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Richard Langford

Enlightened
Jan 10, 2025
1,019
If these are crushed in a pill crusher what would be a fatal dose? They could also be combined with valium.

Obviously tolerance comes into it. I have zero.
 
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supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
definitely not. in my younger years my dealer used to get these, and, while usually i'd get fucked up and puke a lot, i don't think i ever even got to the point of fully blacking out; just heavy nods.

i'm unable to find any data on the ld50 in humans (which is common, for most drugs), so th nearest supposition would be that of lab mice, which is between 320-426 mg/kg. (i.e. if you weighed 100kg (and also were a lab mouse) the dose that would be fatal in 50% of the subjects tested with said dose would be anywhere from 32,000-42,600mg)
this is why single drug lethality is usually so extremely low, because yeah, basically ALL ld50s are fucking ridiculous

usually mice ld50 are the most similar to humans, of any possible other creature type, though it's impossible to tell how much or which direction that lethal dose would shift. i will note that in studies that included BOTH mice and human ld50s, ive never seen a result vary >20% tho
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
definitely not. in my younger years my dealer used to get these, and, while usually i'd get fucked up and puke a lot, i don't think i ever even got to the point of fully blacking out; just heavy nods.

i'm unable to find any data on the ld50 in humans (which is common, for most drugs), so th nearest supposition would be that of lab mice, which is between 320-426 mg/kg. (i.e. if you weighed 100kg (and also were a lab mouse) the dose that would be fatal in 50% of the subjects tested with said dose would be anywhere from 32,000-42,600mg)
this is why single drug lethality is usually so extremely low, because yeah, basically ALL ld50s are fucking ridiculous

usually mice ld50 are the most similar to humans, of any possible other creature type, though it's impossible to tell how much or which direction that lethal dose would shift. i will note that in studies that included BOTH mice and human ld50s, ive never seen a result vary >20% tho
That is as you suggest is wholeheartedly silly - 32,000 - 42,600mg. I was 'hoping' for a more real world figure (not a criticism of you by the way). Case in point 80mg of Oxycodone is apparently likely to cause "severe respiratory depression" . One would think 700mg of crushed oxycontin would do far worse? Or wouldn't it?

Edit. As you say Morphine Nausea then comes into it.
 
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supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
while somewhat true (and while i can't find a link to the study to determine if the ld50 was all cause or acute toxicity alone, so there's defs merit in your doubt), you'd be amazed at the abhorrent conditions one can be subjected to, and somehow survive (most often with severe lasting/permanent damage, bu survive nonetheless).
there is a chance, yes, that 700mg of oxy could kill you, i'd honestly wager a guess that death would be be rare from that dose alone (unless further conditions came to play, i.e. fall face down and become asphyxiated by a blanket or pillow, choking on emesis, or some prior existing medical condition potentiated by the drugs effect)

unfortunately, the reason most of us on here (myself included, and especially myself lol) are so resolute on drug combos and ridiculous dosages, is because a lot of us have tried and failed with what seemed impossible to have survived (and i mean that in the most earnest sense)
for example, my last major, planned attempt, i took 9000mg of temazepam (bioequivelent to about 300mg xanax) in conjunction with smoking 3 blues (while at or near the peak blood plasma concetrate of the temazapam), plus 1mg ativan, just because i had it onhand, and it wasn't enough. i got rescued, and the story continues.
believe me when i tell you that it's genuinely not worth it to push your luck with minimum possible dosages, this world is cruel and fucked up, and the odds are stacked against you in this case.
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
while somewhat true (and while i can't find a link to the study to determine if the ld50 was all cause or acute toxicity alone, so there's defs merit in your doubt), you'd be amazed at the abhorrent conditions one can be subjected to, and somehow survive (most often with severe lasting/permanent damage, bu survive nonetheless).
there is a chance, yes, that 700mg of oxy could kill you, i'd honestly wager a guess that death would be be rare from that dose alone (unless further conditions came to play, i.e. fall face down and become asphyxiated by a blanket or pillow, choking on emesis, or some prior existing medical condition potentiated by the drugs effect)

unfortunately, the reason most of us on here (myself included, and especially myself lol) are so resolute on drug combos and ridiculous dosages, is because a lot of us have tried and failed with what seemed impossible to have survived (and i mean that in the most earnest sense)
for example, my last major, planned attempt, i took 9000mg of temazepam (bioequivelent to about 300mg xanax) in conjunction with smoking 3 blues (while at or near the peak blood plasma concetrate of the temazapam), plus 1mg ativan, just because i had it onhand, and it wasn't enough. i got rescued, and the story continues.
believe me when i tell you that it's genuinely not worth it to push your luck with minimum possible dosages, this world is cruel and fucked up, and the odds are stacked against you in this case.
You sound like you possibly have a little bit of tolerance to various things though that's impacting your particular situation? Or whatever was in the Blues wasn't what you thought?

