Discussion Does Domperidone enough to the SN method? Or Metoclopramide is necessary?

[apple0613]

So, at my place, SN is easy to get. For me, the hardest part for the SN method is Antiemetic.

In a sticky thread of this forum, Metoclopramide is the only Antiemetic suggested, which needs a prescription.
But there were other complete SN guides like this one suggesting some other Antiemetic options, one of them is Domperidone.

Just very recently, I found that Domperidone is kind of easy to get, maybe I can buy it directly from local pharmacy, not like Metoclopramide, which I need a prescription.
So if Domperidone is a valid option, it'll be much easier for me to do all the preparation for the SN method.

Can someone explains this for me?
Thanks.

 

[black money boys]

it is generally agreed that dramamine is the best OTC AE for SN if you cant get meto. its on amazon

 

[InTheAbyss]

Just porting to follow if anyone else has info on this. In my country both Meto and Dom are prescription only.

For me the pharmacy got the doctor to change the prescription from Meto to Dom because of possible interactions with my other medications.

Anyone know how effective Dom is vs Meto?

 

[kamyzyak]

Just porting to follow if anyone else has info on this. In my country both Meto and Dom are prescription only.

For me the pharmacy got the doctor to change the prescription from Meto to Dom because of possible interactions with my other medications.

Anyone know how effective Dom is vs Meto?

PPH mentions Dom as one of the possible antiemetics in the SN protocol. It, like Meto, accelerates gastric emptying, which should speed up the entry of SN into the bloodstream, and has the same mechanism of action. Meto is mentioned as a more effective antiemetic, but I'm not sure how significant the difference is, because on the internet it is usually mentioned that Meto and Dom are quite similar in effectiveness. Did a quick research and in some studies Dom is cited as being more effective for nausea/vomiting forcertain conditions, while in others Meto shows itself to be better, but the difference is usually not drastic.

 

[tyrcap]

Why not take both?

 

[EmptyBottle]

Why not take both?

not sure if they impact each other negatively when combined or not, tho good question.

 

[Zardoz]

The PPH lists a few antiemetics that should be effective, including Domperidone (which I understand is not available in the US).
It'll likely be just as good as meto or any other prescription AE.
I was intending to use it, but it has interactions with some regular meds I take, so I'm going with a combination of Meto and Ondansetron (this is the recommendation for the 5-drug mix method in the PPH), at a lower dose of each compared to taking on their own.

 

[azoidant]

You can find meto on some... questionable online pharmacies if you look around. I'm in the US where it's not OTC so I ordered some online. I was under the impression it'd be mailed domestically but it was actually international, but it still got delivered without any problems.

 

[Alexandra_]

Domperidone is from the same group of dopamine receptor blockers as Metoclopramide. I have tested both drugs. Metoclopramide gave me very painful side effects. Domperidone did not. So I will use it before SN

 

[socksnsandles]

Domperidone is from the same group of dopamine receptor blockers as Metoclopramide. I have tested both drugs. Metoclopramide gave me very painful side effects. Domperidone did not. So I will use it before SN

what meto dose r u going with?

 

[Alexandra_]

what meto dose r u going with?

SN

 

[EmptyBottle]

SN

mmm, tho that is the salt... not the meto dose ^^

Maybe the dose is 2 tablets... one sometime before and one shortly before SN?

 

[Alexandra_]

mmm, tho that is the salt... not the meto dose ^^

Maybe the dose is 2 tablets... one sometime before and one shortly before SN?

I will follow the protocol - 48-hour regime

 

[socksnsandles]

SN

are you not gonna take an antiemetic with the sn?

 

[Alexandra_]

are you not gonna take an antiemetic with the sn?

I'm going to take Domperidone, I wrote about it in the comment above