TheSource
From the Divine we came, to the Divine we return.
- Sep 25, 2023
- 123
It seems to be a huge misconception that immediate-release (short-acting) opioids are more lethal than extended-release (long-acting/controlled-release).
Though they are more likely to be abused, that's because there is more satisfaction from the immediate high. Comparing the lethality, though, ER opioids are actually more dangerous.
Of course, I never make claims without citing my sources, so here is the information from credible sources. I encourage you to read the full texts, as context helps provide a broader understanding of information.
The Abuse Potential Difference Between Immediate-Acting and Extended-Release Opioids:
www.chapmanrehab.com
"because they deliver the opioid medication over a longer period of time, there is an increased risk of overdose and death."
Controlled-release opioids cause harm and should be avoided in management of postoperative pain in opioid naïve patients:
"Sedation and respiratory depression are more common with the inappropriate use of controlled-release opioids."
Prescription Opioid Duration of Action and the Risk of Unintentional Overdose Among Patients Receiving Opioid Therapy:
jamanetwork.com
"After adjustment for age, sex, opioid dose, and other clinical characteristics, patients receiving long-acting opioids had a significantly higher rate of overdose injury than did those receiving short-acting opioids."
PLEASE DON'T HESITATE TO COMMENT WITH MORE SOURCES OF INFORMATION IF YOU FIND ANY, WHETHER PROVING OR DISPROVING THIS CLAIM.
Though they are more likely to be abused, that's because there is more satisfaction from the immediate high. Comparing the lethality, though, ER opioids are actually more dangerous.
Of course, I never make claims without citing my sources, so here is the information from credible sources. I encourage you to read the full texts, as context helps provide a broader understanding of information.
The Abuse Potential Difference Between Immediate-Acting and Extended-Release Opioids:
The Abuse Potential Difference Between Immediate-Acting and Extended-Release Opioids
www.chapmanrehab.com
Controlled-release opioids cause harm and should be avoided in management of postoperative pain in opioid naïve patients:
"Sedation and respiratory depression are more common with the inappropriate use of controlled-release opioids."
Prescription Opioid Duration of Action and the Risk of Unintentional Overdose Among Patients Receiving Opioid Therapy:
Opioid Duration of Action and Risk of Overdose
This propensity score–adjusted cohort study finds that the risk of unintentional opioid overdose injury is related to the prescribed opioid’s duration of action. Accompanying editorial by Katz.
jamanetwork.com
PLEASE DON'T HESITATE TO COMMENT WITH MORE SOURCES OF INFORMATION IF YOU FIND ANY, WHETHER PROVING OR DISPROVING THIS CLAIM.
