Why can't you overdose on Quetiapine?

[Oh so tired]

Ive tried, it doesn't work Sadly.You become very slow and drunkish, to be honest when I took the OD I kinda enjoyed it because for the first time in ages I was away from reality.

I felt the same, it was a break from all the rubbish going on in my head as well as a physical break as I had an amazing deep sleep! Did you need medical attention?

 

[Walilamdzi]

Ive tried, it doesn't work Sadly.You become very slow and drunkish, to be honest when I took the OD I kinda enjoyed it because for the first time in ages I was away from reality.

I felt the same, it was a break from all the rubbish going on in my head as well as a physical break as I had an amazing deep sleep! Did you need medical attention?

What kind of dosages were you guys taking?

Even from taking minor overdosages of this I've felt like I was having a mini seizure and things and I've taken random dosages after tapering off it sometimes when I couldn't sleep and then not woken up for the entire day so I wonder what will happen.

 

[Oh so tired]

What kind of dosages were you guys taking?

Even from taking minor overdosages of this I've felt like I was having a mini seizure and things and I've taken random dosages after tapering off it sometimes when I couldn't sleep and then not woken up for the entire day so I wonder what will happen.

I took 12 quetiapine (25mg) as well as 12 Clonazepam (500microgram) and a few citalopram. Knocked me out pretty quickly and I needed help with my breathing.

 

[Walilamdzi]

I took 12 quetiapine (25mg) as well as 12 Clonazepam (500microgram) and a few citalopram. Knocked me out pretty quickly and I needed help with my breathing.

See 12 x 25mg is less than what I am supposed to be on daily (something which I find crazy) but given that I have stockpiled like 2 months supply of 500mg a day, maybe it would be more likely to do something more serious?

Sounds pretty unpleasant, I'm sorry to hear you had this experience.

 

[Oh so tired]

See 12 x 25mg is less than what I am supposed to be on daily (something which I find crazy) but given that I have stockpiled like 2 months supply of 500mg a day, maybe it would be more likely to do something more serious?

Sounds pretty unpleasant, I'm sorry to hear you had this experience.
[/QUOTE
Really?! My daily dose is 75mg.
Probably worth mentioning I'm tiny (just over 6stone) as I have an eating disorder, everything has more effect on me than other people!

 

[Deathcabforugly]

See 12 x 25mg is less than what I am supposed to be on daily (something which I find crazy) but given that I have stockpiled like 2 months supply of 500mg a day, maybe it would be more likely to do something more serious?

Sounds pretty unpleasant, I'm sorry to hear you had this experience.

I take a shitload of the stuff daily and took a months worth and it didn't kill me

 

[Oh so tired]

See 12 x 25mg is less than what I am supposed to be on daily (something which I find crazy) but given that I have stockpiled like 2 months supply of 500mg a day, maybe it would be more likely to do something more serious?

Sounds pretty unpleasant, I'm sorry to hear you had this experience.

Really?! My daily dose is 75mg.
Probably worth mentioning I'm tiny (just over 6stone) as I have an eating disorder, everything has more effect on me than other people!

 

[Walilamdzi]

Really?! My daily dose is 75mg.
Probably worth mentioning I'm tiny (just over 6stone) as I have an eating disorder, everything has more effect on me than other people!

Yeah and even that megadose is less than what they decided to put me on the first time I was hospitalised, at 19 they put me on a massive dose of 800mg. Is there anything that's helped you with your eating disorder, if you don't mind me asking? My friend is losing weight at a rapid rate and has a lot of rules around what they eat, if something doesn't change it will probably become anorexia - I just wondered if you have any idea for suggestions I can make?

I take a shitload of the stuff daily and took a months worth and it didn't kill me

I find that it makes me catatonic unless I'm in a totally manic stage so it kind of works at first, maybe, then it stops me from functioning.

 

[Oh so tired]

Yeah and even that megadose is less than what they decided to put me on the first time I was hospitalised, at 19 they put me on a massive dose of 800mg. Is there anything that's helped you with your eating disorder, if you don't mind me asking? My friend is losing weight at a rapid rate and has a lot of rules around what they eat, if something doesn't change it will probably become anorexia - I just wondered if you have any idea for suggestions I can make?

