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emptybox

emptybox

Member
Nov 27, 2022
43
For now SN is my chosen method, I know it's usually a bad idea to change "the protocol"; that's why I'm asking before doing anything:

Does it make sense to use propofol before/(most likely)right after ingesting SN?
The purpose is to go unconscious as soon as possible after ingesting SN. As I know, it can take a few minutes for propofol to knock you out.
Going to use IV cannula + a syringe
I got 1500mg of propofol but if 2.5mg/1kg is needed for anesthesia, I'll need only ~125mg (?!)
What happens If I use more "just in case" considering SN is the main thing that is supposed to kill me? Longer sedation?

*Is Propofol-only for CBT really that complicated if I can administer it myself using an IV cannula? I have stuff for infusions too but I'm afraid to fail. But from what I read, you can't administer it fast in amount that can kill you(1-2g) because it ruins veins/something else? So infusion system is necessary. Is it worth learning and preparing better to use Propofol only, instead of SN?

I read what the forum offers for this topic, wanted to get more information specifically for SN method. But any information is appreciated, thank you in advance.
 
R

randy

Student
Jan 6, 2023
155
it can take a few minutes for propofol to knock you out.
I've had propofol in the hospital. It takes about 10-15 seconds for it to knock you out. It is really fast
 
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Sunset Limited

Sunset Limited

I believe in Sunset Limited
Jul 29, 2019
1,352
Propofol is a hard route to CTB. The anesthesia induction dose of propofol makes you unconscious for 10 minutes. 200mg can be injected prior to knock down. This dose could kill someone. If the airway collapses. If you can protect your airway, spontaneous breathing will return. You will wake up in 10 minutes. The induction dose of propofol causes apnea. Then shallow breathing. Waking up with pulmonary edema. For 40% - 50% methemoglobinemia, you need more than 10 minutes. The best method is an infusion, not a bolus. 200 mg bolus + 30 mg/min infusion good idea. This makes you unconscious for more than 40 minutes. It seems to be enough for 40% methemoglobinemia. I will make a thread about propofol soon. I wish the best for you.
 
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emptybox

emptybox

Member
Nov 27, 2022
43
Propofol is a hard route to CTB. The anesthesia induction dose of propofol makes you unconscious for 10 minutes. 200mg can be injected prior to knock down. This dose could kill someone. If the airway collapses. If you can protect your airway, spontaneous breathing will return. You will wake up in 10 minutes. The induction dose of propofol causes apnea. Then shallow breathing. Waking up with pulmonary edema. For 40% - 50% methemoglobinemia, you need more than 10 minutes. The best method is an infusion, not a bolus. 200 mg bolus + 30 mg/min infusion good idea. This makes you unconscious for more than 40 minutes. It seems to be enough for 40% methemoglobinemia. I will make a thread about propofol soon. I wish the best for you.
Thank you very much! The best for you too.
 
born2win

born2win

Time is a flat circle
Jun 5, 2022
159
do
Propofol is a hard route to CTB. The anesthesia induction dose of propofol makes you unconscious for 10 minutes. 200mg can be injected prior to knock down. This dose could kill someone. If the airway collapses. If you can protect your airway, spontaneous breathing will return. You will wake up in 10 minutes. The induction dose of propofol causes apnea. Then shallow breathing. Waking up with pulmonary edema. For 40% - 50% methemoglobinemia, you need more than 10 minutes. The best method is an infusion, not a bolus. 200 mg bolus + 30 mg/min infusion good idea. This makes you unconscious for more than 40 minutes. It seems to be enough for 40% methemoglobinemia. I will make a thread about propofol soon. I wish the best for you.
you recommend taking 400gms of Inderal Proponalol alongside 30gms of SN?
 
emptybox

emptybox

Member
Nov 27, 2022
43
do

you recommend taking 400gms of Inderal Proponalol alongside 30gms of SN?
@Sunset Limited is taking about Propofol, not Propranolol here; it seems like you could misinterpret but if not, I'm sorry!

