personally would also want to test the SN just to be sure it will do *something* and if it does nothing, I'll know I'll need a high dose. Not sure the safe amount but either way irs a win-win whagever happens right?