IMO absolutely-fucking-yes. However, not alcohol, I honestly personally dislike that intoxicating feeling it provides and would rather stick to a joint or any other drug in general. I've done just about everything in the books. Now, as to which ones you should do? everyone is different so you need to find your poison. I'll try and explain what each one is good for though. For me, in terms of stimulants, I love dextroamphetamine, methamphetamine (low dose though), and caffeine for both focus and the awesome euphoric buzz. When I do any amphetamines, I do them orally via Adderall pills. I have 30 MG script footballs and some pressed ones that are mix between D-Amphetamine and M-Amphetamine. As long as you don't go crazy on the dose, I honestly can't tell the difference. A lot of people talk about amphetamines like you're bound to go schizo from using them. That's honestly bullshit. You just need to be careful and monitor yourself. You should never get to a point of taking 30 MG+ within a 48 hour period (unless you actually have ADHD or some other disorder and that's your appropriate dose). Take a few weeks every now and then to detox off every stimulant and you'll be okay. As for caffeine? I'm a sucker for those Monster Energy drinks and if not that some 200 MG Caffeine pills do the job. If I ever have a day where I just don't want to do work or I've just been really physically taxed from the previous day and could use a pick me up then those are my choices. For therapeutic purposes I love Psychedelics but I definitely prefer Acid over Psilocybin because Acid lasts longer + is more stimmy and I love that feeling. For anxiety purposes people typically recommend benzodiazepine drugs like Xanax (Alprazolam) and other drugs amongst it. However, ironically enough, I think adderall does a way better job than any benzo ever could. I've done many benzodiazepines too so I think I come with some pretty good experience (all US script benzos + RC's like bromaz, etiz, fluap, flual, etc). In my opinion, benzos are a waste of time. Just go buy some weed instead of doing benzos. Adderall not only helps with focus but with the tad bit of extra serotonin and dopamine which counteracts my anxiety so its enough to get me through the day. At the end of the day, you gotta experiment with these compounds with yourself to find what works for you.