Propranolol dosage for SN

[Jumper Geo]

There is a lot of information to consider taking Propranolol the PPeH recommend 800mg of Propranolol mixed with SN but I still question the quantity, it has been reduced twice from 2g to 1g and now 800mg and the only benefits I can find are the two listed below, 800mg is not an overdose, I am counting on the SN to CTB not the Propranolol. A 27-year old female weighing 60kg presents to ED approximately one hour after swallowing 70 x 40mg Propranolol tablets (= 2.8 grams) with suicidal intent. At the time of assessment she is drowsy (GCS 13) with a heart rate of 46 bpm and BP 100/60. Fifteen minutes earlier she had been awake and able to give a history to paramedics. ECG shows sinus bradycardia of 45 bpm with PR interval 210ms, QRS duration 115ms, QT interval 380ms and a small R wave in aVR of approximately 2mm in height, so it might just be beneficial to take another lower 40mg of Propranolol mixed with the SN as a lower dose means a lower chance of vomiting.

1, It prevents tachycardia, the heart racing and beating fast.
2, When the brain receives a message there is insufficient oxygen, a message is sent to the heart to increase blood flow which is blocked

Propanolol Overdose

aka Toxicology Conundrum 044 A 27-year old female weighing 60kg presents to ED approximately one hour after swallowing 70 x 40mg propranolol tablets (= 2.8 grams) with suicidal intent. At the time of assessment she is drowsy (GCS 13) with a heart rate of 46 bpm and BP 100/60. Fifteen minutes...

litfl.com

I dissolved one 40mg tablet in chilled water to make sure it was immediate release, it took 10 minutes to dissolve and I kept stirring it, the lower dosages are immediate release and the 80mg capsules are slow release but you will see SR on the box for slow release.

Antacids with aluminum hydroxide make Propranolol less effective, aluminum hydroxide antacids are usually sold OTC.
Taking Cimetidine increases the levels of Propranolol in the blood
Taking Ibuprofen may decrease the blood pressure-lowering effects of Propranolol .
Taking a lower dose is more effective than taking a high dose.

All the information is linked below, there are lot's more interactions not recommended with Propranolol but don't apply to me so it's best to read them yourself.

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.108.846501

Propranolol: Side Effects, Dosage, Uses, and More

Propranolol is used to treat high blood pressure, atrial fibrillation, tremor, and other conditions. Learn about side effects, warnings, dosage, and more.

www.healthline.com

This is my current regime one thing I'm sure of I will be taking two lower doses of Propranolol at 20.00 and 22.15 but I'm unsure of my final dose to mix with the SN

08:00hrs 01 X 10mg Metoclopramide
11:00hrs 02 X Big Macs and Fries with Vanilla Milkshake
15:00hrs 02 X KFC Chicken Burgers, Chips and Coke
16:00hrs 01 X 10mg Metoclopramide
16:00hrs 01 X Begin 8 Hour FAST
20:00hrs 01 X 40mg Propranolol (40mg)
22.00hrs 01 X Begin 2 Hour Water FAST
22:15hrs 01 X 40mg Propranolol (40mg)
22:30hrs 04 X 75mg Ranitidine (300mg)
22:45hrs 03 X 10mg Metoclopramide (30mg)
23:00hrs 02 X 500mg of Paracetamol (1,000mg)
23:15hrs 01 X 10mg Diazepam (10mg)
23:50hrs 01 X Last roll up of Golden Virginia tobacco
24:00hrs (?) X 40mg Propranolol (?)
24:00hrs 01 X 30g SN (30,000mg)

Propranolol Overdoses

Why Propranolol? – AntiDepAware

antidepaware.co.uk

300mg Ranitidine versus 800mg Cimetidine

[Effect of 300 mg of ranitidine, 800 mg of cimetidine and a placebo administered after the evening meal on 24-hour gastric pH in patients with duodenal ulcer] - PubMed

Twenty-four-hour intragastric pH monitoring was performed in 20 patients with duodenal ulcer in order to compare the results obtained with placebo, ranitidine 300 mg and cimetidine 800 mg administered one hour (7 PM) after evening meal (6 PM). During each 24 h period (8 AM-8 AM), gastric pH was...

pubmed.ncbi.nlm.nih.gov

Cheers

Geo

 

[aminend]

I've same question
When do u want to do ctb

 

[Jumper Geo]

This is an old video of Philip Nitschke mixing SN and Propranolol and there are newer versions of the information below as the PPeH now recommend 800mg Propranolol to mix with the SN, so it would be nice seeing an updated copy of the PPeH. Well I hope this information can be found with an easy search.

