Reglan (metoclopramide) side effects sound scary :\

[CiproKilledMe]

The PPH recommends metoclopramide as the anti-emitic of choice with N, but the potential side effects sound really scary! It has a black box warning for tardive dyskinesia and can supposedly make your anxiety WAY worse (which would NOT be helpful whilst trying to ctb). I'm actually more scared of the metoclopramide than I am of the N. PPH recommends testing the metoclopramide ahead of time to make sure you can handle it, but what if you can't? The last thing I want is to cause myself more problems than I already have. I do not want to die in the throws of a panic attack. And why would anyone risk developing permanent tardive dyskinesia just to avoid being nauseous?? Man, Rx drugs are fucked.

Anyway, are there any safer options? Or do I just risk it without an anti-emitic? I don't have a good track record with drug side effects. They always seem to happen to me.

 

[Seiba]

The PPH recommends metoclopramide as the anti-emitic of choice with N, but the potential side effects sound really scary! It has a black box warning for tardive dyskinesia and can supposedly make your anxiety WAY worse (which would NOT be helpful whilst trying to ctb). I'm actually more scared of the metoclopramide than I am of the N. PPH recommends testing the metoclopramide ahead of time to make sure you can handle it, but what if you can't? The last thing I want is to cause myself more problems than I already have. I do not want to die in the throws of a panic attack. And why would anyone risk developing permanent tardive dyskinesia just to avoid being nauseous?? Man, Rx drugs are fucked.

Anyway, are there any safer options? Or do I just risk it without an anti-emitic? I don't have a good track record with drug side effects. They always seem to happen to me.

A lot of medications have side effect warnings. I'm not trying to invalidate your emotions, but does one panic attack sound worse than never knowing if you have a secure method? In all likely hood you will have a safe reaction, and testing it is the only way to know how your body would react. If you are afraid of a panic attack do not even bother trying SN without antiemetics, re-read the method threads on SN already published and understand that going in without a regimen or a stat dose is a sure bound way to fail as you can find if you search for SN "failures" which are people who did not prepare with the antiemetics and did not prepare a second drink beforehand in case they threw up. If you do have have a reaction, then you can look into other antiemetics options as you can find mentioned in the SN method threads. The only method most likely safer than SN would be shotgun or N the latter of which you would still need antiemetics.

 

[ben7]

I feel the same, I worry about an anti-emetic as i have some damage from previous antidepressant use and could react badly to it. I've definitely considered the idea of N without an ant-emetic as it's one less thing to react badly to. I've heard cases of people doing this, but it doesn't get discussed much. The other option is to use a milder anti-emetic than Meto I guess which are available.

 

[hermes]

Do any of you know of anybody who had bad side effects of Meto? I mean side effects which make it unusable in CTB regimen?

 

[ben7]

I think there are some examples, just like some people have a bad reaction to antidepressants or other drugs. I think if you're fit and healthy it's less likely but I'm really not qualified to say. I'd like to get some more clarity on not taking an anti-emetic with N - some people on here seem to think its fine, others not.

 

[Thegoldenapples]

Do any of you know of anybody who had bad side effects of Meto? I mean side effects which make it unusable in CTB regimen?

Yeah there's been a few people on here but that's why there are substitutes in the PPH. No one on here had long term effects, just for the day. I tested 10mg and stomach was sore but bearable. Passed after about 4 hours. Couldn't take 30mg at once though so opted for the 48 hour regime. I'm super sick though and stomach is quite sensitive. A recommended to take 2x 20mg 8 hours apart the day of, with the last dose an hour prior to N. Meto is considered to be best, that's why it's recommended.

I think there are some examples, just like some people have a bad reaction to antidepressants or other drugs. I think if you're fit and healthy it's less likely but I'm really not qualified to say. I'd like to get some more clarity on not taking an anti-emetic with N - some people on here seem to think its fine, others not.

