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neurotoxic

neurotoxic

Experienced
Sep 15, 2019
229
I'm curious about experimenting with alternative routes of administration for sodium nitrite/potassium nitrite. I've only seen a couple posts on here discussing how well SN would work intravenously or rectally, with both suggestions usually resulting in discouragement (which is fair, nobody's done either before possibly for good reason). I'm not a medical professional or anything, but I've also not heard any convincing reasons why one of those two alternatives wouldn't work, so I'm considering trying one or both. Basically the plan is to gather more information, attempt, and document what happens. If anyone has useful information or relevant medical knowledge, It would be very helpful.
 
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adamantc

Student
Mar 29, 2026
160
I'm curious about experimenting with alternative routes of administration for sodium nitrite/potassium nitrite. I've only seen a couple posts on here discussing how well SN would work intravenously or rectally, with both suggestions usually resulting in discouragement (which is fair, nobody's done either before possibly for good reason). I'm not a medical professional or anything, but I've also not heard any convincing reasons why one of those two alternatives wouldn't work, so I'm considering trying one or both. Basically the plan is to gather more information, attempt, and document what happens. If anyone has useful information or relevant medical knowledge, It would be very helpful.
Intravenous wouldn't work for most. Mainly because of how difficult it is to intravenously inject, and the pain you'll feel upon injection. Incorrectly injected, you may face severe pain (and not die), maybe with localised necrosis. Injection of Potassium Chloride (another salt) is only done after the condemned is sedated in execution protocols for this reason.
 
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neurotoxic

neurotoxic

Experienced
Sep 15, 2019
229
Intravenous wouldn't work for most. Mainly because of how difficult it is to intravenously inject, and the pain you'll feel upon injection. Incorrectly injected, you may face severe pain (and not die), maybe with localised necrosis. Injection of Potassium Chloride (another salt) is only done after the condemned is sedated in execution protocols for this reason.
Thats useful info, thank you. I know sodium nitrite IV is used for cyanide poisoning treatment, but i have no idea what would happen with the concentration used for ctb. Since SN isn't my method i do have a backup method in the event of unbearable pain, but ideally i'll be able to tough it out and document.
 
neurotoxic

neurotoxic

Experienced
Sep 15, 2019
229
So to update anyone who might be interested: After doing more research, first I'm going to create mixtures with "safe" dosages of SN (300mg is the maximum given medically from what I can tell) and document the effects of those via intramuscular injection first. This isn't gonna be super in depth but I'll be monitoring my heart rate throughout, and blood pressure/oxygen assuming I'm able to.
 
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overusedusername

overusedusername

stirred crazy
Jul 5, 2026
24
Ooo, I'm curious to read the results.
 
S

Smt9

Member
Jul 1, 2026
6
Please be careful with these types of manipulations. They can have very unpleasant consequences aka purulent abscess -> necrosis -> sepsis/amputation of the limb. Pharmacy saline solution is sterile (autoclaved). Homemade ones.. Well.. you guess... And you can accidentally hit a blood vessel.
 
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EDSsucks

Student
Jul 14, 2026
136
I'm curious about experimenting with alternative routes of administration for sodium nitrite/potassium nitrite. I've only seen a couple posts on here discussing how well SN would work intravenously or rectally, with both suggestions usually resulting in discouragement (which is fair, nobody's done either before possibly for good reason). I'm not a medical professional or anything, but I've also not heard any convincing reasons why one of those two alternatives wouldn't work, so I'm considering trying one or both. Basically the plan is to gather more information, attempt, and document what happens. If anyone has useful information or relevant medical knowledge, It would be very helpful.
As someone with a medical background this sounds like a horribly bad idea.
 
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neurotoxic

neurotoxic

Experienced
Sep 15, 2019
229
As someone with a medical background this sounds like a horribly bad idea.
Mind explaining why its a bad idea? This is why I'm trying it in the first place, I've gotten a lot of "bad idea, wont work" talk but minimal sources or explanation of why it wont work.
We're all here trying to find ways to kill ourselves, keeping that in mind im comfortable with the risks im aware of. It's an experiment.
Please be careful with these types of manipulations. They can have very unpleasant consequences aka purulent abscess -> necrosis -> sepsis/amputation of the limb. Pharmacy saline solution is sterile (autoclaved). Homemade ones.. Well.. you guess... And you can accidentally hit a blood vessel.
Thank you for explaining the risks there, i appreciate the info. I'm not worried about accidentally hitting a blood vessel for the first experiment at least, ive done intramuscular and subcutaneous injections before on myself.
 
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sadbh—itstimetogo🤎

sadbh—itstimetogo🤎

Arcanist
Apr 4, 2026
461
Intravenous wouldn't work for most. Mainly because of how difficult it is to intravenously inject, and the pain you'll feel upon injection. Incorrectly injected, you may face severe pain (and not die), maybe with localised necrosis. Injection of Potassium Chloride (another salt) is only done after the condemned is sedated in execution protocols for this reason.
Same, I wouldn't recommend by IV unless you're already skilled at IV injections.
So to update anyone who might be interested: After doing more research, first I'm going to create mixtures with "safe" dosages of SN (300mg is the maximum given medically from what I can tell) and document the effects of those via intramuscular injection first. This isn't gonna be super in depth but I'll be monitoring my heart rate throughout, and blood pressure/oxygen assuming I'm able to.
Good luck. I wish there were a high tech way to record your vitals and experience. You need a proper lab assistant 😂



I'm definitely curious about SN via boofing. There's no issue with vomiting AND it should be absorbed faster/less conversion to NO. Not sure if it would be painful, or how the dosing might be affected.