From what I know taking Propranolol for SN method isn't necessary or even recommended anymore(or it's only if you have benzo?), it's controversial.
This thread seems useful.
I'm also interested in how to use Propranolol with SN, especially without benzo-s. And Propranolol alone, too.
 
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freelifexit

freelifexit

Specialist
Nov 7, 2021
391
Propofol will make you sleep only for 5-10 minutes, than you will wake up and feel symptoms of SN. Sometimes they are peaceful, sometimes they painful. Usually it takes 15-40 minutes to lose consciousness with SN.

Unfortunately it is really hard to die by only injecting propofol, because you need very big amount of it, which can not be injected quickly enough. However Michael Jackson died from small amount of propofol.
 
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LocalAngel

LocalAngel

Lost, wanting out.
Feb 7, 2023
214
Propofol will make you sleep only for 5-10 minutes, than you will wake up and feel symptoms of SN. Sometimes they are peaceful, sometimes they painful. Usually it takes 40 minutes to lose consciousness with SN.
Where did you get this information, sorry? I usually see 12-20 minutes, not 40.
 
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LocalAngel

LocalAngel

Lost, wanting out.
Feb 7, 2023
214
I think it is from 15 to 40 minutes, also it depends on dose.
Again, do you have a source for this information? Primarily asking because 40 minutes sounds like absolute hell- and i thought 45 was minimum before CTB. Thanks for responding.
 
L

lukas19

Specialist
Jan 17, 2023
345
Again, do you have a source for this information? Primarily asking because 40 minutes sounds like absolute hell- and i thought 45 was minimum before CTB. Thanks for responding.
Same here, very very dubious about his figures. Contradicts Stan's megathread about SN and every pretty much every story i have read about.
 
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freelifexit

freelifexit

Specialist
Nov 7, 2021
391
Again, do you have a source for this information? Primarily asking because 40 minutes sounds like absolute hell- and i thought 45 was minimum before CTB. Thanks for responding.
In this document where failed attempts collected there are two cases:
1. "drakewantstogo" took more than 45 minutes to lose consciousness
2. "querry1" took 1 hour to lose consciousness

I saw a few more posts where people wrote that they lost consciousness in 30-40 minutes, but I can't find them.
 
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LocalAngel

LocalAngel

Lost, wanting out.
Feb 7, 2023
214
Both of those doses they threw up at, and was at lower doses, below the normal 25g, with no secondary drink. Though that is very interesting information, thank you.
In this document where failed attempts collected there are two cases:
1. "drakewantstogo" took more than 45 minutes to lose consciousness
2. "querry1" took 1 hour to lose consciousness

I saw a few more posts where people wrote that they lost consciousness in 30-40 minutes, but I can't find them.
 
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Sunset Limited

Sunset Limited

I believe in Sunset Limited
Jul 29, 2019
1,352
Propofol will make you sleep only for 5-10 minutes, than you will wake up and feel symptoms of SN
Actually, someone who injects himself with 200mg of propofol has a greater than 70% chance of dying. This dose exceeds the plasma concentration of 10 mcg/ml. Few people can protect the airway at this concentration. Adding to the hemodynamic effects of rapid-injection propofol, 200mg of propofol is fatal for most people but still no guarantee ofc.
 
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emptybox

emptybox

Member
Nov 27, 2022
43
@freelifexit thank you
Actually, someone who injects himself with 200mg of propofol has a greater than 70% chance of dying. This dose exceeds the plasma concentration of 10 mcg/ml. Few people can protect the airway at this concentration. Adding to the hemodynamic effects of rapid-injection propofol, 200mg of propofol is fatal for most people but still no guarantee ofc.
Is 200mg maximum amount one can inject without hurting a vein/lungs/etc.? Is that why this specific number used?

My Propofol solution is 50mg/1ml so it can't be used for infusions unless I combine it with another solution to get needed volume
It's only 30ml that contain 1500mg of Propofol + 1500mg Lidocaine, if I understand it right(seems suspicious?)
This specific one is used for eutanasia (animals), 1ml/2.5-5kg, but apparently it's for small animals like cats and dogs, I don't weight like a dog so I need 10-20ml at least(1-2 bottles) and then it's a problem. Someone here said they use 1-2g which would be 2-4 bottles. A 15kg dog needs 3-6ml which is not even a bottle, 4.5kg cat needs only 0.9-1.8ml, so of course it's different. But I also find these amounts weird... I'm probably making a mistake here.

