Questions about Metoclopramide

[Coyote]

Hey. I bought Metoclopramide pills. It is read 10 mg Metoclopramide HCl hydrochloride on it. Now, my question is, it says on it, it is recommended to take one dose (10mg) and wait at least 5 hours to take another. We are supposed to take 3 at the same time right? Wouldn't that cause a problem?

 

[Thegoldenapples]

My packet says the same. Youre doing one stat dose so it won't be a problem. PPH wording recommend it otherwise. I'd do a test with 10mg and see how your stomach reacts. Mine was a little upset so realised it's best to do 48 hour method as I don't think I'd even be able drink N after 30mg.

 

[SweetDreams500]

It could increase the chance of unpleasant side effects.

 

[RedHarlequin]

The maximum advisable dosage of MCP is 30mg/d, doesn't really say how long the pauses between taking it should be. In your case I'd just try it before and see what happens.

 

[camus44]

My packet says the same. Youre doing one stat dose so it won't be a problem. PPH wording recommend it otherwise. I'd do a test with 10mg and see how your stomach reacts. Mine was a little upset so realised it's best to do 48 hour method as I don't think I'd even be able drink N after 30mg.

Hey there - sorry, just to clarify this.

I'm planning on drinking N. I have Metoclopromide, and take 2 x 10mg pills a day, one in the morning and one in the evening.

Should I up the dose before taking N???

Thank you very much. Just trying to get this clear in my head

 

[Thegoldenapples]

Hey there - sorry, just to clarify this.

I'm planning on drinking N. I have Metoclopromide, and take 2 x 10mg pills a day, one in the morning and one in the evening.

Should I up the dose before taking N???

Thank you very much. Just trying to get this clear in my head

You want 30mg at once or 10 mg every 8 hours over 48 hours. As for you already taking it and possibly needing more, @Aap would be able to tell you more. The regime is here https://sanctioned-suicide.net/threads/n-protocol-regime-regimen-notes.27092/

 

[Aap]

The assisted suicide organizations use 30mg an hour before. I'm not sure why anyone feels the need to deviate from that. Loading doses/doses over 48 hours are not need. Thankfully, there is less nonsense about "testing" meto.

Meto will often cause stomach cramps and/or diarrhea due to the fact it is a pro-motility agent. I've written plenty about why testing meto is the worst possible choice if one is concerned about rare side effects from meto and don't need to repeat it here.

 

[Thegoldenapples]

The assisted suicide organizations use 30mg an hour before. I'm not sure why anyone feels the need to deviate from that. Loading doses/doses over 48 hours are not need. Thankfully, there is less nonsense about "testing" meto.

Meto will often cause stomach cramps and/or diarrhea due to the fact it is a pro-motility agent. I've written plenty about why testing meto is the worst possible choice if one is concerned about rare side effects from meto and don't need to repeat it here.

Rare side effects can still happen though and that's the last thing you need on your exit night. Pretty sure the PPH recommends testing prior to make sure it suits your body. I tested it after seeing people on here say it made them so sick they couldn't take it so they had to use a substitute from the PPH. Considering my response to 10mg, if I took 30mg at once, I don't think I'd be able to even take N because my stomach would be too sore.

 

[Aap]

You are completely speaking out of your ass. "Pretty sure" or "I think" when answering a question you have no relevant information to add is the reason shitty information becomes hand wringing becomes endless threads here.

There is a reason both the PPH and assisted suicide organizations recommend a single dose of 30mg of meto 40-60 minutes before. Why should you absolutely positively not test meto if you are concerned about EPS? I'll give you a hint - do some research and find the length of time it takes EPS to develop.

Now, take that answer and compare it to 60 minutes and 48 hours. If you bother to do this rather than make an "I think" or "pretty sure" post, you would realize why the advice to test meto is just bad advice.

 

[Thegoldenapples]

I'm not here to argue with people. I said "pretty sure" because that's what I remember reading. After looking at the PPH again, it states "Note: testing ahead of time for possible side effects is always advised".

I didn't mention EPS. There are a range of side effects that can happen shortly after taking meto, just like any other prescription drug. I experienced that and others on this forum. The 48 hour method is also discussed in the PPH and has been noted on SS numerous times.

I also said "I don't think I'd be able to even take N because my stomach would be too sore" because based on my reaction to 10mg, I'm not willing to try 30mg at once. That was based on my personal experience. I know my limits. Unfortunately, I have a physical illness which doesn't work in my favour at times.

 

[Aap]

If one is concerned about EPS, the single dose method without testing is all that should be utilized. EPS are usually or often irreversible and can develop 24-72 hours after a single dose though more often after repeated doses. EPS are rare, though with the general level of anxiety of most users here, the advice to test meto is the worst advice that could be followed.