Personally, I wouldn't risk taking N without a AE. Throwing that shit up and failing would be a nightmare.

 

[ben7]

Yeah there's been a few people on here but that's why there are substitutes in the PPH. No one on here had long term effects, just for the day. I tested 10mg and stomach was sore but bearable. Passed after about 4 hours. Couldn't take 30mg at once though so opted for the 48 hour regime. I'm super sick though and stomach is quite sensitive. A recommended to take 2x 20mg 8 hours apart the day of, with the last dose an hour prior to N. Meto is considered to be best, that's why it's recommended.

Personally, I wouldn't risk taking N without a AE. Throwing that shit up and failing would be a nightmare.

Thanks - maybe I will test out a milder AE and if I don't react, from what your saying, the 48 hour regime might be best for those who are sensitive.

 

[CiproKilledMe]

A lot of medications have side effect warnings. I'm not trying to invalidate your emotions, but does one panic attack sound worse than never knowing if you have a secure method? In all likely hood you will have a safe reaction, and testing it is the only way to know how your body would react. If you are afraid of a panic attack do not even bother trying SN without antiemetics, re-read the method threads on SN already published and understand that going in without a regimen or a stat dose is a sure bound way to fail as you can find if you search for SN "failures" which are people who did not prepare with the antiemetics and did not prepare a second drink beforehand in case they threw up. If you do have have a reaction, then you can look into other antiemetics options as you can find mentioned in the SN method threads. The only method most likely safer than SN would be shotgun or N the latter of which you would still need antiemetics.

I'm looking to use N as opposed to SN. I just read so many horrifying accounts of meto from here: https://www.askapatient.com/viewrating.asp?drug=17854&name=REGLAN

In addition, I also have to worry about my meto even being legit in the first place as I bought it from an overseas online pharmacy. Who knows--they may have just sent me flour pills!

The entire reason I'm being forced to ctb in the first place is because I had a horrific and permanently-disabling adverse reaction to a Rx medication (Cipro). That experience has made me SO much more cautious of prescription drugs, especially ones with black box warnings! I wish I'd read up on meto's side effects more in-depth prior to ordering it but I never fathomed a simple anti-nausea medication would come with such potentially serious side effects! Now I'm left here wanting to ctb but too scared to because of the stupid anti-emitic! Is there any safer alternative anti-emitic I could order off of Amazon? I can't wait another 3-4 weeks to buy something from overseas.

 

[ben7]

I'm looking to use N as opposed to SN. I just read so many horrifying accounts of meto from here: https://www.askapatient.com/viewrating.asp?drug=17854&name=REGLAN

In addition, I also have to worry about my meto even being legit in the first place as I bought it from an overseas online pharmacy. Who knows--they may have just sent me flour pills!

The entire reason I'm being forced to ctb in the first place is because I had a horrific and permanently-disabling adverse reaction to a Rx medication (Cipro). That experience has made me SO much more cautious of prescription drugs, especially ones with black box warnings! I wish I'd read up on meto's side effects more in-depth prior to ordering it but I never fathomed a simple anti-nausea medication would come with such potentially serious side effects! Now I'm left here wanting to ctb but too scared to because of the stupid anti-emitic! Is there any safer alternative anti-emitic I could order off of Amazon? I can't wait another 3-4 weeks to buy something from overseas.

I know what you mean, I am in the same position because of a previous adverse reaction and it makes you really nervous about any prescription drugs. I know for some it seems laughable to be more nervous about the AE than N but I think unless you've been damaged previously it's hard to understand. For me it comes down to either no AE with N, or a milder AE. There are definitely milder AE options than Meto listed in the PPH which is good (although I'm still a bit nervous about them, but I may just have to test and take it from there).

 

[quiet.rabbit]

I'm looking to use N as opposed to SN. I just read so many horrifying accounts of meto from here: https://www.askapatient.com/viewrating.asp?drug=17854&name=REGLAN

In addition, I also have to worry about my meto even being legit in the first place as I bought it from an overseas online pharmacy. Who knows--they may have just sent me flour pills!

