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PursuitofWonder

PursuitofWonder

Student
Dec 12, 2020
137
So the DDMP2 medication cocktail is used in place of N in medical settings where it is legal. The combo is as follows:
Diazepam 1 gram
Digoxin 50mg
Morphine sulfate: 15 grams
Propranolol 2grams
Now I can get access to the DMP pretty easily, however the Digoxin would be a challenge as it's not sold anywhere online and to get a script from a doc you'd have to fake a heart condition which I'm pretty sure is impossible. My question is, is the second D absolutely necessary? I'm not sure what it's complete purpose is but I would like to know if I can go without it.
 
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A

Aap

Enlightened
Apr 26, 2020
1,856
This seems like a questionable post. Digoxin is the easiest to obtain on that list next to propranolol. The purpose of the medications is to cause a cascading series of failures that result in a rapid exit. It isn't essential, though it is the only thing in the combo (other than morphine) that can cause death alone in the amount listed.
 
PursuitofWonder

PursuitofWonder

Student
Dec 12, 2020
137
This seems like a questionable post. Digoxin is the easiest to obtain on that list next to propranolol. The purpose of the medications is to cause a cascading series of failures that result in a rapid exit. It isn't essential, though it is the only thing in the combo (other than morphine) that can cause death alone in the amount listed.
Look I didn't mean to be questionable, I legitimately couldn't find it anywhere, if that's a problem then sue me.
 
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DetachedDreamer97

DetachedDreamer97

Enlightened
Mar 17, 2018
1,402
It is. It's on inhousepharmacy. But if in doubt, cerberin from pong pong seeds would prove an effective alternative. They're found on ebay, and are cheap. One seed is sufficient to provide a lethal dose, though taking a minimum 3 would be recommended.
 
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PursuitofWonder

PursuitofWonder

Student
Dec 12, 2020
137
It is. It's on inhousepharmacy. But if in doubt, cerberin from pong pong seeds would prove an effective alternative. They're found on ebay, and are cheap. One seed is sufficient to provide a lethal dose, though taking a minimum 3 would be recommended.
Alright thanks for the info, that should work.
 
M

MAA Ke pass

Student
Jan 6, 2021
130
So the DDMP2 medication cocktail is used in place of N in medical settings where it is legal. The combo is as follows:
Diazepam 1 gram
Digoxin 50mg
Morphine sulfate: 15 grams
Propranolol 2grams
Now I can get access to the DMP pretty easily, however the Digoxin would be a challenge as it's not sold anywhere online and to get a script from a doc you'd have to fake a heart condition which I'm pretty sure is impossible. My question is, is the second D absolutely necessary? I'm not sure what it's complete purpose is but I would like to know if I can go without it.
How can I get morphine???
 
DetachedDreamer97

DetachedDreamer97

Enlightened
Mar 17, 2018
1,402
How can I get morphine???
You'll have to search on the dark web. Keep in mind, that there are alternatives to morphine such as fentanyl, heroin, codeine, oxycodone, etc... For weaker opiates, you'll need scopolamine to potentiate the sedative+analgesic qualities.

If no luck, loperamide would arguably work as an otc alternative opiate, however, you'll need a p-glycoprotein inhibitor as well as a cytochrome inhibitor in order to have it cross the blood brain barrier. It'll also have to be taken at a supra-therapeutic dose.

There is also akuamma, california poppy, and incarvillea sinensis (granted, the combination probably won't be useful for respiratory depression, it'll just ease pain and perhaps diarrheal symptoms of digoxin).
For loperamide and the herbal combination, scopolamine is necessary for potentiation.
 
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N

Nigh

Experienced
Oct 12, 2020
223
It is. It's on inhousepharmacy. But if in doubt, cerberin from pong pong seeds would prove an effective alternative. They're found on ebay, and are cheap. One seed is sufficient to provide a lethal dose, though taking a minimum 3 would be recommended.
Is there a particular type of pong pong seeds you need?
 
DetachedDreamer97

DetachedDreamer97

Enlightened
Mar 17, 2018
1,402
Is there a particular type of pong pong seeds you need?
Not really, it can either be cerbera odollam or manghas.

