Method Soma as a Nembutal Substitute?

[voidlover777]

I do not believe I can get my hands on nembutal or any barbiturate. It seems that carisoprodal (pain o soma) is a potential substitute as its pharmacology is similar to barbiturates. Euthanasia doses of nembutal are 2000-10000mg. What would be the equivalent dose? As a prodrug, is it even possible to reach the desired concentrations of its active metabolite? I use 10-20 bags of fentanyl daily and am on 90mg methadone so opioids dont seem to work. And i dont want to try because I 1. Failing would lead to a shortage and 2. I don't want to use needles as my current batch is xylazine positive.

 

[LunarLight]

Soma doesn't work the same way as barbiturates. It would not be a peaceful death. Be aware of that.
That being said, I believe you need as much as >25g of Soma to CTB.

 

[rotciv]

Soma doesn't work the same way as barbiturates. It would not be a peaceful death. Be aware of that.
That being said, I believe you need as much as >25g of Soma to CTB.

Nailed it.

Post in thread 'What's in your suicide kit? I study pharmacology' https://sanctioned-suicide.net/thre...-kit-i-study-pharmacology.113882/post-2335715

I do not believe I can get my hands on nembutal or any barbiturate. It seems that carisoprodal (pain o soma) is a potential substitute as its pharmacology is similar to barbiturates. Euthanasia doses of nembutal are 2000-10000mg. What would be the equivalent dose? As a prodrug, is it even possible to reach the desired concentrations of its active metabolite? I use 10-20 bags of fentanyl daily and am on 90mg methadone so opioids dont seem to work. And i dont want to try because I 1. Failing would lead to a shortage and 2. I don't want to use needles as my current batch is xylazine positive.

You think that a high dose of fentanyl or other pontent nitazenes wouldn't work?

How many mgs are you consuming per day?

 

[voidlover777]

It says that carisoprodol overdose mirrors barbiturate overdose and that it is an agonist of GABA A at high doses. Why would it not work?

 

[LunarLight]

Nailed it.

Post in thread 'What's in your suicide kit? I study pharmacology' https://sanctioned-suicide.net/thre...-kit-i-study-pharmacology.113882/post-2335715

It's weird because here, it states that a 21g OD was near-fatal. However, the LD50 you gave for a mouse would mean that, so to say, you would need as much as 135g to kill half of 75-kg mice.

 

[voidlover777]

Nailed it.

Post in thread 'What's in your suicide kit? I study pharmacology' https://sanctioned-suicide.net/thre...-kit-i-study-pharmacology.113882/post-2335715


You think that a high dose of fentanyl or other pontent nitazenes wouldn't work?

How many mgs are you consuming per day?

Idk how strong my dope is but I use around 300mg a day + 90mg methadone. How much would you recommend i use at once?

 

[rotciv]

Idk how strong my dope is but I use around 300mg a day + 90mg methadone. How much would you recommend i use at once?

300mg of fetty??? That s**** must be cutted af..

A couple grams by boofing then..

 

[LunarLight]

Idk how strong my dope is but I use around 300mg a day + 90mg methadone. How much would you recommend i use at once?

300mg of F per day? And you're not dead?

And I thought I had a strong tolerance with 1,5g of H a day...

 

[voidlover777]

300mg of fetty??? That s**** must be cutted af..

A couple grams by boofing then..

Hopefully my next batch is xylazine negative like homie says it is cause im not tryna have a rectal ulcer.

 

[rotciv]

It's weird because here, it states that a 21g OD was near-fatal. However, the LD50 you gave for a mouse would mean that, so to say, you would need as much as 135g to kill half of 75-kg mice.

But mouses are more than 10x resilient than human.. and normally weigh 200/300 grams.

 

[voidlover777]

300mg of F per day? And you're not dead?

And I thought I had a strong tolerance with 1,5g of H a day...

im not a cartel chemist, as much as i'd love pure fentanyl its not available to most people anymore. Street fent is 80-99% cut

 

[LunarLight]

But mouses are more than 10x resilient than human..