The entire reason I'm being forced to ctb in the first place is because I had a horrific and permanently-disabling adverse reaction to a Rx medication (Cipro). That experience has made me SO much more cautious of prescription drugs, especially ones with black box warnings! I wish I'd read up on meto's side effects more in-depth prior to ordering it but I never fathomed a simple anti-nausea medication would come with such potentially serious side effects! Now I'm left here wanting to ctb but too scared to because of the stupid anti-emitic! Is there any safer alternative anti-emitic I could order off of Amazon? I can't wait another 3-4 weeks to buy something from overseas.

Dramanine with Meclizine as an active ingredient is a good OTC alternative in Amazon according to the PPeH. Just make sure you buy the one with meclizine, its the one thats non-drowsy formula I believe. Its a dopamine blocker like meto.

 

[ben7]

Dramanine with Meclizine as an active ingredient is a good OTC alternative in Amazon according to the PPeH. Just make sure you buy the one with meclizine, its the one thats non-drowsy formula I believe. Its a dopamine blocker like meto.

Domperidone also meant to me milder so looks like my best option

 

[CiproKilledMe]

Dramanine with Meclizine as an active ingredient is a good OTC alternative in Amazon according to the PPeH. Just make sure you buy the one with meclizine, its the one thats non-drowsy formula I believe. Its a dopamine blocker like meto.

Thank you! That's what I'll order then. Dramanine's 5-star Amazon rating gives me a lot more confidence than metoclopramide's 1.4-star rating from people on askapatient.com! Dramanine might not be the best choice for N, but I'm assuming it's still better than nothing! This relieves a lot of my anxiety, thank you again.

Dramanine with Meclizine as an active ingredient is a good OTC alternative in Amazon according to the PPeH. Just make sure you buy the one with meclizine, its the one thats non-drowsy formula I believe. Its a dopamine blocker like meto.

Sorry, just one more question: In my 2021 version of the PPH it shows a picture of the 'Original Formula' Dramamine and doesn't mention anything about Meclizine. Did they change their recommendation at some point? I want to make sure I order the right version. Thanks!

 

[ben7]

Dramanine with Meclizine as an active ingredient is a good OTC alternative in Amazon according to the PPeH. Just make sure you buy the one with meclizine, its the one thats non-drowsy formula I believe. Its a dopamine blocker like meto.

Does anyone know where to get Dramamine with Meclizine from?

 

[loopylou]

I didn't feel a thing from taking it . Maybe take 3 to remove your fear?

 

[quiet.rabbit]

Thank you! That's what I'll order then. Dramanine's 5-star Amazon rating gives me a lot more confidence than metoclopramide's 1.4-star rating from people on askapatient.com! Dramanine might not be the best choice for N, but I'm assuming it's still better than nothing! This relieves a lot of my anxiety, thank you again.



Sorry, just one more question: In my 2021 version of the PPH it shows a picture of the 'Original Formula' Dramamine and doesn't mention anything about Meclizine. Did they change their recommendation at some point? I want to make sure I order the right version. Thanks!

They didn't mention it in the PPeH, but the drug used in the original formula is not good as it does not block dopamine receptors which is what it needs to do to reduce nausea. Only the one with meclizine does. I do not know why they show that picture, but you can confirm this yourself. I think meto is still better though as it also speeds up SN absorption unlike meclizine.

Does anyone know where to get Dramamine with Meclizine from?

Like I said in the post, you can find it on Amazon as Dramanine Non-Drowsy Formula if you're in the US. I don't know about other countries.

 

[ben7]

They didn't mention it in the PPeH, but the drug used in the original formula is not good as it does not block dopamine receptors which is what it needs to do to reduce nausea. Only the one with meclizine does. I do not know why they show that picture, but you can confirm this yourself. I think meto is still better though as it also speeds up SN absorption unlike meclizine.

