@Chinaski , @Rex ,
I have never experienced nausea on a low or moderate dose of a relatively weak opiate. High doses of powerful opiates are different of course, but there is usually more going on when one takes those.
A quote 'Results. A number of mechanisms by which opioids produce nausea and vomiting have been identified. These involve both central and peripheral sites including the vomiting center, chemoreceptor trigger zones, cerebral cortex, and the vestibular apparatus of the brain, as well as the GI tract itself'. Would ondantseron be effective for that ? Of course one doesn't want to load up on too many drugs.
Nausea can mean different things ? Like, the feeling of sickness and the urge to vomit. Meto only helps with the vomiting, right ?