 

[SSlostallhope]

Thanks for the info geo. Wish I could join ya on that kfc

 

[Brokenwithbpd]

you will be missed

 

[Jumper Geo]

you will be missed

Not ready to CTB just yet still in the planning stage I thought I would create a thread as I have been giving information on different threads but if someone searched Protanolol it wouldn't come up so at least this information will show up in a search.

Thanks

Cheers

Geo

 

[SSlostallhope]

Took 20mg at midnight last night. Took 15 mins to start lowering my heart rate. Mine usually sits at 106bpm took a few hours to get it down to 69bpm . Will try 30 tonight

 

[aminend]

This is an old video of Philip Nitschke mixing SN and Propranolol and there are newer versions of the information below as the PPeH now recommend 800mg Propranolol to mix with the SN, so it would be nice seeing an updated copy of the PPeH. Well I hope this information can be found with an easy search.



View attachment 39011
View attachment 39012

Very useful movie

 

[pleasethistime]

Do we have to mix it with sn water?
Can we just take them before?
2 grams is a lot.

 

[Brokenwithbpd]

How are you doing?

 

[Living sucks]

Do we have to mix it with sn water?
Can we just take them before?
2 grams is a lot.

It is no longer 2g.. it's 800mg. That was the whole point of this thread .. to discuss the lowered dosage ..
@sleepless

 

[Jumper Geo]

Thanks to @Living sucks for this updated PPeH page. I am currently experimenting with 40mg of Propanolol all our bodies are different and we all react differently to drugs so best to do your own research, I am changing my schedule to take 200mg, 5 pills at 23.00 as I have been doing readings for 4 hours, I started at 13.00 with a Heartbeat reading of 93-83 and the best readings I have are 13.10, 14,00 and 15.30 my last reading was at 16.00 and was 93-79.

Tomorrow I will take 120mg to see how long it takes to enter my system and start working and then I will make my decision if I will take 800mg or 200mg.

08:00hrs 01 X 10mg Metoclopramide
11:00hrs 02 X Big Macs and Fries with Vanilla Milkshake
15:00hrs 02 X KFC Chicken Burgers, Chips and Coke
16:00hrs 01 X 10mg Metoclopramide
16:00hrs 01 X Begin 8 Hour FAST
22.00hrs 01 X Begin 2 Hour Water FAST
23:00hrs 04 X 75mg Ranitidine (300mg)
23:00hrs 05 X 40mg Propranolol (200mg)
23:00hrs 03 X 10mg Metoclopramide (30mg)
23:00hrs 02 X 500mg of Paracetamol (1,000mg)
23:15hrs 01 X 10mg Diazepam (10mg)
23:50hrs 01 X Last roll up of Golden Virginia tobacco
24:00hrs (?) X 40mg Propranolol (200mg) or (800mg)
24:00hrs 01 X 30g SN (30,000mg)

Cheers

Geo

 

[bluesky1972-2019]

I have SN, Antiemetics, Antacid and the Dr has recently prescribed Propranolol (40mg tablets)
So is it ok to mix 800mg Propranolol with 30g SN. Would this method improve the speed of unconsciousness?

 

[Jumper Geo]

I have SN, Antiemetics, Antacid and the Dr has recently prescribed Propranolol (40mg tablets)
So is it ok to mix 800mg Propranolol with 30g SN. Would this method improve the speed of unconsciousness?

I have only seen a few reports but it does seem people lose consciousness faster when using propanolol, below is a goodbye thread where they stopped communicating in minutes.

https://sanctioned-suicide.net/threads/my-final-day-has-come.43488/

Cheers

Geo

 

[bluesky1972-2019]

I have only seen a few reports but it does seem people lose consciousness faster when using propanolol, below is a goodbye thread where they stopped communicating in minutes.

https://sanctioned-suicide.net/threads/my-final-day-has-come.43488/

Cheers

Geo

Yes seems like within 5 minutes the effects took over and no further messages. I do hope he found the peace he was looking for. I have 840mg Propranolol, SN, Primperan and Tagamet. So hopefully everything I need is in place.

 

[Jumper Geo]

Yes seems like within 5 minutes the effects took over and no further messages. I do hope he found the peace he was looking for. I have 840mg Propranolol, SN, Primperan and Tagamet. So hopefully everything I need is in place.

