Hydroxylamine Sulfate

[Lilithium]

Hey y'all! I've been active on the threads trying to workshop the benzocaine method that Jisatsu came up with/may have ctb with. From the available literature, we know that it isn't benzocaine itself but it's metabolite, benzocaine hydroxylamine, that causes methemoglobinemia.

Having said that... this got me thinking that if the hydroxylamine metabolite is what causes the MetHb, would other hydroxylamine compounds potentially be viable methods?

Bit of a reach, but hydroxylamine sulfate came to mind as it causes methemoglobinemia that is intractable even with methylene blue, as well as sulfhemoglobinemia. It is potentially a more irritating compound than benzocaine as far as tissue goes, but it is also more readily absorbed both when ingested and through skin, and on paper it should induce MetHb and SulfHb fairly quickly. Crucially, you can purchase it relatively freely at least in the US.

There's very little literature on it but I will go fish for what exists in the morning. Admittedly I do not know for sure how much more or less irritating it is to mucous membranes compared to Benzocaine, SN, and KN. I believe it is rated at the same level as benzocaine for skin irritation, but it seems to be more reactive.

Just wanted to throw out the thought for the sake of science! but please do tell me if this is not at all viable, or if I'm missing something.

 

[piercedheart]

You'd need quite a lot of it for it to be effective, so there is a very big chance of failure as your body will fight tooth and nail to get rid of it. It will be extremely painful and unpleasant, and will damage your kidneys, leaving you even worse off than you started. I'd strongly recommend not to bother with it.

 

[Praestat_Mori]

These are only my thoughts.

If this was a reliable method it'd be mentioned in the PPH.

Any methods that rely heavily on metabolism are unreliable imo. Best example CTB by apple/apricot/bitter almonds seeds.