Antiemetic for someone who takes Abilify

[Holacanthus]

I'm vacillating between N and SN as my method. In either case I'm going to have an antiemetic, because I know myself, and I will barf it up. Everyone here seems to talk about Meto (is that because it's easiest to get?) but I take Abilify.

I'm obviously not too worried about the long-term implications of mixing Abilify and Meto, but what about the short term ones? These two drugs have a MAJOR interaction. Could I even get through a 48-hour Meto regimen? It seems safest not to try to find out. I don't want to fail and then have permanent tardive dyskinesia.

Anyone have suggestions on what to use based on effectiveness and I can actually get it? Stan's guide has six antiemetics, presumably all dopamine antagonists - I'm down to five, most of which have only moderate interactions with Abilify but some of which don't seem to come up on the drug interaction trackers:

Dromperidone
Olanzapine
Alizapramide
Chlorpromazine
Prochlorperazine

Thanks!

 

[Holacanthus]

Bump in case last night's site issues kept anyone from replying.

If we can't bump, sorry!

 

[Backwood_tilt]

Since you're going to CTB, can you stop taking abilify beforehand?

I think it's half life is something like 72 hours so it should clear thru your system in a few days. You may still have some neurological adaptations to taking it that take time to wear off. Sorry I can't be of more help.

 

[NextSummer]

Aren't antipsychotics antiemetic? I take Risperidone and in Stans Guide, it says that no antiemetic drugs are necessary since it has antiemetic properties.

 

[Holacanthus]

The advice about stopping the Abilify is probably what I have to do. I'm just afraid I'll taper too quickly and have side effects, but what's the difference? The fact that I'm wondering this goes to my own readiness to take this step.

Abilify isn't one of the antipsychotics that stops nausea unfortunately.

 

[Quarky00]

I think it's half life is something like 72 hours so it should clear thru your system in a few days.

Never "stop" antipsychotics... Harsh withdrawal. It's not just about half-life. Taper over 2 weeks (and still may have issues).

Aren't antipsychotics antiemetic?

Not all. Stan researched this. You need receptor affinity. See FAQ:

Will any antiemetic work?	Must target dopamine Preferably serotonin as well
What are "The 13 Antipsychotics"?	Replace AE completely – ONLY if part of your regular health treatment. Stan listed meds with nM (receptor affinity). Higher numbers may indicate stronger effects.

~

Dromperidone

Domperidone (typo in guide). It's good. Any contraindications?

Why taper if you have AEs that work, with little interaction :)

 

[Holacanthus]

I can't tell if there are contraindications because domperidone doesn't seem to come up on the interactions trackers.