Sounds like you have your bus ticket already and waiting for the bus.

Cheers

Geo

 

[bluesky1972-2019]

Sounds like you have your bus ticket already and waiting for the bus.

Cheers

Geo

Yes, it's just a matter of when. It does bring me comfort knowing I can CTB when I'm ready.

 

[Jumper Geo]

Well after researching and experimenting with Propanolol I am finally happy with my SN regime, please see link below. What is the lethal dose of propranolol? Any ingested dose of propranolol > 1 g is considered to be potentially lethal, but there are cases of people ingesting 2,8 grams and surviving but add SN and it's .

https://sanctioned-suicide.net/thre...les-on-page-1-before-posting.1253/post-795460

Cheers

Geo

 

[suicidebabyseal]

Hi Geo

Thanks for sharing your regimen. I was having doubts about when was one supposed to take the propranolol and in which proportion. It is really helpful.

 

[Jumper Geo]

Serial Killer Geo,

I have reduced the amount of pills in my regime so I can get it down to a minimum amount and reduce the chances of me vomiting, I have been hitting my head against the wall for ages as the PPeH said to mix 2g then 1g then 800mg with the SN and I studied these meds and it takes a minimum 30 minutes to start working so your not going to get the full benefits, I even done my own testing above, I thought it was strange but after reading the PPeH again and again I somehow thought it would help with the absorption of SN but as this goodbye thread has proved Protonanolol did not help but he may have vomited it all up.

https://sanctioned-suicide.net/threads/the-documenting-of-all_pointless-passing-away-by-sn.44504/

The PPeH has recorded times of 3 and 12 minutes to lose consciousness but they don't display the regime they followed so that's bad taste, lucky we also have Faust who documented his SN experience and he done a predose of 80mg and he was unconscious in minutes.

https://sanctioned-suicide.net/threads/my-final-day-has-come.43488/

I am fairly confident if I take a dose of 200mg 60 minutes before dissolved in water and take another 200mg dissolved with the SN it will be the best method for me and I should lose consciousness quickly, I will dissolve all the meds in a little bit of water for fast action.

1, It prevents tachycardia, the heart racing and beating fast.
2, When the brain receives a message there is insufficient oxygen, a message is sent to the heart to increase blood flow which is blocked.
3, Reduces your heart rate and has a calming effect,

Updated regime

11:00hrs 02 X Big Macs and Fries with Vanilla Milkshake
15:00hrs 02 X KFC Chicken Burgers, Chips and Coke
16:00hrs 01 X Begin 8 Hour FAST
22.00hrs 01 X Begin 2 Hour Water FAST
22:45hrs 03 X 10mg Metoclopramide (30mg)
23:45hrs 04 X 75mg Ranitidine (300mg)
23:00hrs 05 X 40mg Propranolol (200mg)
23:00hrs 02 X 500mg of Paracetamol (1,000mg)
23:50hrs 01 X Last roll up of Golden Virginia tobacco
24:00hrs 05 X 40mg Propranolol (200mg)
24:00hrs 01 X 30grams SN (30,000mg)
24:00hrs 01 X Swallow SN and Propranolol in 50/100ml Water, Rizla Bomb or Yum Yum Chocolate Bomb (Not Decided Yet
01.00hrs 01 X CBT Woohoo

Cheers

Geo

Pro Lifer Geo.

I would just like to mention I have been suffering from the side effects from Risperidone for nearly two years I have told my medical coordinator my side effects and he never explained sod all to me just kept saying it's depression and for over a year kept saying we have to find the right AD to give you, I have no energy and motivation, low sex drive can't even be bothered to wash or clean my teeth, had to give up my job I get out of bed lay on the settee and watch TV and surf the internet and drink copious amounts of tea, well I am British you know, but I feel the same mentally as I was before going on risperidone so I have been reading about what the effects are and it seems everything seems to be tied into the D2 receptor which produces and releases dopamine the neurotransmitter where all your pleasure in life comes from if the flow is interrupted you suffer from lack of energy and motivation and sexual performance there is a very long list of side effects.

Like everything this comes with WARNINGS producing to much dopamines leads to some serious side effects and addictions, can cause psychosis and you can develop OCD tendencies and sexual addiction, gambling addictions and so on, best to discuss with your doctor or search the internet and research the Good and Bad effects of dopamine I will put a couple of links below so please read them very carefully.