Notwithstanding that, I don't want to go "bare minimum" but it would be nice to have something of a working idea as to what would prove deadly? Double, tripple? THAT is proving difficult to determine.
 
supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
You sound like you possibly have a little bit of tolerance to various things though that's impacting your particular situation? Or whatever was in the Blues wasn't what you thought?

Notwithstanding that, I don't want to go "bare minimum" but it would be nice to have something of a working idea as to what would prove deadly? Double, tripple? THAT is proving difficult to determine.
while it may not seem like it from my posts, i've only had opiate withdrawals once, maybe twice? in my life. idk why, i like them, a lot, but I've honestly never had a problem with a doing them for a second, then giving them up for weeks, sometimes months at a time. honestly it might just be because i'm too fucking broke lol, when it came to pick-me-ups, i used amphetamines, because $20 could last me a week or two lol, but still, not much of a problem quitting for extended periods of time.
haven't smoked weed since i was 16, besides a few one off tries where i immediately had a panic attack lol, and psychadelics are completely out of the question (schizoaffective)
that being said, at the time of my attempt, i had been stone cold sober for ~4 months prior, there were definitely no tolerances at play there.
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
while it may not seem like it from my posts, i've only had opiate withdrawals once, maybe twice? in my life. idk why, i like them, a lot, but I've honestly never had a problem with a doing them for a second, then giving them up for weeks, sometimes months at a time. honestly it might just be because i'm too fucking broke lol, when it came to pick-me-ups, i used amphetamines, because $20 could last me a week or two lol, but still, not much of a problem quitting for extended periods of time.
haven't smoked weed since i was 16, besides a few one off tries where i immediately had a panic attack lol, and psychadelics are completely out of the question (schizoaffective)
that being said, at the time of my attempt, i had been stone cold sober for ~4 months prior, there were definitely no tolerances at play there.
Then iffy products? It has to be. What other explanation is there? What you believed to be in those things actually wasn't.
 
supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
EDIT: most of my knowledge of psychopharmicology is entirely rooted in my own full alphabet of mental illnesses (schizoaffective bipolar type, bpd, ptsd, generalized anxiety disorder, major depression, and adhd lol), and i've had to learn the hard way a few too many times that doctors genuinely don't fully analyze how medications interact with each other, so i just do a little reading here and there, mostly about what pertains to me, and the mechanisms behind it, and overtime, i've just developed an overly specific (and for the most part, almost useless outside of very specific cases) knowledge of bodys and brains work.
it just so happens that opiates have fallen under that tiny sliver of knowledge (i break bones, A LOT lol)
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
What was supposed to be in those blue pills? Something extremely potent?
 
supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
Then iffy products? It has to be. What other explanation is there? What you believed to be in those things actually wasn't.
unfortunately not. the benzos came from my own doctor prescribed stash, and the blues were tested, once, in almost imperceptible amounts (just enough to feel it, and measure up to prior batches), something i have done literally every single time i picked up blues. they were close enough to the same strength as before that i couldn't tell a diference.
What was supposed to be in those blue pills? Something extremely potent?
around here they're sold as fentanyl (blue, m-30 print, speckled with blue and bits of green on close analysis, but look blue otherwise), but they've been tested occasionaly before for etidinazene, so idk.
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
unfortunately not. the benzos came from my own doctor prescribed stash, and the blues were tested, once, in almost imperceptible amounts (just enough to feel it, and measure up to prior batches), something i have done literally every single time i picked up blues. they were close enough to the same strength as before that i couldn't tell a diference.
Then you're a walking medical miracle or you still had some tolerance. Or you just somehow misjudged the potency and what you thought was in the blue tablets wasn't. Something was amiss somewhere.
Otherwise technically, you should be dead.
 
