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seekingrelease22

Member
Feb 28, 2024
96
I have 60 of the 500mg depakote would this be enough to kill me?
 
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Praestat_Mori

Mori praestat, quam haec pati!
May 21, 2023
8,865
What's depakote?

Here's info about ODing:


 
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sanitystruggle

Specialist
Mar 12, 2024
334
Valproate: it's generally fairly safe with severe toxicity only occuring at doses of 400mg-1000mg/kg or more and it's fairly readily treatable if you were found:


Very high doses cause multi-organ toxicity so there's the possibility of lasting damage if you recover.
What's depakote?
 
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Praestat_Mori

Mori praestat, quam haec pati!
May 21, 2023
8,865
Valproate: it's generally fairly safe with severe toxicity only occuring at doses of 400mg-1000mg/kg or more and it's fairly readily treatable if you were found:


Very high doses cause multi-organ toxicity so there's the possibility of lasting damage if you recover.
Quote from the link:
------------------------------
RISK ASSESSMENT

Severity of toxicity is related to the dosage ingested:

<200mg/kg: nil to minor effects, i.e. mild drowsiness
200 – 400mg/kg: moderate toxicity, i.e. CNS depression
400 — 1000 mg/kg: severe toxicity, i.e. Coma
>1g/kg: potentially life threatening, i.e. profound coma, multi-organ toxicity including hypotension, metabolic (lactic) acidosis, cerebral oedema, biochemical abnormalities, bone marrow suppression
------------------------------


At an avg body weight of 75kg you would have to ingest min 75g of this medicine. That's a lot and therefore the method is unreliable imo.
 
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