After my finding I decided to go with a natural solution multi vitamins I had two types I bought for my mother a while ago and this was part of what I wanted to order so I have highlighted them below what I have been taking for a couple of days and the effects I am feeling today.

I have ordered multi vitamins to see if my symptoms improve, I don't know if its the placebo effect but I am feeling better I have had a shave and brushed my teeth and just got out of the bath, which I really struggled to do, I am only taking the highlighted vitamins below so far but if the other ones are good I will let you know, I won't take any additional vitamins if the effects from these two are good and last.

Turmeric 95% Curcumin, tested on mice and was shown to increase dopamine but no human trials as of yet.
Vitamin D D3 50UG, 2000 IU
Pure 1000mg Pure Cod Liver Oil
L-Tyrosine, Capsule 500mg is a good for producing dopamines, google the benefits
Very strong Probiotic 50 Billion CFU Bio Cultures with Prebiotics
Red Korean Ginseng minimum strength, 8000mg daily

If all these fail there is a drug used for Parkinson disease called Selegiline on prescription but I read for the USA it may not be covered by insurance if you haven't got Parkinson disease and may need to pay for it yourself but please be aware of to much dopamine it causes some serious side effect. if you are producing to much dopamine you may need, MAO-B which is an enzyme that hangs around the membranes of your mitochondria (your cells' battery packs) in the brain. MAO-B eats up neurotransmitters, including dopamine.

How Selegiline Protects Your Brain and Keeps You Young

Everyone is looking for that magic pill to make you run faster, jump higher, think faster, and live longer. That may not exist for now, but there’s one prescription drug that people swear by to increase lifespan and brain functioning, even though it’s minimally researched and not widely...

blog.daveasprey.com

Dopamine agonists (pramipexole, ropinirole)

Dopamine agonists is the name used to describe a type (class) of Parkinson’s drug. You will be prescribed an unbranded dopamine agonist medication such as ropinirole, or a branded dopamine agonist such as Mirapexin.

www.parkinsons.org.uk

Honestly it could be a placebo effect but this is the best I have been in about 2 years, I have managed to wash and clean myself, done a few choirs around the house it feels like a fog has lifted and I seem to have regained some energy and motivation I actually felt rather happy sitting here watching TV and I haven't had that feeling in a long time.

I am actually sitting here thinking of things I can do I feel really good I've not even had a stella artois, lol anyway before you rush out or buy any vitamins lets give it a week or two to see if my unmotivated self returns like I said it could just be a placebo effect and I turn back into a zombie. Please GOD I hope it doesn't.

But I thought I would share this good news with you even if it does turn out to be temporary but I am even thinking of cycling again as I must have put on over 2 stone sat at home doing nothing, eating junk food.

My next step is trying to go to sleep at a normal time and get up early and see if I can get a routine going.

My old girlfriend used to say I send mixed messages, I suppose she could have been right as on the first message I am helping you to kill yourself and the second message trying to save you, .

Anyway I will end it here and I will give an update in a month to see if my life has changed, that's if I'm not banned for being a pro lifer, but this was all down to SS as I started to read and send messages and something in my brain switched on as I couldn't be bothered to do anything.

Thanks everyone I still might need my SN regime, haha. Just remember to read and research anything yourself any member suggests, this way you are aware of any dangerous side effects and it's easy to find with a simple google search.

Cheers

Geo

 

[Busdriver]

Nice regimen!

You are leaving SS for a month or maybe longer?

Perhaps the vitamins could help to recover from being suicidal. You deserve a happy, good life.

I am going to miss you, buddy

 

[Jumper Geo]

Nice regimen!

You are leaving SS for a month or maybe longer?

Perhaps the vitamins could help to recover from being suicidal. You deserve a happy, good life.

I am going to miss you, buddy

No still here I just want to see if it's permanent my plans haven't changed yet, lol it could be a placebo effect I may wake up tomorrow and feel like crap I will try and get an early night that will be hard as I enjoy staying up until about 4am and waking up around noon.

Nothing has changed yet, even if I am OK I am still pro choice and maybe I will start lobbying the bloody UK Government to give people the right to die when they choose, like I've always said we don't get a choice coming into this world we should have a choice when and how we leave it.

Cheers Man.

Geo

 

[Busdriver]

I hope you do feel better and eventually leave this place. It is always better to be a pro-lifer than to be suicidal.

It is hard to 'forget' about suicidal thoughts and mindset. Lol, would be amazing if you can make euthanasia easy to be accessed.