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supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
Then you're a walking medical miracle or you still had some tolerance. Technically, you should be dead
honestly, i know it's hard to believe, but my experience is a lot more common than you'd think among the veterans around here.
i'm not trying to tell this story as a way to convince you out of making your own decision about your own body, but rather, i'm trying to warn you that the human body can endure some insanely fucked up things and still come back.
if you want to save yourself the regret and shame, the extended mandatory psych ward stay, the prognosis of "opiate use disorder" immortalized in your medical charts (they will not prescribe you ANY scheduled medication for a LONG time), the potential of becoming a state ward, or kept under some other watchful eye, if you don't want to have to wake up afterwards with an overwhelming sense of failure, then don't bother risking it.
save up money, wait just a little bit longer, and make sure there's not a chance in hell of failure, because you DON'T want to end up like me, i can promise you that.
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
honestly, i know it's hard to believe, but my experience is a lot more common than you'd think among the veterans around here.
i'm not trying to tell this story as a way to convince you out of making your own decision about your own body, but rather, i'm trying to warn you that the human body can endure some insanely fucked up things and still come back.
if you want to save yourself the regret and shame, the extended mandatory psych ward stay, the prognosis of "opiate use disorder" immortalized in your medical charts (they will not prescribe you ANY scheduled medication for a LONG time), the potential of becoming a state ward, or kept under some other watchful eye, if you don't want to have to wake up afterwards with an overwhelming sense of failure, then don't bother risking it.
save up money, wait just a little bit longer, and make sure there's not a chance in hell of failure, because you DON'T want to end up like me, i can promise you that.
It isn't a question of saving my pennies. I have plenty. It's a question of just wanting to get it right first time. Hence looking for informed opinions.

How much Fentanyl was supposed to be in those blue tablets by the way?
 
supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
unknown tbh, and honestly still not even sure it was actually fentanyl. usually one pill would last me 2 or 3 days, would smoke (until heavy nod or blackout) 3ish times per night after work (at like 1:30, 2am lol, kitchens), if that says anything?
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
So blue pill. Don't know what's in it. Don't know how much is in it. But it usually does the trick recreationally. How does that sound to you? It's hardly scientific is it? *

That aside, could there perhaps be the slightest possibility you were sold a bunk batch somehow?

* I'm genuinely not trying to be rude. But you are telling me you know more than the medical establishment.
 
supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
i never did say that i know more, nor did i try to portray it that way, rather, i attested to discovering why certain drug combinations, prescribed to me, gave me akathesia, seratonin syndrome, or warning signs of potassium poisoning; concerns my doctor wouldn't take seriously until i actually dug around endless pubmed journals and studies until i could present with hard evidence of what was happening to me was, in fact, happening to me.

i don't know more than doctors. i have an extremely narrow focus on things i HAD to learn, and preemptively learned so that doctors would actually listen to me when i felt like i was dying.
ask me how say, literally any medication for the heart, lungs, kidneys, liver, gut, bowels, works, i have no fucking idea!
but anything i've been prescribed i had to study, hard, and you wanna know why? when your poor, and the waiting lists for pcps in your area accepting medicaid are literal years long, you go to a clinic.
at clinics, doctors have an extremely limitted amount of time to see, analyze, diagnose, and prescribe a patient, before they're whisked off to the next patient. day in, day out.
so tell me, do you think that you could provide someone with EVERYTHING they need about your field in 15 minute better than somebody, with literally infinite time on their hands, and an entire database containing nearly complete works on (your field) at their disposal?

so yeah, sorry i can't do the impoasible though, i really should've thought to analyse the biochemical properties of the molecule i have in mind, conduct an infinite amount of expiriments to determine what each molecule contained, then sorted each one by group, tested for for purity using gas chromotology, calculated the total values and then pieced it all back together, i'll remember next time!
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
i never did say that i know more, nor did i try to portray it that way, rather, i attested to discovering why certain drug combinations, prescribed to me, gave me akathesia, seratonin syndrome, or warning signs of potassium poisoning; concerns my doctor wouldn't take seriously until i actually dug around endless pubmed journals and studies until i could present with hard evidence of what was happening to me was, in fact, happening to me.