If you're gonna experiment on yourself, can you try boofing the smallest amount? 😂 mostly want to know if it's painful (I kind of doubt it though since it's supposed to taste like salt).
 
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neurotoxic

neurotoxic

Experienced
Sep 15, 2019
229
Same, I wouldn't recommend by IV unless you're already skilled at IV injections.

Good luck. I wish there were a high tech way to record your vitals and experience. You need a proper lab assistant 😂



I'm definitely curious about SN via boofing. There's no issue with vomiting AND it should be absorbed faster/less conversion to NO. Not sure if it would be painful, or how the dosing might be affected.

If you're gonna experiment on yourself, can you try boofing the smallest amount? 😂 mostly want to know if it's painful (I kind of doubt it though since it's supposed to taste like salt).
Boofing is on the table! Never thought id say that. I'm planning to test that as well, probably after intramuscular injection with the same small dose. I've heard some people saying it will cause pain due to the salt, but only one way to find out really.
 
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sadbh—itstimetogo🤎

sadbh—itstimetogo🤎

Arcanist
Apr 4, 2026
461
Boofing is on the table! Never thought id say that. I'm planning to test that as well, probably after intramuscular injection with the same small dose. I've heard some people saying it will cause pain due to the salt, but only one way to find out really.
I'm lowkey willing to contribute to this experiment by boofing NaCl 😂
 
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kilowatt

kilowatt

scumfuc
Sep 9, 2023
460
I previously made a thread on sublingual administration if that's something you'd be interested to look into
 
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EDSsucks

Student
Jul 14, 2026
136
Mind explaining why its a bad idea? This is why I'm trying it in the first place, I've gotten a lot of "bad idea, wont work" talk but minimal sources or explanation of why it wont work.
We're all here trying to find ways to kill ourselves, keeping that in mind im comfortable with the risks im aware of. It's an experiment.

Thank you for explaining the risks there, i appreciate the info. I'm not worried about accidentally hitting a blood vessel for the first experiment at least, ive done intramuscular and subcutaneous injections before on myself.
For one thing, as an inorganic salt being used in high concentration, it will have high osmolality in the rectal environment. This is likely to induce diarrhea and GI turbulence, for lack of a better word.
 
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neurotoxic

neurotoxic

Experienced
Sep 15, 2019
229
For one thing, as an inorganic salt being used in high concentration, it will have high osmolality in the rectal environment. This is likely to induce diarrhea and GI turbulence, for lack of a better word.
Fasting would still be part of the protocol for that experiment, a much longer period than for oral administration. I'm expecting discomfort, considering ive survived SN taken orally, but im starting each experiment with a very small dose before i try anything higher. everyone please keep in mind here that an experiment done on suicide methods by someone who is suicidal, will have a lot of room for risk and discomfort. Comfort and safety isnt my concern as much as finding out if it will work at all, and if it will cause vomiting or like @EDSsucks says, GI issues. That being said however, i do need to wait until i am over my current stomach bug before attempting anything that could make it worse.

If it does cause discomfort or other issues, thats also the point of this. the regular SN protocol has a LOT of things in it to mitigate the discomfort when taking it orally, so im expecting to have to come up with a protocol for other routes of administration as well.
 
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sadbh—itstimetogo🤎

sadbh—itstimetogo🤎

Arcanist
Apr 4, 2026
461
Fasting would still be part of the protocol for that experiment, a much longer period than for oral administration. I'm expecting discomfort, considering ive survived SN taken orally, but im starting each experiment with a very small dose before i try anything higher. everyone please keep in mind here that an experiment done on suicide methods by someone who is suicidal, will have a lot of room for risk and discomfort. Comfort and safety isnt my concern as much as finding out if it will work at all, and if it will cause vomiting or like @EDSsucks says, GI issues. That being said however, i do need to wait until i am over my current stomach bug before attempting anything that could make it worse.

If it does cause discomfort or other issues, thats also the point of this. the regular SN protocol has a LOT of things in it to mitigate the discomfort when taking it orally, so im expecting to have to come up with a protocol for other routes of administration as well.
I wonder if you'd consider prepping with laxatives, so there's less to shit out when all the salt gets up there 😭
 
neurotoxic

neurotoxic

Experienced
Sep 15, 2019
229
Will update thread later with documentation, starting the first test
 
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D

DeathSweetDeath

Enlightened
Nov 12, 2025
1,767
So, someone said in their goodbye thread that they tried boofing it last night but they still woke up this morning 🙃. It seems that is not the way, for whatever reason.
 
sadbh—itstimetogo🤎

sadbh—itstimetogo🤎

Arcanist
Apr 4, 2026
461
So, someone said in their goodbye thread that they tried boofing it last night but they still woke up this morning 🙃. It seems that is not the way, for whatever reason.
Can you tag me so I can read it?
 
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neurotoxic

neurotoxic

Experienced
Sep 15, 2019
229
Okay so apologies for the late update. I fell asleep for several hours, probably more because I was sleep deprived than because of the SN. The solution with 300mg sodium nitrite (possibly incorrectly calculated, in hindsight. Somewhere around that.) Basically just caused fast heart rate, and lowered blood oxygen. I do not think my blood pressure machine worked, but im sure it dropped a bit. I feel fine now except for a very sore injection site.
 
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sadbh—itstimetogo🤎

sadbh—itstimetogo🤎

Arcanist
Apr 4, 2026
461
Oh, so you did it by IV and not boofing?
Oh, you did intramuscular IV. I wonder if you'll have a bruise. Did you injected it into your glute?
 

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