 

[Zappfe lover]

No still here I just want to see if it's permanent my plans haven't changed yet, lol it could be a placebo effect I may wake up tomorrow and feel like crap I will try and get an early night that will be hard as I enjoy staying up until about 4am and waking up around noon.

Nothing has changed yet, even if I am OK I am still pro choice and maybe I will start lobbying the bloody UK Government to give people the right to die when they choose, like I've always said we don't get a choice coming into this world we should have a choice when and how we leave it.

Cheers Man.

Geo

Hope you keep on getting better (:

 

[Jumper Geo]

I hope you do feel better and eventually leave this place. It is always better to be a pro-lifer than to be suicidal.

It is hard to 'forget' about suicidal thoughts and mindset. Lol, would be amazing if you can make euthanasia easy to be accessed.

You don't want me to leave, lol I won't mention what he say's to me in our PM's to horrifiy and shock me, lol. I think I have gone as far as I can with SN and meds to try and make it as peaceful and painless as possible I wish I could actually video myself so we would have proof it is a painless way to CTB.

Cheers

Geo

 

[sarahlouise]

Very interesting reading, I hope you continue to feel better. Can I ask if you are still taking risperidone?
I'm taking quietipine but at a lower dose now, I would stop taking it altogether but I can't sleep without it. I hate the side effects.

 

[Jumper Geo]

Very interesting reading, I hope you continue to feel better. Can I ask if you are still taking risperidone?
I'm taking quietipine but at a lower dose now, I would stop taking it altogether but I can't sleep without it. I hate the side effects.

Sorry to hear that I stopped over a year ago, the bloody doctors would have had me on them for life but I stopped without telling them I was on 2mg and dropped to 1mg but after a couple of weeks stopped I was worried and ready to restart risperidone again in case I heard any voices but I new the voices were created by my own brain so I wouldn't do anything stupid and just ignored them, I did get a slight case of Tinnitus fortunately it's not to loud and it's not constant but I get it every day, comes and goes.

Only a suggestion why not research what aides sleep and what foods or vitamin supplement will increase your chances of getting a good nights sleep, I have given you this link so try eating more of the foods that help or find a supplement, feels like I'm turning into a health guru, lol I will be really pissed if I'm back to square one tomorrow.

10 Ways to Increase Melatonin Naturally for Better Sleep

From tryptophan, sun, and superfoods to blocking blue light, and minimizing caffeine and EMF, we have your covered for connecting to circadian rhythms.

lifespa.com

Cheers

Geo

 

[Lorntroubles]

Hey @Jumper Geo, how did you feel after testing 200mg Propranolol? It's a bit much...

 

[Jumper Geo]

Hey @Jumper Geo, how did you feel after testing 200mg Propranolol? It's a bit much...

I explained my plan in message #12, I did feel calm and relaxed but I am a smoker and I did struggle at times with my breathing, I laid down as I was tired and I struggled I was wheezing quite loud my chest was tight and I had a coughing fit and dizzy spell so I know the pills worked, I went out and sat in the fresh air and it was better. I started to feel better after 7 hours I was still very calm but my breathing was fine and I laid down for a bit. I am confident I can add 80mg and last 1 hour.

But there was a good question on the other thread that I missed.

https://sanctioned-suicide.net/thre...ointless-passing-away-by-sn.44504/post-810662

Cheers

Geo

 

[sarahlouise]

Sorry to hear that I stopped over a year ago, the bloody doctors would have had me on them for life but I stopped without telling them I was on 2mg and dropped to 1mg but after a couple of weeks stopped I was worried and ready to restart risperidone again in case I heard any voices but I new the voices were created by my own brain so I wouldn't do anything stupid and just ignored them, I did get a slight case of Tinnitus fortunately it's not to loud and it's not constant but I get it every day, comes and goes.

Only a suggestion why not research what aides sleep and what foods or vitamin supplement will increase your chances of getting a good nights sleep, I have given you this link so try eating more of the foods that help or find a supplement, feels like I'm turning into a health guru, lol I will be really pissed if I'm back to square one tomorrow.

10 Ways to Increase Melatonin Naturally for Better Sleep

From tryptophan, sun, and superfoods to blocking blue light, and minimizing caffeine and EMF, we have your covered for connecting to circadian rhythms.

lifespa.com

Cheers

Geo

Thank you so much for you help and advice, it's much appreciated :-)