Zofran maximum dose?

[TerminallyAlive]

I can get as much as I want to take before drinking my poison of choice. I will also be trying to get meto, but idk yet.

My question is: how much Zofran can/should I take? Is there a limit before it just won't do any more good or will cause limiting side effects like meto? Can it be combined with meto?

I vomit rather easily, so I want to do everything I can to prevent that.

Thanks.

(I accidentally posted this with the wrong drug name before).

 

[Aap]

24mg is administered before the most nauseating chemotherapeutic agents. While some will rush to warn of serotonin syndrome, this is exceptionally rare.

 

[TerminallyAlive]

Thanks. Is there any reason not to double or triple that?

 

[Aap]

I wouldn't go much higher. While the oral bioavailability is lower for oral than IV, above this dosage is seen some strange side effects related to low blood pressure or serotonin syndrome.