What I will say though is that for better results, it's better consumed as a tincture vs raw seeds. Considering raw plant material is rich in cellulose and indigestible fiber that impedes absorption of cerberin. This is what causes variability in time before death upon ingestion of seeds.
 
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N

Nigh

Experienced
Oct 12, 2020
223
Not really, it can either be cerbera odollam or manghas.

What I will say though is that for better results, it's better consumed as a tincture vs raw seeds. Considering raw plant material is rich in cellulose and indigestible fiber that impedes absorption of cerberin. This is what causes variability in time before death upon ingestion of seeds.
Is it true that ingesting poppy seeds is painful?
 
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DetachedDreamer97

DetachedDreamer97

Enlightened
Mar 17, 2018
1,402
Sorry,* pong pong seeds. Lol
Oh, then yeah; by default it is very unpleasant by itself. Just like the cardenolide digoxin, it causes vomiting, diarrhea, colicky abdominal pain upon ingestion, as well other symptoms. Hence, it's best to be taken as a cocktail.
 
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DetachedDreamer97

DetachedDreamer97

Enlightened
Mar 17, 2018
1,402
Do you know why the effects are different when taken with other drugs?
Why yes... Each of the three drugs like morphine, diazepam, and propranol has a place in easing symptoms and potentiating the effects of the digoxin-type cardenolide. Though morphine is also a deadly agent as it produces respiratory depression, especially when it's combined with diazepam, I believe morphine also plays its role in not only easing pain, but also treating diarrhea and colic spasms caused by digoxin and metoclopramide (assuming you're using that as your choice of antiemetic). With the slowed gastric motility, it allows for more of the poison to be absorbed.

Propranolol is used for potentiating the bradycardic effects of digoxin, and prevents hypertension and possible initial tachycardia.

Diazepam is used for anxiety and to induce sleep, so you won't have to be conscious.
 
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N

Nigh

Experienced
Oct 12, 2020
223
Why yes... Each of the three drugs like morphine, diazepam, and propranol has a place in easing symptoms and potentiating the effects of the digoxin-type cardenolide. Though morphine is also a deadly agent as it produces respiratory depression, especially when it's combined with diazepam, I believe morphine also plays its role in not only easing pain, but also treating diarrhea and colic spasms caused by digoxin and metoclopramide (assuming you're using that as your choice of antiemetic). With the slowed gastric motility, it allows for more of the poison to be absorbed.

Propranolol is used for potentiating the bradycardic effects of digoxin, and prevents hypertension and possible initial tachycardia.

Diazepam is used for anxiety and to induce sleep, so you won't have to be conscious.
Thank you. Just wondered if codeine, although far weaker than morphine, could be an alternative to stopping spasms and diarrhea, as morphine is not so easy to obtain.
 
DetachedDreamer97

DetachedDreamer97

Enlightened
Mar 17, 2018
1,402
Thank you. Just wondered if codeine, although far weaker than morphine, could be an alternative to stopping spasms and diarrhea, as morphine is not so easy to obtain.
You could, at the same time... with weaker opiates, I suggest adding scopolamine (in either hydrobromide pill form or datura inoxia seeds) to potentiate the CNS depressant and constipatory effects. Also, the use of scopolamine has antiemetic properties, which is actually the right antiemetic for cardenolide poisoning.
 
Bauhaus

Bauhaus

Specialist
Jan 18, 2020
388
Wouldn't morphine taking orally make you vomit since it's an opioid ?
And I doubt an antiemetic would help much, I mean we're talking about a huge amount of morphine.
Don't they give morphine IV in hospitals ?
And 1 g of a benzo might likely also cause vomiting.
Also odd they don't mention any antiemetic in this DDMP2 cocktail.
 
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DetachedDreamer97

DetachedDreamer97

Enlightened
Mar 17, 2018
1,402
Wouldn't morphine taking orally make you vomit since it's an opioid ?
And I doubt an antiemetic would help much, I mean we're talking about a huge amount of morphine.
Don't they give morphine IV in hospitals ?
And 1 g of a benzo might likely also cause vomiting.
Also odd they don't mention any antiemetic in this DDMP2 cocktail.
You know... that is actually a good point. It definitely will make you vomit. Though I think an antiemetic would work. But if in doubt, I'd suggest going triple-therapy. Metoclopramide for dopamine and serotonin, Odansetron for Serotonin, and Scopolamine (Kwells) for acetylcholine and arguably, serotonin.

