It's an A2 agonist. It is used in veterinary medicine to capture animals. It provides deep sedation without causing respiratory depression like GABA-A receptor agonists. It works in small doses. The version used in humans is dexmedetomidine. I have written about dexmedetomidine before. A2 agonists provide deep sedation at very high doses, causing bradycardia and hypotension. Dexmedetomidine is also a potent analgesic. While there are case reports documenting suicide attempts with this drug, it is a big gray area.
The procedural sedation induction dose of dexmedetomidine is only 1mcg/kg IV. However, I have read that an oral overdose requires a few grams. So yes, potent A2 agonists like xylazine and dexmedetomidine have the potential to offer the same standard of travel as N if orally is lethal.