Odd this thread should come up when I was discussing this very subject with someone the other day. I am normally very introverted and nervous around strangers. Usually have to "put on a face" in situations where it's necessary, but it scares the hell out of me inside. However, LSD has an effect on me that makes me very outgoing and sociable. Not in a weird sorta way, more in how a "normal" outgoing person is, so, yeah. However, one can never know if this is effective or not until one tries. Also, I psych myself up to be in a positive mental space BEFORE I dose. I never take it if I cannot get it that mindset.