It is Soviet drug and any info or research is hard to find, even in Russian .
It's a phenobarbital prodrug.
A metabolite of an anticonvulsant drug Benzonal was isolated from the guinea pig blood serum and identified by high performance liquid chromatography (HPLC). By using HPLC as well as ultraviolet-, infrared- and mass-spectrometry it was established that in the guinea pig intestine Benzonal undergoes alkaline hydrolysis with the formation of phenobarbital. The native Benzonal in the guinea pig blood serum was not found.
LD50 is not clear. It's for mice and always varies .
(1)
(2)
The amount of phenobarbital in it, wondering if anybody knows.
70%, according to molecular weight .
Russian research states (note the bad translation):
Rapidly absorbed from the intestines, is metabolized by phenobarbital (is thus prodrug) and then oxidized mikrosomalnoy system tsitohroma P450. Creates high concentrations in the brain, liver and kidneys. Penetrates gistogematicheskie through barriers and breast milk. Effect develops through 20-60 minutes after solid reception. T1/2 is 3-4 days. Excreted kidneys as unchanged, and in the form of metabolites.
Had proper research been done, we could have known how much is actually converted to phentobarbital, and be more accurate. We have to count on LD50 estimates .
It converts to
phenobarb and not
pentobarb, as PPH emphasizes:
Nembutal is the commercial or trade name for the barbiturate whose chemical name is pentobarbital . This drug is different to another barbiturate called phenobarbital . Phenobarbital is a slow - acting drug , used predominantly as an anti - convulsant to stabilise people suffering from epilepsy . While phenobarb can be lethal in overdose , it has a much slower action than Nembutal and is not an ideal method for self - deliverance . These two barbiturates should not be confused
As
@calendulo noted phenobarb (as opposed to N/nembutal/pento) can be used to ctb -- with other sedatives as part of a cocktail .
See their attached PDF in the post above :)
PPH gives phenobarb (and hence the aforementioned benzobarb) as part of its
cocktail or
standalone:
The final drug is the barbiturate , Phenobarbital. This slow acting barbiturate is still prescribed as an anti - convulsant and can also be used as a solo end of life agent ( see reference to Phenobarb in the ' Taking Nembutal ' Chapter ) . The drug shown was sourced over the Internet . The illustration shows 200 x 3Gmg tablets , making a total of 6 gm of the ding . Three or more bottles would be required for the necessary 20gm .
However as a standalone PPH states
10g should kill , though slowly , so one is advised to use benzo (or other strong sleeping pills: knockout before):
Phenobarb is a different drug . In its usual form , phenobarb is a slow - acting anti - convulsant , prescribed when there is a risk of convulsions ( eg . brain trauma etc ) .
Some people will have access to phenobarb , either from their own doctor or from overseas pharmaceutical suppliers . A drink of lOgm ( ~ 250 of the white
30mg tablets shown in Fig 19.6 ) crushed and mixed with water will be lethal .
Note : There is no rapid loss of consciousness , as in the case of Nembutal . The time to death using phenobarbitone can be several hours . If one isfound before death resuscitation is very possible .
Phenobarb can , however , be made more effective by raising the pH of the solution of the crushed tablets . This is done using Sodium Carbonate to convert the Phenobarbetal to the more readily absorbed sodium phenobarbital . If available , lgm of Dilantin can be added to this drink with good eifect .
To reduce the time from taking the drink to loss of consciousness , a second drink made from a benzodiazepam sleeping drug
is recommended ( eg , Serapax , oxazepam or Mogadon , nitrazepam ) . Again , alcohol can be an effective supplement .
Phenobarb is also mentioned here on the forum:
Pheno has a lethal dose of 6 grms.
you'd have to take 7.2 grams
(However as mentioned PPH recommends 20g as part of a 3- or 4-drug cocktail; or 10g as a standalone? weird ...)
--What cocktail is similar to N?
--10 grams phenobarbital/ 2 grams oxy-fent mix/20 grams xanax/alcohol
https://sanctioned-suicide.net/threads/fenobarbital.35295
https://sanctioned-suicide.net/threads/phenobarbital-v-n.25255/
https://sanctioned-suicide.net/threads/do-you-trust-in-phenobarbital.36267/
Phenobarbital LD is 162mg/kg and Benzobarbital LD is 345-982mg/kg , so multiply the required phenobarbital dosage by 2 to 6. Benzobarbital is mostly (70%) phenobarbital , so if most of it is actually converted to phenobarbital (as everything suggests) , I'd say the x2 multiplier is realistic ..
TLDR:
- Benzobarbital is a Phenobarbital prodrug .
- Phenobarbital recommended lethal dosage varies (see above) , ranges from 6g to 20g.
- Equivalent for bezonal/benzobarbital would range from 12g to 40g (or 36g to 120g ; I'd go for lower x2 estimate) .
- PPH states 10g Phenobarbital as fatal -- so 20g Benzobarbital is required.
- It is viable as ctb , though long-acting (several hours) -- follow guides (do not confuse with pentobarbital).
clever-geek.github.io
So it appears to be benzoic acid and phenobarbital.
www.emcdda.europa.eu
