No, definitely not over this paranoia.
It was a 50 state split. Biden won't have the power to do it. Furthermore, GOP nominees now hold the Court by a 6-3 margin, easily the biggest achievement Trump possibly could have realized. Beyond that, with the cyclical nature of politics being what they are, the Democrats will lose both seats of Congress in two years.
Also, if they manage to piss off just one Senator of their own party (say, Joe Manchin), they will lose control of the Senate (as actually happened when Vermont's Jim Jeffords left the Republicans to become an Independent caucusing with the Democrats in May, 2001).
Biden is not coming in strong like Obama did in 2009. The 117th Congress is an extremely tenuous majority for the Democrats, not like the 111th Congress was for the newly elected Obama, and the Democrats are a badly fractured party between the establishment liberals and vocal progressive insurgency.
What the incoming administration really needs to do is expedite the distribution of the vaccine ASAP. An extended lockdown would be political suicide for the Democrats. They could wind up losing enough Senate seats in 2022 to set up a 60 seat majority for the GOP in 2024.
Democrats have to continually remind themselves that Trump just received the second largest number of popular votes in American history. The most important thing they can do right know is try to rush through a second impeachment and hope against hope for a conviction and removal of Trump from office before January 20th, so he won't be eligible to run again in 2024. (That itself will be a tall order. They will need a 2/3rds vote to convict with a Senate which is evenly split between the parties. Republican Senators facing reelection bids in the next four years don't want to risk their seats by voting to convict the most popular Republican President in history, and Trump just GAINED 11 million votes from 2016.)