Method Gothbird's SN Protocol

[gothbird]

I don't know your location, but there are online international pharmacies you can use to reliably source antiemetics. The payment is kinda funky (can't use credit cards due to the pharmacies existing in a gray area), but they are reliable and ship real products.

Can't get hard stuff like benzos, but meto, propranolol, digoxin are all available. Many will claim you need a prescription but will still ship without a prescription.

Trans people who have to diy their meds use these sites regularly. You can research all this on Reddit with some digging if you're interested. Typically any sub that requires an expensive or hard to get medication (like tretinoin) is a also a good place to look

This is SUPER helpful. Thank you. I'll do some digging!

 

[gothbird]

Already locked it down. Thank you SO much @quietwoods Looks like the protocol will be changing if they arrive!

 

[sydel sushi]

I'm using omeprazole mostly because I can't get antiemetics. Just to be clear though, it's not a replacement for an antiemetic. It's a PPI, meaning it reduces stomach acid over time. So, yeah. It's not going to stop my nausea or prevent vomiting, but it can help keep the stomach environment less hostile, especially because I'll have fasted.

You can take it the day of without a loading period because it still reduces acid secretion after one dose, but it's more effective if you take it consistently for a few days. That said, in a pinch, one dose is better than none.

Because I have nothing else, omeprazole + fasting + cold water + no gag reflex is about as stable a setup as I'm going to get regarding vomit prevention haha.

I see. I am able to source domperidone (maybe even meto, but i am a bit worried abt the side effects), but I also have a history of acid reflux so I'm considering taking some sort of antacid to maybe prevent the Super Nausea™ that might happen. Thank you for answering!

 

[gothbird]

I see. I am able to source domperidone (maybe even meto, but i am a bit worried abt the side effects), but I also have a history of acid reflux so I'm considering taking some sort of antacid to maybe prevent the Super Nausea™ that might happen. Thank you for answering!

If you can get domperidone, that's a solid choice. It doesn't cross the blood brain barrier, so it avoids the neurological side effects that meto sometimes causes (like restlessness or extrapyramidal symptoms). Most people tolerate it well at 10–20ish mg, taken about 30 to 60 minutes before.

Antacids can help with acid reflux, but be cautious with which kind you take. Avoid anything with high sodium bicarbonate content right before SN because it can interfere with stomach acidity and slow absorption. If you're using something like famotidine (pepcid I think it's called to most people?) or omeprazole, those are fine to take in the days leading up to ease your baseline reflux, but avoid taking them right before the SN dose. (I also have acid reflux issues haha)

Domperidone + fasting + cold water mix = best chance of avoiding vomiting. Don't overdo fluids after dosing and sip if needed, but no chugging.

Hope that helps!

 

[Romanticize]

Hello. I didnt read all the answers (just the OP) and overall the plan is very good and well thought but I have some remarks:
1) biggest downside is no meto, but ondansetron is viable replacement. Ondansetron doesnt work that long, why take it so early and many doses?
2) No fasting?! Big minus.
3) You have Oxy and Zopiclone. I would take more oxy and more zopiclone (especially zopiclone). Oxy i dont know your tolerance and if you vomit after opioids, but 5mg is tiny tiny dose, almost sub perceptible. I would go for at least 20-40mg oxy and 20-30mg+ zopiclone.
4) I would drop ibuprofen or paracetamol completely. Neither paracetamol nor ibuprofen is effective against the pain or toxicity caused by SN overdose.
The symptoms arise from hypoxia and chemical damage, not from inflammation or prostaglandins, which these drugs target.