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niiiika

niiiika

Member.
Apr 14, 2026
13
Hey everyone, a late little thread. I wanted to ask about that long before actually but lately I been more serious about that. I have some pills from my doc like antidepressants and antipsychotics and wanted to ask if I take many of them like all the pills that are in the "package" can I die from it? And will it be very painful?

Thx for any opinions and answers!!!
 
MonkeyButter

MonkeyButter

Member
Sep 3, 2026
54
nope won't work. please see non-methods sticky thread
 
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A

abcdefg789

Experienced
May 8, 2026
203
also suggest you read the recommended thread. it won't work.

think about.... what company would sell a medicine that if you took the whole packet would result in the customer's death? No company would take such a risk.
 
niiiika

niiiika

Member.
Apr 14, 2026
13
also suggest you read the recommended thread. it won't work.

think about.... what company would sell a medicine that if you took the whole packet would result in the customer's death? No company would take such a risk.
But there have to be something, like od still happens and I heard you could get "poisoned" by it.
 
sadbh—itstimetogo🤎

sadbh—itstimetogo🤎

boofing advocate
Apr 4, 2026
615
Hi,

You're asking a few vague questions about whether unspecified antidepressants and antipsychotics will kill you and whether it would be painful.

To answer the first question, figure out the oral LD50 (lethal dose of 50% of said animal population) of each of your medications. LD50 will be given in mg/kg, so you'll need to calculate how many grams you would need to ingest in order to have a roughly 50% chance of dying. Then, determine whether you have that much medication on hand.

This would be your first step to determining if your meds can kill you.
Hi,

You're asking a few vague questions about whether unspecified antidepressants and antipsychotics will kill you and whether it would be painful.

To answer the first question, figure out the oral LD50 (lethal dose of 50% of said animal population) of each of your medications. LD50 will be given in mg/kg, so you'll need to calculate how many grams you would need to ingest in order to have a roughly 50% chance of dying. Then, determine whether you have that much medication on hand.

This would be your first step to determining if your meds can kill you.

For example, the oral LD50 of Tylenol in rats is 338 mg/kg. So if you weigh 150lb, you would have to ingest roughly 23g of Tylenol to have a roughly 50% chance of killing yourself.

50% you'd die, 50% chance you'd end up with life long liver problems (including liver failure). Most people don't like those odds (and Tylenol OD is notoriously unreliable), which is why it is considered a non method.

Hope this sheds some light into how to answer your questions.

Edit: further digging found that the LD50 of Tylenol for men is estimated to be ~400mg/kg.
 
Last edited:
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TaylorSwift0fficial

TaylorSwift0fficial

New Member
Aug 29, 2026
4
Both antidepressants and antipsychotics can theoretically work, but neither is advisable. Specially not antidepressants; even if it works, it isn't going to be peacefull. The most likely shot you have with antidepressants is to go by inducing a seratonin syndrom, which as I said earlier, is going to be far from peaceful.

A lot of antipsychotics though, tend to be also a CNS suppresent. Although they are considered a non-method here, if you take enough they can work. The problem is if they don't, the best case scenario is you will wake up in a hospital and have to go on with your life; the worst case scenario is you wake up in a hospital and have to go on with your life, while having permanent brain damage. The point is that we don't cosider it a risk worth taking here.
 
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niiiika

niiiika

Member.
Apr 14, 2026
13
Hi,

You're asking a few vague questions about whether unspecified antidepressants and antipsychotics will kill you and whether it would be painful.

To answer the first question, figure out the oral LD50 (lethal dose of 50% of said animal population) of each of your medications. LD50 will be given in mg/kg, so you'll need to calculate how many grams you would need to ingest in order to have a roughly 50% chance of dying. Then, determine whether you have that much medication on hand.

This would be your first step to determining if your meds can kill you.


For example, the oral LD50 of Tylenol in rats is 338 mg/kg. So if you weigh 150lb, you would have to ingest roughly 23g of Tylenol to have a roughly 50% chance of killing yourself.

50% you'd die, 50% chance you'd end up with life long liver problems (including liver failure). Most people don't like those odds (and Tylenol OD is notoriously unreliable), which is why it is considered a non method.

Hope this sheds some light into how to answer your questions.

Edit: further digging found that the LD50 of Tylenol for men is estimated to be ~400mg/kg.
Thanks!
Both antidepressants and antipsychotics can theoretically work, but neither is advisable. Specially not antidepressants; even if it works, it isn't going to be peacefull. The most likely shot you have with antidepressants is to go by inducing a seratonin syndrom, which as I said earlier, is going to be far from peaceful.

A lot of antipsychotics though, tend to be also a CNS suppresent. Although they are considered a non-method here, if you take enough they can work. The problem is if they don't, the best case scenario is you will wake up in a hospital and have to go on with your life; the worst case scenario is you wake up in a hospital and have to go on with your life, while having permanent brain damage. The point is that we don't cosider it a risk worth taking here.
Oh get it! Thank you for this informative answer!!
 

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