Like I said in the post, you can find it on Amazon as Dramanine Non-Drowsy Formula if you're in the US. I don't know about other countries.

Thanks it looks like Dramamine-N Long Lasting is the one with Meclizine, looks like the Non-Drowsy Formula is the 'natrual' one with ginger, etc so probably wouldn't work. It's difficult to get worldwide but not impossible.

Thanks it looks like Dramamine-N Long Lasting is the one with Meclizine, looks like the Non-Drowsy Formula is the 'natrual' one with ginger, etc so probably wouldn't work. It's difficult to get worldwide but not impossible.

Oh the 'All Day Less Drowsy' variety has Meclizine too

 

[CiproKilledMe]

They didn't mention it in the PPeH, but the drug used in the original formula is not good as it does not block dopamine receptors which is what it needs to do to reduce nausea. Only the one with meclizine does. I do not know why they show that picture, but you can confirm this yourself. I think meto is still better though as it also speeds up SN absorption unlike meclizine.

So if I take N with Dramamine it'll just take longer to ctb than if I took N with meto? Wouldn't I be unconscious either way? Thanks for your help!

 

[Seiba]

I'm looking to use N as opposed to SN. I just read so many horrifying accounts of meto from here: https://www.askapatient.com/viewrating.asp?drug=17854&name=REGLAN

In addition, I also have to worry about my meto even being legit in the first place as I bought it from an overseas online pharmacy. Who knows--they may have just sent me flour pills!

The entire reason I'm being forced to ctb in the first place is because I had a horrific and permanently-disabling adverse reaction to a Rx medication (Cipro). That experience has made me SO much more cautious of prescription drugs, especially ones with black box warnings! I wish I'd read up on meto's side effects more in-depth prior to ordering it but I never fathomed a simple anti-nausea medication would come with such potentially serious side effects! Now I'm left here wanting to ctb but too scared to because of the stupid anti-emitic! Is there any safer alternative anti-emitic I could order off of Amazon? I can't wait another 3-4 weeks to buy something from overseas.

Sorry about SN, it was really late last night at three am and I hadn't slept. The latter I wrote about N stuff applies. No there's nothing going to be sold on amazon for you to take let alone a safer alternative on amazon alone. What you can get on amazon are acid reducers which are helpful in combo with antiemetics. SN threads still go over choice of antiemetic, there's a few other options mentioned in those threads. Antipsychotics, and a few other just antiemetic options like domperidone. Keep in mind review sites are also skewered to negative experiences because no one happy with their medication will use a review site. In the united states alone there's been over two million prescriptions for meto, yet the review site you linked had six hundred reviews. If meto still remains something you are worried about due to past experiences of meds, perhaps looking into the other options mentioned in the threads. Maybe what the other user mentioned with meclizine? It's been a while since I've been in those threads or the PPH and it seems you checked the PPH yourself. I'm not sure going over the counter would the best way if you desire to reduce side effects, being over the counter doesn't really mean no possible side effects either.

Source https://clincalc.com/DrugStats/Drugs/MetoclopramideHydrochloride

 

[CiproKilledMe]

Sorry about SN, it was really late last night at three am and I hadn't slept. The latter I wrote about N stuff applies. No there's nothing going to be sold on amazon for you to take let alone a safer alternative on amazon alone. What you can get on amazon are acid reducers which are helpful in combo with antiemetics. SN threads still go over choice of antiemetic, there's a few other options mentioned in those threads. Antipsychotics, and a few other just antiemetic options like domperidone. Keep in mind review sites are also skewered to negative experiences because no one happy with their medication will use a review site. In the united states alone there's been over two million prescriptions for meto, yet the review site you linked had six hundred reviews. If meto still remains something you are worried about due to past experiences of meds, perhaps looking into the other options mentioned in the threads. Maybe what the other user mentioned with meclizine? It's been a while since I've been in those threads or the PPH and it seems you checked the PPH yourself. I'm not sure going over the counter would the best way if you desire to reduce side effects, being over the counter doesn't really mean no possible side effects either.

