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wheelsonthebus

wheelsonthebus

vroom vroom
Apr 1, 2022
74
I'll go first.

Medications occasionally gave me the boost I needed to want to live:
  • Wellbutrin (bupropion, DNRI) gave me the ability to focus and the energy I needed to actually do what I told my body to do. For the fist time in my life, I was able to clean, keep organized, recall names and faces and what I ate that morning, study (and have it stick), and feel what I imagine "normal" is like. I didn't feel overly excited and was able to sleep just fine. It wasn't hard to switch tasks and I didn't get absorbed too long in interests that weren't what I needed to focus on in the moment. I think it still counts as hypomania though, as this was short lived. It lasted about a week and then I became "evil" - impulsive, non-reflective, making dumb decisions and blaming others despite being in the wrong. It was dangerous for me to drive, because I was selfish in my behaviors. I was extremely quick to frustrate and experienced frustration as rage. I quickly got off of this medication.
  • Lexapro (escitalopram, SSRI) did nothing for me except numb me, destroy what was left of my sex drive, and make me really sweaty.
  • Effexor XR (venlafaxine, SNRI) worked so damn well, but ultimately became ineffective as well, though I didn't become a villain this time. Upping the dose didn't return the positive effects, but did intensify the side effects, which were not tolerable to me: GI issues, really bad bruxism (teeth grinding) during the day and night, tremor, anxiety, high blood pressure, difficulty sleeping, no sex drive. Higher doses also left me appearing "wired." I titrated myself off.
In some ways, I wish I'd never been on any medication, since I wasted a full year of my life and ultimately failed to find work, a relationship, friendships, or earn any class credits for my premed (dropped so many classes) despite the temporary boosting effects. I'm actually worse off, and will never be a competitive applicant for medical school. I'm also many thousands of dollars poorer, due to no success with income.

Instead, I was left "chasing the dragon" of that high, that I realize must have been anti-depressant incurred hypomania, which I understand to be a common reaction. Since it levels out into numb depression again, but also with nasty withdrawal effects if I miss a dose, and also leaves side effects when I do take the medication, I see no benefit to continue to take antidepressants. I understand there is a genetic component at play, but I feel more damaged between trials and increasingly suicidal. I'm at the point that I don't even want to try to recover. I'm tired of this, grandpa. Let me out of the game!

I suspect it comes down to untreated ADHD. Not everything, of course, but this does seem like the underlying theme. Whenever I would raise this concern to my psychiatrist, he would say that his goal was to treat the "underlying depression" before assessing whether or not I had ADHD. I have also seen this take before between physicians in online discussion. This seems so odd to me, because while ADHD going untreated could absolutely lead to depression, it is not possible for depression to "cause" ADHD. (Much like Tylenol cannot cause autism.) I understand certainly that memory and attention and motivation can all be affected by depression, and issues with these are absolutely symptoms of ADHD in many people, so a depressed patient might exhibit certain signs that reduce or disappear when the depression is addressed but... I had exhibited the issues associated with ADHD and many more (that are not caused by depression) my entire life - these select few were just exacerbated in recent years. In other words, I've had ADHD symptoms before I was depressed, and I have no issue articulating why I feel depressed. It comes down to state-of-the-world issues in part, but my inability to take control of my life is the primary concern, which I expressed to the doctor. I have tried other psychiatrists, but they assume I am drug seeking. I am drug seeking, of course -- that is why you generally see a psychiatrist in their medication-management clinic. For medication.

I have never been prescribed Adderall, but the tiniest dosage (half or quarters of IR 5 mg blue pills) gave me great, manageable, not overly excited days when I took it, without diminishing effects, at least for the duration of my (elective) experiment. Similar returns with Ritalin. However, there's a lot of discussion recently from those who are prescribed Adderall or similar that it is no longer possible to find the real stuff, at least in the USA. There's theories that the recipe was changed for US distribution across all manufacturers, and honestly it seems to be the most likely cause, as Anne Milgram was the DEA Administrator during these times, and active ingrediate quotas during that period changed as well. Even if I could get a prescription without providers assuming intent to sell it or... I don't know, smoke it?... I don't know that it would do any good. Thoughts?
 
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UnrulyNightmare

UnrulyNightmare

Wanderer
Jul 3, 2024
469
I'm so sorry! It's so frustrating when psychiatrists get stuck in their own framework. And they simply do not understand that adhd can and will lead to a host of other complaints and comorbidities!! But that treating those morbidies is not gonna help because you're not actually treating the real cause..

Tried methylfenedate once and it was life changing. I could suddenly function and keep my train of thoughts!!! It was amazing how peaceful as well!
But due to side effects I couldn't keep taking it. :(

I did find a supplement the other day that have me a like wise feeling. Cognizin® Citicoline.

You could give it a try maybe?

