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Carrot2775

New Member
Mar 31, 2026
2
Hello everyone ๐Ÿ‘‹

Does anyone have any insight into crushing pills before CTB?

I've got a bit of a mixture of drugs and I am uncertain about the particular order and other details. My whole plan is multimodal in the sense that it targets different systems of the body (respiration, blood sugar, asphyxiation, cardiac). It may seem overly determined, however, that is purposeful to ensure death. The idea is that each individual assault on the different systems of the body should be enough to CTB independently. The chances of surviving not just one but multiple systematic assaults should ensure near 100% success.

Anti Nausea Medication - Ondansetron (Zofran)
I'm planning on taking taking 25 4mg tablets crushed (100mg total) of ondansetron (Zofran) 40 minutes before CTB to minimise/eliminate possible vomiting from the bitter taste and harshness of the lethal drug cocktail. Ideally, I would also have a dopamine anti-nausea medication like metoclopramide, prochlorperazine, domperidone, and haloperidol, however they are difficult to acquire where I am.

Can anyone see any issues or any possible negative implication of this?

I've also got 262.5mg of zopiclone (hypnotic sleeping pill) that I'm gonna take too. I was thinking of taking this T-40 min before CTB as well.
What are your thoughts?


Lethal Cocktail
I'm not sure if I can post the specifics of the drugs that I'm gonna take but it includes these classes:
  • opiates
  • benzos
  • insulin
  • TCA's
  • SSRI's
  • antidiarrheal
My question is would crushing and mixing the pills together then drinking then deactivate them or interact in a way that would make them less toxic when absorbed?

Let me know what you think. I really apreciate any and all feedback, ideas, thoughts, etc.
 
5karlet

5karlet

๐Ÿ›Œ
Feb 13, 2024
114
shi if i was you id snort the benzos and percs. that should set you straight. dont take my word for it tho
 
Last edited:
unluckysadness

unluckysadness

Enlightened
Jul 9, 2025
1,599
The only thing I know with crushing benzos is the fact they are more effective when they are crushed. In the PPH 2025, they recommend to crush benzos and mix it with a little bit water for these reasons.
 
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Carrot2775

New Member
Mar 31, 2026
2
shi if i was you id snort the benzos and percs. that should set you straight. dont take my word for it tho
Yeah for sure. I just don't know if I could do so much all at once tbh even though I don't have a massive amount. Thanks for the response. Appreciate it
The only thing I know with crushing benzos is the fact they are more effective when they are crushed. In the PPH 2025, they recommend to crush benzos and mix it with a little bit water for these reasons.
I've discovered this too! Crushing the pills increases the surface area of them allowing them to be absorbed more rapidly by the body. I'm planning on fast a couple days before to which should help increase absorption further. Thanks for the infor
 
H

hdead

Wizard
Jun 2, 2026
605
From what I've read on here snorting benzos is not a great idea due to the amount of filler.

Also, taking that amount of zopiclone 40 minutes ahead of time will put you to sleep before you can manage to drink your cocktail, so maybe be cautious with that.

Fasting is not necessary for a few days. Actually, with opioids, it's better to have a little light food with them to counteract the nausea and help with gastric emptying even though the D blockers will help with that as well.

Depending on what specific sedatives and opiates you're looking to use; check out grapefruit juice too!

My 2ct. Gbye and Gluck!
 
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nayomi

nayomi

only the truth will save us all
Jul 19, 2026
223
i know that opiods is not recommended because it make it more likly to puke.

just follow normal sn tutorial instead of doing all of this crap
 
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H

hdead

Wizard
Jun 2, 2026
605
i know that opiods is not recommended because it make it more likly to puke.

just follow normal sn tutorial instead of doing all of this crap
And you think that drinking an inorganic salt, i.e. straight up checmical, will not make you puke it up? Meto/oda will help with the opioid puking risk just as much as with SN.

I am definitly trying the OD route before trying SN because I'll be asleep in 5 minutes. Just create a little space where I can lie down on my back and if I happen to vomit I'll just aspirate. Going out Hendrix style, just without the Seconal.
 
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nayomi

nayomi

only the truth will save us all
Jul 19, 2026
223
And you think that drinking an inorganic salt, i.e. straight up checmical, will not make you puke it up? Meto/oda will help with the opioid puking risk just as much as with SN.