Source https://clincalc.com/DrugStats/Drugs/MetoclopramideHydrochloride

Thanks. I was just hoping to order something OTC because I'd get it quicker. I'm kind of out of time here. I ordered some Dramamine w/ meclizine...hopefully that's better than nothing with N.

 

[Seiba]

Thanks. I was just hoping to order something OTC because I'd get it quicker. I'm kind of out of time here. I ordered some Dramamine w/ meclizine...hopefully that's better than nothing with N.

Best of luck, sorry had again for writing about SN at three even if the antiemetic logic is the same in the end.

 

[ben7]

Sorry about SN, it was really late last night at three am and I hadn't slept. The latter I wrote about N stuff applies. No there's nothing going to be sold on amazon for you to take let alone a safer alternative on amazon alone. What you can get on amazon are acid reducers which are helpful in combo with antiemetics. SN threads still go over choice of antiemetic, there's a few other options mentioned in those threads. Antipsychotics, and a few other just antiemetic options like domperidone. Keep in mind review sites are also skewered to negative experiences because no one happy with their medication will use a review site. In the united states alone there's been over two million prescriptions for meto, yet the review site you linked had six hundred reviews. If meto still remains something you are worried about due to past experiences of meds, perhaps looking into the other options mentioned in the threads. Maybe what the other user mentioned with meclizine? It's been a while since I've been in those threads or the PPH and it seems you checked the PPH yourself. I'm not sure going over the counter would the best way if you desire to reduce side effects, being over the counter doesn't really mean no possible side effects either.

Source https://clincalc.com/DrugStats/Drugs/MetoclopramideHydrochloride

This is so helpful thanks - I hope you don't mind me asking you a question on this thread - I too am looking to avoid Meto as a result of previous Rx damage and am trying to establish whether Domperidone is safer or Dramamine is safer still? I was thinking of avoiding an antiemetic with N full stop, but that seems like a bad idea so need to chose one.

 

[Seiba]

This is so helpful thanks - I hope you don't mind me asking you a question on this thread - I too am looking to avoid Meto as a result of previous Rx damage and am trying to establish whether Domperidone is safer or Dramamine is safer still? I was thinking of avoiding an antiemetic with N full stop, but that seems like a bad idea so need to chose one.

If I had to choose between those two I would go with domperidone myself. The suggestion of dramamine with meclizine was the first time I ever remember hearing about it, but I'm not exactly researched on over the counter medicine. One of the problems with domperidone is it's no longer produced in the united states because of complications it has with cancer patients so you would need to import it. Something to keep in mind if you do stat dose and drink SN or N as long as you don't throw up you'll likely be dead, so even if some side effects happen it might be a better option than a regimen if you're worried about experiencing side effects while alive that's a compromise.

 

[ben7]

If I had to choose between those two I would go with domperidone myself. The suggestion of dramamine with meclizine was the first time I ever remember hearing about it, but I'm not exactly researched on over the counter medicine. One of the problems with domperidone is it's no longer produced in the united states because of complications it has with cancer patients so you would need to import it. Something to keep in mind if you do stat dose and drink SN or N as long as you don't throw up you'll likely be dead, so even if some side effects happen it might be a better option than a regimen if you're worried about experiencing side effects while alive that's a compromise.

thanks a lot

 

[Bauhaus]

I once tried meto and it made me really nervous.
I don't have this with olanzapine which is also a dopamine antagonist.

 

[ben7]

If I had to choose between those two I would go with domperidone myself. The suggestion of dramamine with meclizine was the first time I ever remember hearing about it, but I'm not exactly researched on over the counter medicine. One of the problems with domperidone is it's no longer produced in the united states because of complications it has with cancer patients so you would need to import it. Something to keep in mind if you do stat dose and drink SN or N as long as you don't throw up you'll likely be dead, so even if some side effects happen it might be a better option than a regimen if you're worried about experiencing side effects while alive that's a compromise.