Could you find/afford an adhd specialist/company instead of a general psychiatrist to get diagnosed?

These meds aren't all as safe 😖 might be nice to try them with some guidance.. As I understand you've been searching for!

If you wanna vent or chat more feel free to DM me 😊

I have no idea bout black market or street stuff or the compounds, sorry..
 
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wheelsonthebus

wheelsonthebus

vroom vroom
Apr 1, 2022
74
I'm so sorry! It's so frustrating when psychiatrists get stuck in their own framework. And they simply do not understand that adhd can and will lead to a host of other complaints and comorbidities!! But that treating those morbidies is not gonna help because you're not actually treating the real cause..

Tried methylfenedate once and it was life changing. I could suddenly function and keep my train of thoughts!!! It was amazing how peaceful as well!
But due to side effects I couldn't keep taking it. :(

I did find a supplement the other day that have me a like wise feeling. Cognizin® Citicoline.

You could give it a try maybe?

Could you find/afford an adhd specialist/company instead of a general psychiatrist to get diagnosed?

These meds aren't all as safe 😖 might be nice to try them with some guidance.. As I understand you've been searching for!

If you wanna vent or chat more feel free to DM me 😊

I have no idea bout black market or street stuff or the compounds, sorry..
Thank you for the reply! Yeah, Ritalin/methylfenedate seems like it might be promising because of it blocking the reuptake of dopamine and norepinephrine. I have taken citicoline with no response, unfortunately. Tried lion's mane, NAC, magnesium L threonate (often taken with citicoline), too, plus Vit D and Methyl B-12, and got nothing, but maybe you would benefit from some combo yourself!
 
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H

Hollowman

Empty
Dec 14, 2021
2,315
What made them not work? Nobody can answer that. Pharma companies don't even know why their neurotoxic poisons do the things they do.
 
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UnrulyNightmare

UnrulyNightmare

Wanderer
Jul 3, 2024
469
Thank you for the reply! Yeah, Ritalin/methylfenedate seems like it might be promising because of it blocking the reuptake of dopamine and norepinephrine. I have taken citicoline with no response, unfortunately. Tried lion's mane, NAC, magnesium L threonate (often taken with citicoline), too, plus Vit D and Methyl B-12, and got nothing, but maybe you would benefit from some combo yourself!
Ahh shit thats too bad :( yeah. Already on most of that or tried it.. Or at least what my body accepts without side effects. Weed? Maybe not best option tho.
 
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FoxSauce

FoxSauce

Emotionally unstable like an IKEA table
Aug 23, 2024
1,244
Hmmmm

● Prozac- made me more depressed and suicidal and drastic mood changes.

●Remeron - way to sleepy

●Vistaril - kept me dazed

● Wellbutrin- migranes like 3 in a week

● Melatonin- Works the next day (morning)

I use now : Buspar , Lithium and Effexor Xr
Trazodone too but I rarely use it.
 
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underairpressure

underairpressure

Member
Nov 30, 2025
63
I've tried a good handful of medications (vistaril, citalopram, zoloft, prozac, buspar, wellbutrin, etc), and the majority of them did literally nothing. Not even side effects, just....... nothing. Nada. Zilch.

Anti-psychotics, however? Those gave me such extreme tardive dyskinesia (uncontrollable twitching and spasming) that I couldn't function. I looked like I was possessed by a demon, my whole body just, violently writhing on the ground. I stopped them a long time ago and now only have the occasional facial twitch, but needless to say I'm terrified of ever touching psych drugs again. Ha.
 
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trashisland

trashisland

outsider
Aug 5, 2025
140
only ever tried sertraline, that did nothing. I just threw it away it's that pointless. I was only noticing side effects, no benefits. I got very restless which didnt exactly help my already existing sleeping issues. it just made me more annoyed and irritable, especially since I lost even more sleep. I dont even want to bother trying anything else
 
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gunmetalblue

gunmetalblue

Suicidal Jesus
Oct 31, 2025
405
- Quetiapine: I would be incapable of waking up
- Olanzapine: Made me a walking (or crawling) zombie
- Lithium: The shakes
- Tercian: Dry mouth and accelerated heart rate
- Setraline: Had no effect.
- Valium: Risk of gaining another addiction
 
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littlecutecorpse

littlecutecorpse

˚ʚ♡ɞ˚ absolute girlfailure ˚ʚ♡ɞ˚
Nov 13, 2025
171
just lexapro when i was younger. was only on it for a few weeks, but even when it was around the time where i was supposed to get the full benefit, all it did was fuck up my sex drive and made me nauseous as hell every morning. then had a bad headache and worse nausea, paired with severe depression, very high ideation, and later a panic attack shortly after unintentional withdrawal. somehow that faded not long after, but yeah....meds not for me. i know it was just one type of med, but i'd rather not deal with anymore bullshit with other meds after all of that
 
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