 

[checkouttime]

If one is concerned about EPS, the single dose method without testing is all that should be utilized. EPS are usually or often irreversible and can develop 24-72 hours after a single dose though more often after repeated doses. EPS are rare, though with the general level of anxiety of most users here, the advice to test meto is the worst advice that could be followed.

So it takes at least 24hr for the possible side effects to kick in, Hence why so many people choose to take it 40-60mins before the drink SN or N.

so basically the advice in the pph about testing it for possible side effects, is all to do with if people decided to do the 48hr regime. which seems kind of pointless to me if you can totally avoid side effects by taking the stat dose beforehand!!!

Thanks so much for this information by the way, like it when people know what they are talking about. Its calming for the other members who may have concerns!!!!

 

[Anonymous 4]

That puts my kind at rest if I can obtain this AE, as I would just take the stat dose before the N, hoping that the AE don't make me vomit,

The 48hour slow dose is for those who have sensitive stomachs and who would react to a large dose at once, so there are some people I guess who have no choice but to take the 48hour dose,

You are completely speaking out of your ass. "Pretty sure" or "I think" when answering a question you have no relevant information to add is the reason shitty information becomes hand wringing becomes endless threads here.

There is a reason both the PPH and assisted suicide organizations recommend a single dose of 30mg of meto 40-60 minutes before. Why should you absolutely positively not test meto if you are concerned about EPS? I'll give you a hint - do some research and find the length of time it takes EPS to develop.

Now, take that answer and compare it to 60 minutes and 48 hours. If you bother to do this rather than make an "I think" or "pretty sure" post, you would realize why the advice to test meto is just bad advice.

Is there any cases where taking the 30mg meto makes the person sick?? I read that there has been cases where this has happened? Is this did informatuon, or can some people react to 30mg meto leading to vomiting? Which in turn, failed ctb with N?? I'm here for information? Not to argue

 

[Aap]

Meto, in addition to being an antiemetic, speeds the activity of the intestines (called a prokinetic or promotility agent). It won't cause vomiting but can cause diarrhea and a feeling that is like a rumbling stomach.

Those with "weak" stomachs will likely find 2 days of meto much worse than a single dose an hour before.

 

[Thegoldenapples]

Meto, in addition to being an antiemetic, speeds the activity of the intestines (called a prokinetic or promotility agent). It won't cause vomiting but can cause diarrhea and a feeling that is like a rumbling stomach.

Those with "weak" stomachs will likely find 2 days of meto much worse than a single dose an hour before.

Interesting. I'm starting to think I should jsut down 30mg dose then and wish for the best. Maybe repeated doses will make it worse. Ive just followed the PPH so gets confusing. Cheers for the info.

 

[grail]

Have there been many known SN successes without antiemetics?

 

[BaronVon]

I take this medication regularly due to stomach and nausea issues and have never had any side effects

 

[checkouttime]

Meto, in addition to being an antiemetic, speeds the activity of the intestines (called a prokinetic or promotility agent). It won't cause vomiting but can cause diarrhea and a feeling that is like a rumbling stomach.

Those with "weak" stomachs will likely find 2 days of meto much worse than a single dose an hour before.

Seems to me that the 48hr regime is kind of pointless, especially if you can avoidf the 'scary symptoms' that some people with no knowledge have harped on about.

Obviously you have done your research , unlike the people who make the negative claims. you have to question people who make unfounded claims and make false accusations that can be easily proven wrong by people who have actually spent time researching these things. After all we are all told to do our research, that way you don't look like an idiot when your pretending talk about something you clearly don't know about!!!

I'm not saying don't ask questions thats perfectly fine, but if your going to make out that you know about something and think your an expert. It usually helps if you know what your on about and have done your research IMO

 

[Thegoldenapples]

Seems to me that the 48hr regime is kind of pointless, especially if you can avoidf the 'scary symptoms' that some people with no knowledge have harped on about.

Obviously you have done your research , unlike the people who make the negative claims. you have to question people who make unfounded claims and make false accusations that can be easily proven wrong by people who have actually spent time researching these things. After all we are all told to do our research, that way you don't look like an idiot when your pretending talk about something you clearly don't know about!!!

I'm not saying don't ask questions thats perfectly fine, but if your going to make out that you know about something and think your an expert. It usually helps if you know what your on about and have done your research IMO

If the 48 hour is pointless, it wouldn't be in the PPH. It has worked very successfully for some on here with sensitive stomachs. Thats an individual decision that people need to weigh up based on their concerns e.g if it's EPS, then no test and stat dose seems to be the better option.