Okay, I didn't know that! It's always time to learn something I guess.
So the LD50 for a 75kg human being would be around 13,5g. This is consistent.

im not a cartel chemist, as much as i'd love pure fentanyl its not available to most people anymore. Street fent is 80-99% cut

What is it cut with? You mentioned xylazine, but what else?

 

[rotciv]

im not a cartel chemist, as much as i'd love pure fentanyl its not available to most people anymore. Street fent is 80-99% cut

A friend told me when he found a pure source of Protonitazepyne went from 240mg to 10mg

 

[voidlover777]

A friend told me when he found a pure source of Protonitazepyne he went from 240mg to 10mg

Nitazenes are bunk ime, i ate a gram of chinese NDI and woke up. Sniffing coke sized lines of NDE barely kept me from shitting myself.

Okay, I didn't know that! It's always time to learn something I guess.
So the LD50 for a 75kg human being would be around 13,5g. This is consistent.

What is it cut with? You mentioned xylazine, but what else?

what makes u think i'd know that? I use test strips not drugsdata

 

[LunarLight]

what makes u think i'd know that? I use test strips not drugsdata

Sorry, where I live there are centers where you can test your drugs for free.

 

[rotciv]

Nitazenes are bunk ime, i ate a gram of chinese NDI and woke up. Sniffing coke sized lines of NDE barely kept me from shitting myself.

N-desethyletonitazene?? 10 times stronger than fetty they say

It must be cutted af..

 

[voidlover777]

N-desethyletonitazene?? 10 times stronger than fetty they say

It must be cutted af..

N-desethyl isotonitazene is 10 times stronger than fentanyl, n desethyl Etotonitazene is weaker than fent.

 

[rotciv]

Frontiers | “Tranq-dope” overdose and mortality: lethality induced by fentanyl and xylazine

The recreational use of fentanyl in combination with xylazine (i.e., "tranq-dope") represents a rapidly emerging public health threat characterized by signif...

www.frontiersin.org

"Results: A nonlethal dose of fentanyl (56 mg/kg) produced an approximately 5-fold decrease in the estimated LD50 for xylazine (i.e., the dose estimated to produce lethality in 50% of the population). Notably, a nonlethal dose of xylazine (100 mg/kg) produced an approximately 100-fold decrease in the estimated LD50 for fentanyl. Both drug combinations produced a synergistic interaction as determined via isobolographic analysis. The opioid receptor antagonist, naloxone (3 mg/kg), but not the alpha-2 adrenergic receptor antagonist, yohimbine (3 mg/kg), significantly decreased the lethality of a fentanyl-xylazine combination. Lethality was rapid, with death occurring within 10 min after a high dose combination and generally within 30 min at lower dose combinations. Males were more sensitive to the lethal effects of fentanyl-xylazine combinations under some conditions suggesting biologically relevant sex differences in sensitivity to fentanyl-xylazine lethality."

I do not believe I can get my hands on nembutal or any barbiturate. It seems that carisoprodal (pain o soma) is a potential substitute as its pharmacology is similar to barbiturates. Euthanasia doses of nembutal are 2000-10000mg. What would be the equivalent dose? As a prodrug, is it even possible to reach the desired concentrations of its active metabolite? I use 10-20 bags of fentanyl daily and am on 90mg methadone so opioids dont seem to work. And i dont want to try because I 1. Failing would lead to a shortage and 2. I don't want to use needles as my current batch is xylazine positive.

The LD50 in rats of xylazine (130mg/kg) and pentobarbital (118mg/kg) is practically the same, much better to use xylazine instead of carisoprodol, a difference of more than 7x in lethality..

https://edition.cnn.com/2022/03/17/health/xylazine-tranq-overdose/index.html?fbclid=IwAR31uha_34mA1YpTGH65WgriUYTo7kNKuKXdNbc-NDJK2ww1HkzgJqGDoHU