Anyway I guess infusion is the only way to make it somewhat reliable. I can't inject it fast enough even with two IV cannula(s) in two different places. As you said:
2 x IV access and 15 minutes drip infusion does the job. The maximum flow rate of a gravity fed drip infusion is 6-8 ml/min. That's an average of 150mg/min propofol with two IV accesses. It should flow for 15 minutes, so 2200mg of propofol is needed. Of course less propofol based on your weight and other parameters might also do the job but the drip infusion system is unreliable. Many times I have seen the flow stop for no apparent reason. Propofol is hard route to CTB.
Combined with SN, it would at least work in case an infusion system messes up, even if the plan to stay unconscious during the process fails I guess the chance that some of it will do the job is bigger anyway? Now I'm just interested in thinking about it, not sure if it's worth risking.

I know combining methods isn't a good idea, it just makes it more complicated and unpredictable. At this point I'm just thinking out loud and trying to understand what options I have.
 
Sunset Limited

Sunset Limited

I believe in Sunset Limited
Jul 29, 2019
1,352
@freelifexit thank you

Is 200mg maximum amount one can inject without hurting a vein/lungs/etc.? Is that why this specific number used?

My Propofol solution is 50mg/1ml so it can't be used for infusions unless I combine it with another solution to get needed volume
It's only 30ml that contain 1500mg of Propofol + 1500mg Lidocaine, if I understand it right(seems suspicious?)
This specific one is used for eutanasia (animals), 1ml/2.5-5kg, but apparently it's for small animals like cats and dogs, I don't weight like a dog so I need 10-20ml at least(1-2 bottles) and then it's a problem. Someone here said they use 1-2g which would be 2-4 bottles. A 15kg dog needs 3-6ml which is not even a bottle, 4.5kg cat needs only 0.9-1.8ml, so of course it's different. But I also find these amounts weird... I'm probably making a mistake here.

Anyway I guess infusion is the only way to make it somewhat reliable. I can't inject it fast enough even with two IV cannula(s) in two different places. As you said:

Combined with SN, it would at least work in case an infusion system messes up, even if the plan to stay unconscious during the process fails I guess the chance that some of it will do the job is bigger anyway? Now I'm just interested in thinking about it, not sure if it's worth risking.

I know combining methods isn't a good idea, it just makes it more complicated and unpredictable. At this point I'm just thinking out loud and trying to understand what options I have.
200mg = 20cc containing 1% propofol. With a large vein and a large cannula, it is possible to push 20-25 cc in 10 seconds. I assume you have anestophole. 1ml = 50mg of propofol + 50mg of lidocaine. I have answered this question before.

"Anestofol is a really interesting drug. I don't understand how they mixed propofol and lidocaine. Propofol is a hydrophobic phenol. It is insoluble in water but soluble in oil. So injectable propofol is an oil emulsion. If you add lidocaine to the emulsion, the emulsion will be broken. 5% propofol is an ideal rate for euthanasia 1000mg/20ml. Someone can inject themselves with 20 ml of anestofol before that person gets knocked down. If 1000mg of propofol is injected rapidly, it will certainly cause cardiovascular collapse followed by profound hypotension. It also contains 1 gram of lidocaine! potent negative inotropic. It is used in the treatment of ventricular fibrillation. While 1 gram of lidocaine alone is not a high enough dose to cause sudden cardiac arrest, with 1 gram of propofol it is an absolutely deadly combination for the average person."

So if someone survives injections of 1000mg propofol + 1000mg lidocaine, I would consider him to be from the kryptonian planet. The anesthesia induction dose of propofol in animals is 12-15 mg/kg, while it is 2 mg/kg in humans. With premedication. So animal and human requirement are different. Still I think infusion is best route. Do not rush. Try to learn more about propofol. Remember, I am not an expert, but I am sharing data from scientific studies. My method is propofol too, so I have to research about it. I wish the best for you.
 