i don't know more than doctors. i have an extremely narrow focus on things i HAD to learn, and preemptively learned so that doctors would actually listen to me when i felt like i was dying.
ask me how say, literally any medication for the heart, lungs, kidneys, liver, gut, bowels, works, i have no fucking idea!
but anything i've been prescribed i had to study, hard, and you wanna know why? when your poor, and the waiting lists for pcps in your area accepting medicaid are literal years long, you go to a clinic.
at clinics, doctors have an extremely limitted amount of time to see, analyze, diagnose, and prescribe a patient, before they're whisked off to the next patient. day in, day out.
so tell me, do you think that you could provide someone with EVERYTHING they need about your field in 15 minute better than somebody, with literally infinite time on their hands, and an entire database containing nearly complete works on (your field) at their disposal?

so yeah, sorry i can't do the impoasible though, i really should've thought to analyse the biochemical properties of the molecule i have in mind, conduct an infinite amount of expiriments to determine what each molecule contained, then sorted each one by group, tested for for purity using gas chromotology, calculated the total values and then pieced it all back together, i'll remember next time!
I genuinely didn't mean to upset you. I'm exceedingly sorry if I did. And I do welcome your input. Its very much appreciated. I'm just a former academy so I always approach and analyse things scientifically. I can also be a bit brusk šŸ˜•
 
supergold#2

supergold#2

sapphic, suicidal, and stupid
Oct 20, 2024
77
i'm not mad at you for asking questions. i'm angry that you intentionally twisted my words around on me, and made me a characture you could belittle, when all i was trying to dowas help.
to me it feels like you're saying something along the lines of: "oh these gross creatures on this forum are all beneath me, i know that i'm right, i'll show them!"

we're all equals here. all that i've been trying to do was make sure that you don't end up where i'm at, and you spit it right back in my face.

if you're so certain, go ahead, do what you like. just know, i tried to warn you ahead of time.
 
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CatLvr

Enlightened
Aug 1, 2024
1,028
I had pretty much the same experience as @supergold#2 . More than enough doctor prescribed oxy, valium, lisinopril (figures it would help tank my BP) and something else that was a CNS depressant, all mixed with Jack Daniels, that I should not be here. And yet all that happened was a somewhat long "nap" and I woke up sitting on the sofa, with a screaming headache. Took me a week to get rid of the nausea (I never did vomit, though) and the headache. It's not worth it to try again. Also, like @supergold#2 although I take those "dangerous" opioids for pain I have rarely caught any kind of buzz from them and when I am not hurting bad, can do without them. No withdrawal ever and I have stopped and started them a bazillion times over the years. Go figure.
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
I had pretty much the same experience as @supergold#2 . More than enough doctor prescribed oxy, valium, lisinopril (figures it would help tank my BP) and something else that was a CNS depressant, all mixed with Jack Daniels, that I should not be here. And yet all that happened was a somewhat long "nap" and I woke up sitting on the sofa, with a screaming headache. Took me a week to get rid of the nausea (I never did vomit, though) and the headache. It's not worth it to try again. Also, like @supergold#2 although I take those "dangerous" opioids for pain I have rarely caught any kind of buzz from them and when I am not hurting bad, can do without them. No withdrawal ever and I have stopped and started them a bazillion times over the years. Go figure.
Do you feel you had a tolerance though?
i'm not mad at you for asking questions. i'm angry that you intentionally twisted my words around on me, and made me a characture you could belittle, when all i was trying to dowas help.
to me it feels like you're saying something along the lines of: "oh these gross creatures on this forum are all beneath me, i know that i'm right, i'll show them!"

we're all equals here. all that i've been trying to do was make sure that you don't end up where i'm at, and you spit it right back in my face.

if you're so certain, go ahead, do what you like. just know, i tried to warn you ahead of time.
No I wasnt saying that at all. I was saying perhaps (just perhaps there's maybe a possibility) what you thought was in those Blue tablets (that time) wasn't in fact in them. And I was trying to reason a possible explanation (which I put very poorly).
 
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CatLvr

Enlightened
Aug 1, 2024
1,028
Do you feel you had a tolerance though?

No I wasnt saying that at all. I was saying perhaps (just perhaps there's maybe a possibility) what you thought was in those Blue tablets (that time) wasn't in fact in them. And I was trying to reason a possible explanation (which I put very poorly).
Nope. No tolerance at all. I hadn't had any pain meds in 3 months (I was saving pills for what turned out to be an absolutely miserable attempt to crb).
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
Nope. No tolerance at all. I hadn't had any pain meds in 3 months (I was saving pills for what turned out to be an absolutely miserable attempt to crb).
Oxy is the big one there. How much of that did you have?
 