I am definitly trying the OD route before trying SN because I'll be asleep in 5 minutes. Just create a little space where I can lie down on my back and if I happen to vomit I'll just aspirate. Going out Hendrix style, just without the Seconal.
if you take and vomiting meds probably not
 
H

hdead

Wizard
Jun 2, 2026
605
if you take and vomiting meds probably not
Got my meto ready to go. I'm thinking of also dosing 800mg+ seroquel for additional sedation and dopamine blocking and maybe some ginger.
 
hevnsfall

hevnsfall

Cat mom
Jul 18, 2026
86
But why also insulin and anti diahreea meds ?
 
Serena 2026

Serena 2026

Experienced
Jan 15, 2026
213
From what I've read on here snorting benzos is not a great idea due to the amount of filler.

Also, taking that amount of zopiclone 40 minutes ahead of time will put you to sleep before you can manage to drink your cocktail, so maybe be cautious with that.

Fasting is not necessary for a few days. Actually, with opioids, it's better to have a little light food with them to counteract the nausea and help with gastric emptying even though the D blockers will help with that as well.

Depending on what specific sedatives and opiates you're looking to use; check out grapefruit juice too!

My 2ct. Gbye and Gluck!
Hello, your answer was excellent, and I agree with your opinion... I just had a question about the grapefruit juice: could you clarify if it's meant to improve the medication's absorption? C an it be replaced with orange juice? ๐Ÿ™
 
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DeathSweetDeath

DeathSweetDeath

Visionary
Nov 12, 2025
2,231
Hello, your answer was excellent, and I agree with your opinion... I just had a question about the grapefruit juice: could you clarify if it's meant to improve the medication's absorption? C an it be replaced with orange juice? ๐Ÿ™
I'm not them, but no, many meds come with a warning not to take them with grapefruit juice specifically. It causes them to enter the bloodstream at dangerously high levels.
 
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Serena 2026

Serena 2026

Experienced
Jan 15, 2026
213
From what I've read on here snorting benzos is not a great idea due to the amount of filler.

Also, taking that amount of zopiclone 40 minutes ahead of time will put you to sleep before you can manage to drink your cocktail, so maybe be cautious with that.

Fasting is not necessary for a few days. Actually, with opioids, it's better to have a little light food with them to counteract the nausea and help with gastric emptying even though the D blockers will help with that as well.

Depending on what specific sedatives and opiates you're looking to use; check out grapefruit juice too!

My 2ct. Gbye and Gluck!
Hi, your answer was great and I agree with your opinion... I just had a question about the grapefruit juice, could you clarify if it's to improve the absorption of the medication? Can it be replaced with orange juice? ๐Ÿ™„๐Ÿ™
I'm not them, but no, many meds come with a warning not to take them with grapefruit juice specifically. It causes them to enter the bloodstream at dangerously high levels.
I apologizeโ€”I still get a bit confused around hereโ€”but thank you for replying! ๐Ÿ™‚๐Ÿ™
 
H

hdead

Wizard
Jun 2, 2026
605
Hi, your answer was great and I agree with your opinion... I just had a question about the grapefruit juice, could you clarify if it's to improve the absorption of the medication? Can it be replaced with orange juice? ๐Ÿ™„๐Ÿ™
Hey, the grapefruit specifically breaks down (inhibits) the CYP3A4 enzyme in the liver and makes it harder for your body to break down some drugs. Only some though! It will result in a higher blood plasma concentration of the drug because the liver won't metabolize it as good.

It's worth investigating before acting on it. For example; oxycodone is broken down primarily by CYP3A4 but morphine is not!

In short; no, you cannot replace grapefruit juice with orange juice.
 
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Serena 2026

Serena 2026

Experienced
Jan 15, 2026
213
Hey, the grapefruit specifically breaks down (inhibits) the CYP3A4 enzyme in the liver and makes it harder for your body to break down some drugs. Only some though! It will result in a higher blood plasma concentration of the drug because the liver won't metabolize it as good.

It's worth investigating before acting on it. For example; oxycodone is broken down primarily by CYP3A4 but morphine is not!

In short; no, you cannot replace grapefruit juice with orange juice.
So, I read somewhere on this site that grapefruit potentiates Nembutal (which will be my protocol soon), but I'd like to be sure. I actually downloaded Sasu's book on methods to read it, but it's entirely in English and I can't translate itโ€”I can't copy and paste the text into a translator... Besides that, where I live, it's impossible to find the actual grapefruit or pure grapefruit juice... I only found grapefruit liqueur, and I don't know if that would be suitable... what do you think?
Ahh, thanks for replying anyway!! ๐Ÿ™‹๐Ÿปโ€โ™€๏ธ๐Ÿ™
 

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