It can be painful for many people to lack something they have a need for. People may begin to think that their life is not worth living. If someone is dissatisfied in their life, it can lead to them becoming suicidal. There is no escape from ourselves and our thoughts, apart from death. I think it can be worse if others have what we what we want and it can make us aware of what we dont have, when we see other people. Personally I would rather be alone, but I know that unfulfilled desires can ruin others lives.