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CatLvr

Enlightened
Aug 1, 2024
1,028
Oxy is the big one there. How much of that did you have?
It's been a few years ... I'll have to think on that and see if I can remember what my dosages were back then. I do recall that not long after I tried doctors realized that valium and oxy together was creating a problem with OD deaths so they stopped prescribing them together. Same with muscle relaxers. Those and opioids seem to have the ability to make each work "better" than they do alone. Seems like I remember the 4th med being tizanidine.
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
It's been a few years ... I'll have to think on that and see if I can remember what my dosages were back then. I do recall that not long after I tried doctors realized that valium and oxy together was creating a problem with OD deaths so they stopped prescribing them together. Same with muscle relaxers. Those and opioids seem to have the ability to make each work "better" than they do alone. Seems like I remember the 4th med being tizanidine.
Valium is supposed to potentiate Oxy.
 
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CatLvr

Enlightened
Aug 1, 2024
1,028
Valium is supposed to potentiate Oxy.
All of the meds I tooks should have worked together with the whiskey to reduce my heart rate, blood pressure and breathing to levels so low I wouldn't have survived. Like I said, I guess I was lucky because there is absolutely no reason I should be here now.
Hmmm. The biggy I imagine is the oxycodone. I was trying to determine what a fatal dose of that was.
Not necessarily. Valium, tizanidine (both muscle relaxers), lisinopril (blood pressure med) and whiskey should have been more than enough all by themselves. I'm talking 90 days' worth of medication here, not 2 weeks. I got all the pills down, but not as much of the whiskey as I wanted. Regardless of that fact, I should NOT be here right now, muchless be here with no damage to myself at all. Well, except my stomach will not tolerate much on it now. I have to drink most of my calories over the course of the day. And God help me if I take more than a couple of pills at a time. Even with zofran I will have to really fight to keep from throwing them up. And I cannot even stand the smell of whiskey now.
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
All of the meds I tooks should have worked together with the whiskey to reduce my heart rate, blood pressure and breathing to levels so low I wouldn't have survived. Like I said, I guess I was lucky because there is absolutely no reason I should be here now.

Not necessarily. Valium, tizanidine (both muscle relaxers), lisinopril (blood pressure med) and whiskey should have been more than enough all by themselves. I'm talking 90 days' worth of medication here, not 2 weeks. I got all the pills down, but not as much of the whiskey as I wanted. Regardless of that fact, I should NOT be here right now, muchless be here with no damage to myself at all. Well, except my stomach will not tolerate much on it now. I have to drink most of my calories over the course of the day. And God help me if I take more than a couple of pills at a time. Even with zofran I will have to really fight to keep from throwing them up. And I cannot even stand the smell of whiskey now.
I'm not sure. My understanding is the biggies are the opiates and the other stuff just potentiates that. The other stuff in itself while unpleasant isn't the main thing. Others may know more than me but that's why they say (on here) why most ODs fail - because its difficult to do with prescription meds, unless you include a biggie (a large amount of an opiate for example).
 
kitchenwindow197

kitchenwindow197

Student
Sep 22, 2024
131
Depends on how tall you are and how much you weigh? In theory oxy seems like a great way to go, i personally loved the euphoric feeling until i had too much (maybe about 4/5pills) and it was literally the sickest ive ever felt- cant touch the stuff now. Chatgpt says 8-12 for mešŸ¤” (165cm 60kg) but i would add atleast 20 ontop of that. Id go 2.5mg/kg at minimum
 
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Richard Langford

Enlightened
Jan 10, 2025
1,019
Depends on how tall you are and how much you weigh? In theory oxy seems like a great way to go, i personally loved the euphoric feeling until i had too much (maybe about 4/5pills) and it was literally the sickest ive ever felt- cant touch the stuff now. Chatgpt says 8-12 for mešŸ¤” (165cm 60kg) but i would add atleast 20 ontop of that. Id go 2.5mg/kg at minimum
My understanding is (again after research) than many brands contain Naloxone now. Notwithstanding that, due to the nausea aspect they'd have to be taken another way.