No one has made themselves out to be an "expert". People start their research from the PPH which was written by experts. PPH says to test prior to and lists some adverse symptoms such as vomiting and more personal experiences can be found online. You can't invalidate those potential side effects. Then it lists alternatives if meto isn't suitable because sometime it's not. If you think the PPH gives people no knowledge then I suggest you talk to Dr N about that. Some members have also gone to a lot of trouble to discuss it like in this thread I posted above to help educate people https://sanctioned-suicide.net/threads/n-protocol-regime-regimen-notes.27092/

We come here to find a method to cbt and figure out what's best by asking questions, looking through threads, looking online and hearing others experiences. My adverse symptoms came on within 30mins, not after one hour. Meto works within the hour and some symptoms can come on within that time frame. I know someone who took 30mg, didn't test, and couldn't go through with it because he said his stomach was too sore. He couldn't move so had to move to the 48 hour regime weeks later and successfuly cbt. Hence why I tested and my concern given my reaction to 10mg but another friend did 30mg and didn't notice a thing. Felt no different.

Everyone is different and their own individual experiences after testing and following the PPH advice are not discounted because they are not an "expert". It's a decision that every individual person needs to weigh up considering their own needs, concerns and their reactions based on past use of prescriptions and after proper research with what they feel comfortable with.

 

[checkouttime]

Might i just point out at no point did i quote or say i was saying anything to do with what you said. i was agreeing with what another member had posted and thanking them for researching and providing facts..........some people may see that as suspicious????? Funny that you thought i was talking about you?

Also never said DON"T do the 48hr regime, but that i thought it realistically pointless IMO . Thats my opinion, no1 else has to agree., its upto them. just follow the evidence and decide what they want


I know what things posted i trust and believe , thats my CHOICE, just like it is for many others. I'll let other members decide who they want to listen too. I'm sure they will make the right choice, people on here may be ill but stupid they aren't.

 

[Thegoldenapples]

Yes and after thanking him you went to say that people with no knowledge harp on about "scary symptoms" but they have read the PPH, other sources and experienced it themselves. That's why some people decide to switch to alternatives/regimes.

I didn't say you said "don't" and I never thought you were talking about me, I merely commented on various comments you made that I don't agree with E.g 48 regime was pointless, I said it wasn't pointless for certain circumstances and listed reasons. You also think you can "avoid" the adverse effects which you can't always, even with stat dose. Things like EPS seem to be different and given the delay in reaction, then best not to test if that is someone's concern but there are other adverse effects that come on within the hour.

PPH discussed some side effects for a reason which is why they advised to test. Whether people test or not is up to them, it's depends on what they are concerned about. You think everything is "suspicious" these days. I'm not surprised you read into my post that way.

 

[upthedownescalatorr]

Planning to take 10mg diazepam half an hour before 30mg meto then N an hour later. Mainly just to keep me calm but just wondering if there would still be any benefit to having dph on hand to counteract any eps symptoms as is often recommended. I've heard diazepam can be effective for this anyway and at the same time I'm a little concerned that taking dph on top will send me to sleep before I can take N.

 

[checkouttime]

Planning to take 10mg diazepam half an hour before 30mg meto then N an hour later. Mainly just to keep me calm but just wondering if there would still be any benefit to having dph on hand to counteract any eps symptoms as is often recommended. I've heard diazepam can be effective for this anyway and at the same time I'm a little concerned that taking dph on top will send me to sleep before I can take N.

EPS doesn't happen when taking a stat dose, so its easily avoidable if one wants to. see below post

If one is concerned about EPS, the single dose method without testing is all that should be utilized. EPS are usually or often irreversible and can develop 24-72 hours after a single dose though more often after repeated doses. EPS are rare, though with the general level of anxiety of most users here, the advice to test meto is the worst advice that could be followed.

 

[Foolish King]

I'll add my two cents to that discussion above on meto usage, although obviously this is just my own personal experience over the last few days or could even possibly be from something else so keep that in mind.

I started taking 10mg every 12 hours about a day and a half ago and a few hours after the first dose I started feeling pretty nauseous and weak. I skipped a dose last night but I still woke up this morning with difficulty getting out of bed and kinda tingly feelings in my hands and feet. It isn't the end of the world or anything but with my stomach feeling the way it does now I'm not sure I should drink the SN I have, and the weakness prevented me from getting some of my final errands done so I think I'll push back the date a day.

Hypothetically if I had just taken 30mg an hour before hand I'm not sure if I would have avoided any side effects all together since they took a few hours to manifest or if they would have come fast enough and strong enough to screw me over because of the higher dosage. Either way even though I'm not feeling great I don't think it was all bad to test and consider that second possiblity.

[edit]: I guess I meant it isn't all bad for someone like me who has a bit of extra time on their hands if they need it, someone in a big hurry might not have the luxury I do though so it could be worse for them.

 

[checkouttime]

I would imagine taking the stat dose is the best way to use this stuff. that way the side effects if any will be minimal. i mean when you take a drug the side effects happen after the drug starts to work. we are told to take the drug a certain amount of time before hand as thats how long it takes for the drug to work. after taking either SN or N your are unconscious very fast after ingesting it. I mean there's actually 6 different drugs to chose from (i think there are actually more aswell if you search or read the pph)




or then plenty of members ave had success while not using an anti e. vomitting while taking SN has never been reported as a failure.