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Exiled spirit

Student
Dec 25, 2019
113
I read that people with slow digestive system aren't suitable for SN method because if they took SN, a large portion of it would be converted by gastric acid into sodium nitrate before being released into bloodstream. So, there wouldn't be enough SN to do the job.. Is that true? And how do I know if i have this health problem?
 
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Busridin'26

Busridin'26

Hating every minute of being alive.
Dec 8, 2019
1,933
Following & commenting bc I am wondering the same thing.
 
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Pale_Rider

Pale_Rider

Enlightened
Apr 21, 2025
1,470
Great cause sodium nitrite is gonna do the dirty deed. lol
 
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Forever Sleep

Earned it we have...
May 4, 2022
15,350
DIgestive issues are something I'm worried about too. Specifically, I wonder if having no gall bladder affects the amount of bile floating about and, how that may affect things.

I think the antacid medication in the original protocol was there to reduce the acid. They seemed to have stopped recommending it but, maybe it's worth considering if we feel like our systems are particularly acidic. Obviously, it's not scientific advice here. More like guess work.
 
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D

DOHARDTHINGS24

Warlock
Apr 30, 2024
709
DIgestive issues are something I'm worried about too. Specifically, I wonder if having no gall bladder affects the amount of bile floating about and, how that may affect things.
And tonight's insomnia is brought to me by ⬆️ 🤣
 
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Xiaojiu

Xiaojiu

cease to exist 不复存在
Mar 28, 2025
678
DIgestive issues are something I'm worried about too. Specifically, I wonder if having no gall bladder affects the amount of bile floating about and, how that may affect things.

I think the antacid medication in the original protocol was there to reduce the acid. They seemed to have stopped recommending it but, maybe it's worth considering if we feel like our systems are particularly acidic. Obviously, it's not scientific advice here. More like guess work.
Thanks for pointing that out. I don't have a gallbladder either :(
 
F

Forever Sleep

Earned it we have...
May 4, 2022
15,350
And tonight's insomnia is brought to me by ⬆️ 🤣
Sorry!
Thanks for pointing that out. I don't have a gallbladder either :(

I'm not even certain it will affect things. I read that bile was alkaline rather than acidic. Maybe our systems work the same as regular ones though. Just that the bile comes directly from the liver.
 
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InTheAbyss

Student
Jul 30, 2024
147
Also posting to follow. Both about people with slow digestion and the concerns of taking sn for those also taking ozempic. I heard that ozempic alone can slow gastric emptying and can even cause gastric paralysis. Compounded by already having slow gastric emptying to begin with.
 
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Esc9434

Specialist
Feb 25, 2020
301
Sorry!


I'm not even certain it will affect things. I read that bile was alkaline rather than acidic. Maybe our systems work the same as regular ones though. Just that the bile comes directly from the liver.
You have brought up some good points in this thread about no gallbladder and bile acidity, my friend.

Okay, so we take antacids to reduce the conversion to nitrate before it leaves our stomach.

However, our bile is acidic too, so that will aid in the conversion too.

I guess that's why we take a lot of SN, so this conversion slows down and lets the nitrite hit our kidneys, then into our bloodstream.

I'm just throwing shit at the wall here.

You are becoming my new favorite poster btw :happy:.
 
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Zoro1029

Member
Mar 15, 2025
87
I believe that is why fasting and the AE are important in the protocol. Fasting lets the SN hit your system faster and the AE helps absorption. I have my AE and would feel uncomfortable trying the method without it.

I do have ulcerative colitis which is a disgestive disease but I think my disgestion is normal otherwise. The one disease which I believe makes it really hard is gastoparesis which a user here had and was unable to CTB. I think for most people as long as you follow the protocol and arent found early it should be enough for you. Also why preparing multiple doses is important but even then i dont think it is necessary for most.
 
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martinso67

All human rights are important
Feb 5, 2021
362
I read that people with slow digestive system aren't suitable for SN method because if they took SN, a large portion of it would be converted by gastric acid into sodium nitrate before being released into bloodstream. So, there wouldn't be enough SN to do the job.. Is that true? And how do I know if i have this health problem?
That's why metoclopramide is recommended instead of other anti-emetics. It has the strongest gastric emptying effect of any anti emetic medication. It will speed up the gastric emptying. Also fasting for several hours is recommended.

I think that fear is very irrational. In my opinion the possible failures that could happen with the SN method is:
- that you still puke out everything regardless of taking SN.
- or the side effects of SN (that are not really bad) cause you much anxiety that you call for emergency or any ambulance
 
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InTheAbyss

Student
Jul 30, 2024
147
That's why metoclopramide is recommended instead of other anti-emetics. It has the strongest gastric emptying effect of any anti emetic medication. It will speed up the gastric emptying.
Do you happen to know how close domperidone comes to meto for gastric emptying? I couldn't get meto because it could react to other meds I'm taking and might cause seritonin syndrome which they told me wasn't a good thing.
 
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Zoro1029

Member
Mar 15, 2025
87
Do you happen to know how close domperidone comes to meto for gastric emptying? I couldn't get meto because it could react to other meds I'm taking and might cause seritonin syndrome which they told me wasn't a good thing.
Just FYI I think Serotonin syndrome is very rare and I think taking Meto at the time of your CTB wont be a real risk as long as its the only time you take it. Its only a risk if you consistently take something like Meto over a period of time that serotonin syndrome becomes a risk.

I did a test run with Meto I just skipped my SNRI and Lithium dose to avoid any interaction. Wasnt too bad.

 
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InTheAbyss

Student
Jul 30, 2024
147
Just FYI I think Serotonin syndrome is very rare and I think taking Meto at the time of your CTB wont be a real risk as long as its the only time you take it. Its only a risk if you consistently take something like Meto over a period of time that serotonin syndrome becomes a risk.

I did a test run with Meto I just skipped my SNRI and Lithium dose to avoid any interaction. Wasnt too bad.

You're probably right about it not being a real risk for just ctb. But for me the meto was going to be a long term prescription and the doc asked the pharmacy to check for interactions in my meds. They had that come up so they didn't want to give out the meto and had the doc change it to domp which could 'only' cause heart problems instead.

I'm not sure how to get it like you did. Like where to find those legit online pharmacies and get that without my docs knowing. What I got I got because I legit need the ae for gastric emptying and will be on them for life most likely.

I tried 6x10 domp similar to like you did. I didn't hear anything but I did feel my body or at least my head heating up for about an hour after taking them. My resting heart rate is pretty fast as it is so it'd have to jump up insanely high for me to feel it at all.
 
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divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,919
Also posting to follow. Both about people with slow digestion and the concerns of taking sn for those also taking ozempic. I heard that ozempic alone can slow gastric emptying and can even cause gastric paralysis. Compounded by already having slow gastric emptying to begin with.
Good question I was wondering this to
 
Amarajoy

Amarajoy

Specialist
Sep 12, 2024
390
I believe that is why fasting and the AE are important in the protocol. Fasting lets the SN hit your system faster and the AE helps absorption. I have my AE and would feel uncomfortable trying the method without it.

I do have ulcerative colitis which is a disgestive disease but I think my disgestion is normal otherwise. The one disease which I believe makes it really hard is gastoparesis which a user here had and was unable to CTB. I think for most people as long as you follow the protocol and arent found early it should be enough for you. Also why preparing multiple doses is important but even then i dont think it is necessary for most.
Did they actually attempt sn with gastroporesis?
 
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