Sorry one quick further question - do you think testing the AE in advance is wise (I'm worried a bad reaction might put me off) or just wait until the night because it sort of won't matter anyway at that stage as there's no turning back?

 

[Seiba]

Haven't been in that position myself so trusting yourself might be the wisest option. Personally my choice would be to do stat dose with two glasses of SN prepared. If you do decide to try it beforehand to see if it gives you a bad reaction I don't see a bad reaction lasting for weeks.

 

[ben7]

Haven't been in that position myself so trusting yourself might be the wisest option. Personally my choice would be to do stat dose with two glasses of SN prepared. If you do decide to try it beforehand to see if it gives you a bad reaction I don't see a bad reaction lasting for weeks.

It will be N but thank you, I will decide between Domp and Dram

 

[Seiba]

It will be N but thank you, I will decide between Domp and Dram

Yeah, I mentioned SN since it was about what I would do personally. N isn't my method so other than the antiemetics I can't really comment on if you should prepare more glasses or not.

 

[checkouttime]

There is a list of alternatives to using METO, It is advised to test any anti-e before you take it though anyway



there haven't been any reports of any drastic circumstances in regards to a person taking an anti-e and the people from EXIT international(the PPH) have experienced a very high number of people that have CTB. the side effects that can happen with stuff are mentioned because it wouldn't be good practice to not mention things that happen in VERY RARE cases. Its like the same thing for the COVID jab, we are told it can cause blood clots, but this is in VERY RARE cases and the realisation is that most people will be perfectly fine. I mean even cannabis can be used as an anti-e!! obviously many of these drugs are prescribed on a daily basis to MILLIONS of patients for certain treatments, if the side effects were a really common occurrence they would be available on prescription.

I might add, alot of members and cases have been reported of people not using an anti-e at all. I did see a post where a member even advised not testing the anti-e, the reason being the side effects mentioned DO NOT take effect until after a certain amount of time, you will be long gone before that happens. For instance there have been cases of people taking the N and passing out while drinking it!!! I'll try and find the post for you!

EDIT i found the post about METO

If one is concerned about EPS, the single dose method without testing is all that should be utilized. EPS are usually or often irreversible and can develop 24-72 hours after a single dose though more often after repeated doses. EPS are rare, though with the general level of anxiety of most users here, the advice to test meto is the worst advice that could be followed.

Its in this thread https://sanctioned-suicide.net/threads/questions-about-metoclopramide.66861/#post-1274926

the person has CLEARLY done their research, thanks god people post things that they know about, we'd be lost without them wouldn't we!!!!

 

[Anonymous 4]

I'm looking to use N as opposed to SN. I just read so many horrifying accounts of meto from here: https://www.askapatient.com/viewrating.asp?drug=17854&name=REGLAN

In addition, I also have to worry about my meto even being legit in the first place as I bought it from an overseas online pharmacy. Who knows--they may have just sent me flour pills!

The entire reason I'm being forced to ctb in the first place is because I had a horrific and permanently-disabling adverse reaction to a Rx medication (Cipro). That experience has made me SO much more cautious of prescription drugs, especially ones with black box warnings! I wish I'd read up on meto's side effects more in-depth prior to ordering it but I never fathomed a simple anti-nausea medication would come with such potentially serious side effects! Now I'm left here wanting to ctb but too scared to because of the stupid anti-emitic! Is there any safer alternative anti-emitic I could order off of Amazon? I can't wait another 3-4 weeks to buy something from overseas.

Hay would you mind sharing the site that you ordered the AE from please? You can also check the website for reliability, by that I mean you check who owns the domain, weather the IP address is being hidden or spoofed, and who the DNS server for the web page is, and from that you will know weather the site is bogus, or if it is a legit place selling what they claim to be selling