As for why they don't mention antiemetics, I suspect they would expect you to already know. The bigger question on antiemetics is why they mention using Dramamine/Diphenhydramine, to use as an antiemetic for overdoses, but not scopolamine when its anticholinergic with histamine-blocking action and directly inhibits the vomiting centre.
 
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mini_weeny

mini_weeny

Every cradle is a grave
Jan 5, 2021
340
The newest cocktail is DDMA , A being amitriptilyne. I have about 150 A tablets but they expired in 2018 can they still work?
Also any substitutes for morphine?
Can I substitute diazepam for clonazepam or alprazolam??
 
Chesswiz2002

Chesswiz2002

Member
Jan 24, 2021
42
The newest cocktail is DDMA , A being amitriptilyne. I have about 150 A tablets but they expired in 2018 can they still work?
Also any substitutes for morphine?
Can I substitute diazepam for clonazepam or alprazolam??
How does Amitriptyline fit into the place which Propranolol occupied earlier? The latter is a beta-blocker while the former is a TCA (tricyclic antidepressant). I think Clonazepam would be better than Alprazolam, because it's longer acting and at least as potent.

Do you also by any chance, know where I can read more about the DDMA cocktail?
 
Butterfly65

Butterfly65

One step closer
Oct 28, 2020
157
You could, at the same time... with weaker opiates, I suggest adding scopolamine (in either hydrobromide pill form or datura inoxia seeds) to potentiate the CNS depressant and constipatory effects. Also, the use of scopolamine has antiemetic properties, which is actually the right antiemetic for cardenolide poisoning.
If one is taking these drugs to die relatively quick, I don't think constipation would be of a concern
 
DetachedDreamer97

DetachedDreamer97

Enlightened
Mar 17, 2018
1,402
If one is taking these drugs to die relatively quick, I don't think constipation would be of a concern
No, I mean... its effect in inhibiting gastric motility (or producing constipation) will be beneficial in increasing absorption of digoxin. Most poisons are better absorbed with decreased GI transit time, but the opposite is the case with cardiac glycosides.
 
A

Aap

Enlightened
Apr 26, 2020
1,856
@Chesswiz2002 , alprazolam is surprise in the ddmp context due to its faster onset. Diazepam is superior today both in that it has a fast onset and long duration of action

Regarding amitriptyline vs propranolol, the idea behind the amitriptyline is that it can cause fatal cardiac dysthymias. While propranolol can perhaps due this, it was included to prevent reflex tachycardia that will result from a breathing (and then circulatory) collapse from an opioid overdose.
 
Butterfly65

Butterfly65

One step closer
Oct 28, 2020
157
No, I mean... its effect in inhibiting gastric motility (or producing constipation) will be beneficial in increasing absorption of digoxin. Most poisons are better absorbed with decreased GI transit time, but the opposite is the case with cardiac glycosides.
You seem to really know your stuff. You should be a pharmacist or chemist. :)
 
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mini_weeny

mini_weeny

Every cradle is a grave
Jan 5, 2021
340
How does Amitriptyline fit into the place which Propranolol occupied earlier? The latter is a beta-blocker while the former is a TCA (tricyclic antidepressant). I think Clonazepam would be better than Alprazolam, because it's longer acting and at least as potent.

Do you also by any chance, know where I can read more about the DDMA cocktail?
I don't know if I can post the link since I already have a ban warning but it's out there on the internet.
I don't know if I can post the link since I already have a ban warning but it's out there on the internet.
I have the A and could get the C but my stomach is too sensitive and I can't take meto so I don't think it would work for me
 
Chesswiz2002

Chesswiz2002

Member
Jan 24, 2021
42
I don't know if I can post the link since I already have a ban warning but it's out there on the internet.

I have the A and could get the C but my stomach is too sensitive and I can't take meto so I don't think it would work for me
I've heard Domperidone works for people who have problems with Meto. 5HT3 antagonists like the 'setrons' could also be an option to look into.
 

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