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creatureoflight

Mage
Jul 27, 2018
529
"I don't think neither of these cases are ideal references. Both subjects ingested fairly small amounts, with the woman only taking one gram (yet still dying!) and the man taking a moderate dose at 15g. Both significantly less than 30g."
Are you aware that Nitschke recommends 15g?

Summary
Sodium nitrite isnt my method because i dont consider it a reliable enough for self deliverance, my fear of become a vegetable is in par with phobia. The method is not as reliable in humans in comparison to pigs because human methemoglobin reducatse system is more effective in converting methemoglobin back to hemoglobin (with a half life of 1-3 hours). Even the man that suggested the method, Nitschke, claims that it only scores 7 out of 10 on his reliability test. Its low reliability makes it dangerous, because the method deprives your brain of oxygen and you could potentially end up with severe brain damage. And studies show it might be somewhat difficult achieve lethal levels methemoglobin (above 70%) when sodium nitrite ingestion from 0.4 to > 200 mg/kg only reaches methemoglobinemia levels of 7.7 up to 79%.

Nitschkes credibility
*Increasing dosage in later editions
*Rates sodium azide 5/5 in speed despite several scientific articles depicting azide in painful outdrawn process over hours or days. Then Nitshcke claims that SN rates 3/5 in speed test. Nitschke also claims SN is less powerful then sodium azide. We have seen some evidence that contradicts: PPH says unconscious after 12 mins for a 15 grams dose.

If you still want try it i suggest using my prescription above.

Anyway i hope you reached a greater understanding of SN.

Verdic
SN is a social club.

Then I suppose I interpreted his graph wrong? I couldn't even find the source off of which he got it.
 
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OfficerK

Experienced
May 6, 2018
255
"I don't think neither of these cases are ideal references. Both subjects ingested fairly small amounts, with the woman only taking one gram (yet still dying!) and the man taking a moderate dose at 15g. Both significantly less than 30g."
Are you aware that Nitschke recommends 15g?

Summary
Sodium nitrite isnt my method becouse i dont consider it a reliable method of self deliverance. The method is not as reliable in humans in comparison to pigs because human methemoglobin reducatse system is more effective in converting methemoglobin back to hemoglobin (with a half life of 1-3 hours). Even the man that suggested the method, Nitschke, claims that it only scores 7 out of 10 on his reliability test. Its low reliability makes it dangerous, because the method deprives your brain of oxygen and you could potentially end up with severe brain damage. And studies show it might be somewhat difficult achieve lethal levels methemoglobin (above 70%) when sodium nitrite ingestion from 0.4 to > 200 mg/kg only reaches methemoglobinemia levels of 7.7 up to 79%.

Nitschkes credibility
*Increasing dosage in later editions
*Rates sodium azide 5/5 in speed despite several scientific articles depicting azide in painful outdrawn process over hours or days. Then Nitshcke claims that SN rates 3/5 in speed test. Nitschke also claims SN is less powerful then sodium azide. We have seen some evidence that contradicts: PPH says unconscious after 12 mins for a 15 grams dose.

If you still want try it i suggest using my prescription above.

Anyway i hope you reached a greater understanding of SN.

Verdic
SN is a social club.

Yes, I know he recommends 15 grams. I was first and foremost talking referring to the 17-year old woman, although I see that I probably shouldn't have included the man in the same sentence. My point when it comes to them receiving medical attention still stands, however. If we assume that the 28 year old was in normal physical condition for someone his age, I would say that "transient loss of consciousness" within an hour after ingesting the standard dose seems to be fairly close to what EXIT claims.

I agree that his 5/5 claim is a bit dubious, but I would also say that there's a big difference between inaccurately estimating how a drug/substance works, and actually lying about test results. I think it's important to remember that the PPH is primarily written for elderly and/or terminally ill people, who are far more frail and sensitive to overdosing. The book doesn't claim that 12 minutes +/- is accurate for everyone, it is simply an example from an individual that was probably part of their intended audience.

Also, I would think that it is harder to come by cases where everything went as planned, i.e. where the subject went undiscovered for a long time and there was no apparent vomiting or expressed suffering. Medical personnel would be most interested in writing about cases that they can actually extract useful information from, e.g. what kind of treatment that worked or didn't work.

I'm not at all disputing your suggestion about taking a larger dose. You're also definitely right that it could cause brain damage, and that's part of why I'm personally still waiting to go through with it. Hopefully EXIT will be able to produce some more reliable data in the coming months.
 
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HannibalLector

Student
Jul 5, 2018
161
I'm really confused by Nitschkes video. At 12:17, he shows the activity of Mehb reductase in different animals. Below, you can see the lethal gavage dose in mg pro kilo. The dot that represents the human is somewhere before the pig? So doesn't this mean that actually Mehb is less effective in humans than in pigs? Rats seem to be way more effective at processing this poison than humans as they are on the right. Or am I interpreting this completely wrong?

Nitschkes diagram is confusing, if he made his conclusions from that im not surprised of his recommendation.

A lower concentration of an enzyme, methemoglobin reductase, in the pigs' blood makes them more susceptible to sodium nitrite toxicity than other animals.
https://cen.acs.org/articles/92/i41/Counterattacking-Wild-Pig-Invasion-Bacon.html

"Pigs are the most susceptible, then cattle, sheep and then horses." p39

LD50 p43
Adult Human NO3 80-300 mg/kg
Cattle NO3 330-620 mg/kg
Sheep NO3 308 mg/kg
https://www.ars.usda.gov/ARSUserFiles/20801500/NitratePoisoninginRuminantsLecture.pdf
 
Jackblade

Jackblade

Student
Aug 9, 2018
197
@HannibalLector The common point in the cases that you took is that evey person wo took SN has died EVEN with medical treatment attempt.
So taking 20g of Sodium Nitrite with antiemetic and acid reducer and managing to not get found and rescue = death.
Maybe not as quickly and pleasant that it might be, but death.
And every method that stop oxygen to go to the brain has a risk. Even Nembutal
 
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OfficerK

Experienced
May 6, 2018
255
@HannibalLector The common point in the cases that yo took is that evey person wo took SN has died EVEN with medical treatment attempt.
So taking 20g with antiemetic and acid reducer and managing to not get found and rescue= death.

The last subject didn't die. It's possible that he would have without medical attention, though.
 
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Jackblade

Jackblade

Student
Aug 9, 2018
197
Because what if you get found with Nembutal ? You will get rescue, and you may have brain sequels
Those methods are reliable but you need to manage to not get caugh and rescue !
Killing yourself isn't a pleasure party lmao
 
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Jackblade

Jackblade

Student
Aug 9, 2018
197
And I forgot to say but every cases that @HannibalLector took are people that only took SN, not antiemetic and acid reducer with!
Those drugs make SN even more efficient !
 
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Suicideisnirvana

Suicideisnirvana

Specialist
Aug 4, 2018
312
Single cases aren't representative of the entire method at all. Yes, you might survive 40 hours after SA, just as much as your body may naturally overcome the effects of SN for some reason. All the more chemical methods' success depend on how your body reacts to them, and it's a risk you have to take. On the other hand, pleople may pick SN over SA because of it's availability, because we've gathered more information on it, because they knew someone who pulled through this method, which most people on this forum do, or maybe because they don't want to handle a potentially explosive substance that poses danger to other people even after their deaths.
Sadly, the peaceful pill doesn't and may never exist, so every method is bound to fail sometimes, even with the utmost precaution.

Nembutal have 0 failed reported case, 0. So the peaceful pill does exist.
 
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