Respiratory Depression?

[pelicanportal]

Is respiratory depression a shitty way to go? It sounds peaceful enough if you're asleep when it happens but sounds panic-inducing if you're conscious during it.

Would XR on the benzos fuck it up? I have plenty of XR alprazolam, barely any regular ativan. And how much would work combined with alcohol?

[Vent] It's honestly absurd that less painful methods are completely banned and impossible to obtain. I understand putting some strict barriers up to obtain it, like controlled substances are, but banning it outright is absurd. People shouldn't have to worry about becoming vegetables or traumatizing train drivers to end their own fucking life after a certain age.

 

[hurb]

i do agree with u , that's it's absurd we don't have the right to die, it sounds so logical and yet society outright refuses it

 

[bipolar22]

To induce fatal respiratory depressants you need barbiturates propofol or high strgth opiods. Alcohol just doesnt hit it hard enough benzos much less so. Your best be would be benzodiazepine high dose plus high dose opoids if im not mistaken. Benzos alon3 are very safe and booze even with benzos is less save but not strong enough for what we are trying to achieve

 

[Arvayn]

Respiratory depression is a relatively painless way to die, but painless doesn't mean comfortable. As a matter of fact, for many elderly people, it is considered one of the most fortunate ways to go... Especially if it happens in their sleep.

It'll feel very unpleasant to not be able to breathe, air hunger is one hell of a bitch. You could maybe distract yourself with the pleasant feeling from being inebriated, but it's unlikely to be a perfect solution.

Benzodiazepine overdose is generally a very unreliable method. Alprazolam is fortunately among the stronger benzos (anything above 10mg is already dangerous), but the human body is extremely good at staying alive and expelling foreign substances overtime. Can it kill you? Yes. Will it kill you? Very dubious, and it might have you end up in a worse off situation than not. You'd need to make sure you're not found for a long while. I will reiterate this: This method would have a considerable chance of going very wrong. I do not recommend it.

In a 2004 case study of alprazolam overdose, out of 14 reported attempts, only 5 managed to die, and only 2 of those 5 exclusively used just the benzos.

You wouldn't want to drink too much alcohol. If you get too drunk, that encourages vomiting, which will probably cause you to live; you want to keep the meds down. Drink just enough to get the depressive effects, and no more.

As for how much alprazolam to take, the typical therapeutic doses are between 0.5-10mg, and no more than 30mg should be ingested in a day. Alprazolam has a high bioavailability, and about 80% of the actual dose makes it into the bloodstream. For a ""safer"" (I use this word very loosely here) bet, I'd shoot for at least 1000mg, but do you even have the means to acquire that much?
Side effects of alprazolam OD other than respiratory depression include nightmares and hallucinations, confusion, having an incredibly fast heart rate, extremely low blood tension and drowsiness.

 

[pelicanportal]

Respiratory depression is a relatively painless way to die, but painless doesn't mean comfortable. As a matter of fact, for many elderly people, it is considered one of the most fortunate ways to go... Especially if it happens in their sleep.

It'll feel very unpleasant to not be able to breathe, air hunger is one hell of a bitch. You could maybe distract yourself with the pleasant feeling from being inebriated, but it's unlikely to be a perfect solution.

Benzodiazepine overdose is generally a very unreliable method. Alprazolam is fortunately among the stronger benzos (anything above 10mg is already dangerous), but the human body is extremely good at staying alive and expelling foreign substances overtime. Can it kill you? Yes. Will it kill you? Very dubious, and it might have you end up in a worse off situation than not. You'd need to make sure you're not found for a long while. I will reiterate this: This method would have a considerable chance of going very wrong. I do not recommend it.

In a 2004 case study of alprazolam overdose, out of 14 reported attempts, only 5 managed to die, and only 2 of those 5 exclusively used just the benzos.

You wouldn't want to drink too much alcohol. If you get too drunk, that encourages vomiting, which will probably cause you to live; you want to keep the meds down. Drink just enough to get the depressive effects, and no more.

As for how much alprazolam to take, the typical therapeutic doses are between 0.5-10mg, and no more than 30mg should be ingested in a day. Alprazolam has a high bioavailability, and about 80% of the actual dose makes it into the bloodstream. For a ""safer"" (I use this word very loosely here) bet, I'd shoot for at least 1000mg, but do you even have the means to acquire that much?
Side effects of alprazolam OD other than respiratory depression include nightmares and hallucinations, confusion, having an incredibly fast heart rate, extremely low blood tension and drowsiness.

Thank you very much for this thoughtful information, truly I appreciate it. This is far from my preferred method, but I want to make sure how viable it is or is not before locking in on another one. The others seem too risky, painful, or impossible to obtain.

Would an anti-emetic resolve the vomitting issue?

1000mg is definitely out of reach, I have maybe 80 .5mg XR tablets and I know the extended release factor messes with things.

 

[Arvayn]

You're welcome, I just want to make sure you don't hurt yourself in an avoidable manner and that you have the knowledge to make an informed decision if you decide to go through with it anyway. This method is also very risky, and you'd likely start to panic once the air hunger fully sets in...

Yes, antiemetics would keep you from vomiting, but I recommend that you be very careful about mixing alcohol with antiemetics, because they chemically interact and it often causes extra side effects. The information for this is widely available online in medical journals and articles, so do your research before settling on one.
The antiemetic most commonly recommended on this forum, metoclopramide, causes much more intense sedation and aggravates confusion when taken with alcohol. Do not underestimate the effects of severe confusion; you won't be able to form coherent thoughts, your feelings will be all over the place, you might not be able to remember where you are or what you're doing etc.; this, paired with the panic and hyperventilation, is often what causes people to check themselves in to the hospital.

Plus, 1000mg is simply a ballpark estimate, anyway... Pharmacokinetics are really unpredictable, since each body's chemistry is different. You might need much less or much more than that. You just don't have a way to know. Please do consider the unreliability and low mortality rate of this method if you decide to attempt it.

 

[OzymandiAsh]

Is respiratory depression a shitty way to go? It sounds peaceful enough if you're asleep when it happens but sounds panic-inducing if you're conscious during it.

Would XR on the benzos fuck it up? I have plenty of XR alprazolam, barely any regular ativan. And how much would work combined with alcohol?

[Vent] It's honestly absurd that less painful methods are completely banned and impossible to obtain. I understand putting some strict barriers up to obtain it, like controlled substances are, but banning it outright is absurd. People shouldn't have to worry about becoming vegetables or traumatizing train drivers to end their own fucking life after a certain age.

Good question. I always assumed it was more or less peaceful, but I looked it up and yes, it can be distressing and lead to hypercapnic alarm, air hunger and so on. The best case for CTB is achieving full respiratory arrest quickly.