Honestly I don't know why I post here anymore most of the time. There is zero reason to think plugging this will prevent nausea and vomiting. Likewise, I would assume that absorption of an inorganic salt is significantly worse in the rectum vs duodenum. Regardless of what has been posted in this thread, the primary location of SN absorption is not in the stomach, but rather the small intestine.
you are free to do what you want, but the questions regarding dose reduction don't coincide with anatomy or bioavailability. You are basically trying an untested route that may result in damage to your colon (reactive agents are nasty) and impaired absorption with the aim of accomplishing something (no nausea) that definitely will not be achieved. I'm not re arguing the mechanisms of N/V, but suffice to say they are both central and peripheral.
while it is tempting to listen to cheerleaders specifically, I would encourage you to also listen to the contrarians.