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rekt

Member
Jul 31, 2025
54
Here's the thing that confuses me about the SN protocol in PPH.

The protocol recommends taking oxazepam straight after drinking the SN, in order to lessen the unpleasant symptoms of ingesting SN and shorten the time to consciousness loss.

Here's the problem. The onset of action for oxazepam is said to be 30 to 60 minutes, while the symptoms of SN poisoning begin within 5 minutes after ingestion. Death is supposed to occur after 40 minutes.

How on earth is oxazepam supposed to help you if the effects of SN have run their course and you're already unconscious or dead by the time the oxazepam starts to work? Wouldn't it make more sense to take the oxazepam 30 minutes before you drink the SN?
 

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Forveleth

I knew I forgot to do something when I was 15...
Mar 26, 2024
4,017
You crush the tablets, which means you drastically shorten the time it takes for the medication to do its thing. Your stomach does not have to break down the outer coating first to get to the chemicals.

We should also be taking these after fasting so your stomach will not have anything else to digest so you can get to the medication faster. Most of the time when people take their pills they have at least some food in there that slows down the process.
 
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Obliviate

Obliviate

Abandon All Hope
Aug 13, 2022
1,011
Is this from the latest ppeh 2025 one?
 
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rekt

Member
Jul 31, 2025
54
Is this from the latest ppeh 2025 one?
Yes.
You crush the tablets, which means you drastically shorten the time it takes for the medication to do its thing. Your stomach does not have to break down the outer coating first to get to the chemicals.

We should also be taking these after fasting so your stomach will not have anything else to digest so you can get to the medication faster. Most of the time when people take their pills they have at least some food in there that slows down the process.
I see. But wouldn't it still be better to take the oxazepam a little bit before drinking the SN so that the effects have some to kick in before you drink the SN?
 
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Obliviate

Obliviate

Abandon All Hope
Aug 13, 2022
1,011
That's a really good question. Personally 20 tablets is a lot. People usually take benzos after so they don't fall asleep before getting to the SN. However I would take a couple before and a couple after to calm my nerves working up to taking SN.
You crush the tablets, which means you drastically shorten the time it takes for the medication to do its thing. Your stomach does not have to break down the outer coating first to get to the chemicals.

We should also be taking these after fasting so your stomach will not have anything else to digest so you can get to the medication faster. Most of the time when people take their pills they have at least some food in there that slows down the process.
This is a good point. Maybe that is why. But I would still take a couple before. I would follow the 2 day regimen instead of stat
 
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quietwoods

quietwoods

Easypeazylemonsqueezy
May 21, 2025
507
Yes.

I see. But wouldn't it still be better to take the oxazepam a little bit before drinking the SN so that the effects have some to kick in before you drink the SN?
You can but it's risky. The benzos will hit quickly and unexpectedly. I've seen two different failures where someone took benzos shortly before the SN and wasn't able to stay awake long enough.

1-2 minutes max before I would say.
 
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unluckysadness

unluckysadness

Enlightened
Jul 9, 2025
1,175
I have the same questions about the PPH and benzos. Another problem is propranolol. They are not sure if it's good or not. I have this med for my heart but if it slow down the process, it's not a good idea. But I'm also afraid with heart racing. And my body is used to take 20mg since many years, so I don't know if I should take it. Propranolol is very effective for me. I take it every morning and if I forget to take it, my heart beats faster in the early afternoon. I have diazepam intead of oxazepam but I think it's good too (maybe better because its fast action)
 
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cowboypants

cowboypants

From milkyway
May 7, 2024
576
it's a bit of a problem since we are diy-ing we have to bear it for a bit. I think the mixture will slam you after 10 minutes and hopefully you won't know any when the worst effects are hitting. For me, I want to be awake to take the second glass if needed. I'm looking for a time window of 10 minutes to be awake.
 
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fsteles

fsteles

Member
Aug 17, 2025
5
I think the same, since a clonazepam pill takes about 30 minutes to take effect.
Will this dose knock us sudenly?
I'm thinking of taking it and sitting down, reading something... When the first signs of sleepiness arrive, I'll take the SN.
Would it work like that?
 
diopdawe

diopdawe

Member
Mar 29, 2025
92
Very good question, i was wondering the same. In my own protocol, i will take benzos (clonazepam) 60 minutes before sn drink.
 
anonymous2025

anonymous2025

Still preparing to 🚍. 🌈
Apr 9, 2025
371
(You crush the tablets, which means you drastically shorten the time it takes for the medication to do its thing. Your stomach does not have to break down the outer coating first to get to the chemicals.)

I Was going to say the same thing. I use to like chewing my percs and I'd feel the effects within minutes.
 
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quietwoods

quietwoods

Easypeazylemonsqueezy
May 21, 2025
507
^ The above. PPH has designed protocols for a reason. Most failures that don't involve being found are due to deviating from protocol.

Follow the protocol. Crushed benzos can knock you out in minutes.
 
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Roadrunner

Roadrunner

Specialist
Mar 18, 2024
370
Very good question, i was wondering the same. In my own protocol, i will take benzos (clonazepam) 60 minutes before sn drink.
I'm not an expert but, I think 60 minutes before taking a bunch of crushed Clonazepam is way too long. You risk being knocked out and asleep before you get a chance to drink your SN, imho.
 
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swankysoup

swankysoup

Experienced
Feb 12, 2024
214
^ The above. PPH has designed protocols for a reason. Most failures that don't involve being found are due to deviating from protocol.

Follow the protocol. Crushed benzos can knock you out in minutes.
Does not using benzos increase risk a failure a lot?
 
D

derekWest

Experienced
Feb 1, 2025
268
If you take benzo before, the risk might be to fall asleep before drink sn ? But, I think your remark is interesting !
 
Lyn

Lyn

Momentary
Mar 1, 2025
301
I feel like benzos can act different for each individual.
I've seen people get knocked out in 10 minutes after a therapeutic dose of Alprazolam.

But I myself tried a mixture of 12.5mg Alprozolam (no tolerance, almost no prior use) crushed in a small amount of water and on an empty stomach.

I started feeling something only after 20-30 minutes. But several hours later I was still awake. I mean yeah, I was sedated pretty heavily, people noticed that my speech was slurred. But nothing more. I could even act as if I'm totally sober, no coordination issues etc.

Of course it wasn't a dose recommended in PPeH but it still was extremely high for a benzo naïve person like me.
At least it should have been. And even a smaller dose should have knocked me out quickly. But nothing.

So I am still trying to figure out the right dose and the timings for myself.
Maybe Xanax is not "my" benzo, or something. Maybe it was a paradoxical effect, which is also a thing if we're talking of benzos. I don't know.

But my overall point is that I too have my doubts about PPeH's recommended timing. It seems to be too dependent on individual response.
 
S

skywhywalker666

Member
Aug 5, 2025
29
A similar question is, if we take benzodiazepines after SN and we may immediately throw up, does this mean that the effect of benzodiazepines will be noticeably worse?
 

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