Ketamine and opioids. I remember the first time i did ketamine, i pinched myself as hard as i could and didn't feel any pain. Opioids obviously help also, but i've always got the pain when i pinch really hard, even at heavy doses.
Btw, don't do it today, i'm not a prolifer but if you can't get any hardcore drugs, don't do it. Please.
But If you still decide to try, which i HARDLY recommend against, atleast aim at your neck, just at the sides of your adam's apple. That's where the major carotid arteries and jugular veins are. Google some anatomy pictures about those for reference