Discussion Pain-relieving or sedative?

[Freedomm]

The SN instructions say that if you are taking a painkiller, you should avoid the sedative to reduce the risk of vomiting. I can't decide which is better, I am confused by the stomach irritation from ibuprofen, which will most likely also contribute to vomiting. Paracetamol is quite toxic to the liver, given the hypoxia, I am afraid that this could lead to liver damage if I somehow survive. So I would rather choose a sedative. I would like to hear your opinions guys.