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emptybox

emptybox

Member
Nov 27, 2022
43
200mg = 20cc containing 1% propofol. With a large vein and a large cannula, it is possible to push 20-25 cc in 10 seconds. I assume you have anestophole. 1ml = 50mg of propofol + 50mg of lidocaine. I have answered this question before.

"Anestofol is a really interesting drug. I don't understand how they mixed propofol and lidocaine. Propofol is a hydrophobic phenol. It is insoluble in water but soluble in oil. So injectable propofol is an oil emulsion. If you add lidocaine to the emulsion, the emulsion will be broken. 5% propofol is an ideal rate for euthanasia 1000mg/20ml. Someone can inject themselves with 20 ml of anestofol before that person gets knocked down. If 1000mg of propofol is injected rapidly, it will certainly cause cardiovascular collapse followed by profound hypotension. It also contains 1 gram of lidocaine! potent negative inotropic. It is used in the treatment of ventricular fibrillation. While 1 gram of lidocaine alone is not a high enough dose to cause sudden cardiac arrest, with 1 gram of propofol it is an absolutely deadly combination for the average person."

So if someone survives injections of 1000mg propofol + 1000mg lidocaine, I would consider him to be from the kryptonian planet. The anesthesia induction dose of propofol in animals is 12-15 mg/kg, while it is 2 mg/kg in humans. With premedication. So animal and human requirement are different. Still I think infusion is best route. Do not rush. Try to learn more about propofol. Remember, I am not an expert, but I am sharing data from scientific studies. My method is propofol too, so I have to research about it. I wish the best for you.
Didn't see this message about Anestofol before, thank you very much again. Even if you're not an expert, you're helpful. There's a lot to think about, thank you for navigating. Wishing you strength and patience with your method too, with your smart attitude it should be fine eventually
 
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E

Escapee

Student
Jan 14, 2023
163
Actually, someone who injects himself with 200mg of propofol has a greater than 70% chance of dying. This dose exceeds the plasma concentration of 10 mcg/ml. Few people can protect the airway at this concentration. Adding to the hemodynamic effects of rapid-injection propofol, 200mg of propofol is fatal for most people but still no guarantee ofc.
Thank you very much for your info can you please pm me links where I can learn more about propofol method. I know you made a lot of research can you share your sources with me please?you can email me or send me through telegram what ever way you want. I just want to be sure the 2000 mg of propofol I am preparing can send me peacefully to the other side of life. Anyone else with sources is also most welcome
@freelifexit thank you

Is 200mg maximum amount one can inject without hurting a vein/lungs/etc.? Is that why this specific number used?

My Propofol solution is 50mg/1ml so it can't be used for infusions unless I combine it with another solution to get needed volume
It's only 30ml that contain 1500mg of Propofol + 1500mg Lidocaine, if I understand it right(seems suspicious?)
This specific one is used for eutanasia (animals), 1ml/2.5-5kg, but apparently it's for small animals like cats and dogs, I don't weight like a dog so I need 10-20ml at least(1-2 bottles) and then it's a problem. Someone here said they use 1-2g which would be 2-4 bottles. A 15kg dog needs 3-6ml which is not even a bottle, 4.5kg cat needs only 0.9-1.8ml, so of course it's different. But I also find these amounts weird... I'm probably making a mistake here.

Anyway I guess infusion is the only way to make it somewhat reliable. I can't inject it fast enough even with two IV cannula(s) in two different places. As you said:

Combined with SN, it would at least work in case an infusion system messes up, even if the plan to stay unconscious during the process fails I guess the chance that some of it will do the job is bigger anyway? Now I'm just interested in thinking about it, not sure if it's worth risking.

I know combining methods isn't a good idea, it just makes it more complicated and unpredictable. At this point I'm just thinking out loud and trying to understand what options I have

I am in the same situation as you are. It makes things less complicated if we can help each other. My method is propofol I am preparing 2000 mg please update me if you can find helpful info about it I will do the same. We can pm each other. Good luck. Same goes for anyone who had propofol as their method.Good luck
 
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