I've been unhappy since adolescence. What kept me going was my family's love, the love of a previous partner (split was amicable), and the general hope that things might get better.
Developed a facial skin condition in my late 20s which rendered me a virtual shut in. My depression and anxiety worsened, and a few years later had a nervous breakdown. Was very close to jumping in front of a train. But recovered somewhat - again, with the love and care from family. No job, no life, no future, no friends, no partner, but able to hang on. Managed to control the skin condition. Life was bearable, just. I had my music, books, movies.
In recent months, another facial skin condition has developed on top of the previous one, I've developed sudden chronic ear pain which prevents me from listening to music or watching movies. My last defences are gone.