I'm afraid I'm losing the battle with the anorexia at the moment so not sure what help i can be. Is your friend able to acknowledge that there's a problem and would she/he be willing to accept help? The earlier the better in terms of intervention as when eating behaviours set in they are so hard to get out of. Eating little and often can help, I'm currently *supposed* to be adding in tiny amounts like a few spoonfuls of yogurt and a small glass of fruit juice and I manage this on good days. Being completely nonjudgmental and a listening ear is the best help of all

 

[Walilamdzi]

I'm afraid I'm losing the battle with the anorexia at the moment so not sure what help i can be. Is your friend able to acknowledge that there's a problem and would she/he be willing to accept help? The earlier the better in terms of intervention as when eating behaviours set in they are so hard to get out of. Eating little and often can help, I'm currently *supposed* to be adding in tiny amounts like a few spoonfuls of yogurt and a small glass of fruit juice and I manage this on good days. Being completely nonjudgmental and a listening ear is the best help of all

She has acknowledged a that she's made up quite a lot of different rules about food but struggling to add anything to her diet I think. I'm really worried. Was there something specific which caused yours to develop?

 

[Nobbo]

I felt the same, it was a break from all the rubbish going on in my head as well as a physical break as I had an amazing deep sleep! Did you need medical attention?

I went to hospital yes, not necessarily cause the OD would kill me but more just to monitor me and my heart because apparently because of the OD there was some irregularities in my heart rate . How bout you?

 

[Oh so tired]

She has acknowledged a that she's made up quite a lot of different rules about food but struggling to add anything to her diet I think. I'm really worried. Was there something specific which caused yours to develop?

I'll send you a pm x

 

[Walilamdzi]

I'll send you a pm x

Hang on I'll just change my settings - should work now x

 

[Oh so tired]

I went to hospital yes, not necessarily cause the OD would kill me but more just to monitor me and my heart because apparently because of the OD there was some irregularities in my heart rate . How bout you?

Yeah, I was found unconscious so was taken to A&E by ambulance, I had difficulty breathing and some heart irregularities too. Wasn't kept in for long though. Very fuzzy memories of the whole thing.

 

[Moreofthesamepain]

You're more likely to end up with serotonin syndrome than ctb.

 

[BorderlineSuixide]

What did they do in the hospital?

they pumped my stomach and i was fine

 

[Walilamdzi]

You're more likely to end up with serotonin syndrome than ctb.

Doesn't quetiapine reduce serotonin? Or am I confusing that with dopamine?

 

[Walilamdzi]

Someone in another thread said their best friend died of an OD of 60mg. I have another month's supply now, not sure how much exactly but maybe enough to be fatal? Would you crush the pills up for an OD attempt?

 

[autumnal]

The pharmacological explanation is no doubt very complicated, but just know that is is practically impossible to fatally overdose on, as per the journal articles people have already shared. From a practical standpoint, it's also sensible for modern psychiatric medications to aim to be non-fatal in overdose, by virtue of the fact they are used on a population who are often suicidal.

 

[Alyatl]

I was prescribed this stupid fuckin pill (I could go on a long ass rant of why I hate it) after being diagnosed with borderline, and they knew of my past attempts to OD on pills, and this shit is insanely hard to OD on, especially since people with schizophrenia have to take a fuck ton of it daily for the antipsychotic effect to kick in. I've tried, and then they found out, and only give me a weeks worth of pills at a time, it's really embarrassing lol.

My friend came over and I told him I was about to take my meds, I decided to chug the whole thing (god knows how much was in there, but it was the initial release stuff and that shit is brutal) and I passed out on him pretty quick, was out like a light, and when I was barely conscious I couldn't feel anything, he was slapping my face to try and keep me present. Felt like a horse being shot with a tranquilizer dart, that's all.

Bottom line, bad pill that serves me hardly any purpose except for me to feel nothing and sleep. Can't even ctb with it, useless I tell you!

 

[Walilamdzi]

The pharmacological explanation is no doubt very complicated, but just know that is is practically impossible to fatally overdose on, as per the journal articles people have already shared. From a practical standpoint, it's also sensible for modern psychiatric medications to aim to be non-fatal in overdose, by virtue of the fact they are used on a population who are often suicidal.

This is so frustrating.

I was prescribed this stupid fuckin pill (I could go on a long ass rant of why I hate it) after being diagnosed with borderline, and they knew of my past attempts to OD on pills, and this shit is insanely hard to OD on, especially since people with schizophrenia have to take a fuck ton of it daily for the antipsychotic effect to kick in. I've tried, and then they found out, and only give me a weeks worth of pills at a time, it's really embarrassing lol.

My friend came over and I told him I was about to take my meds, I decided to chug the whole thing (god knows how much was in there, but it was the initial release stuff and that shit is brutal) and I passed out on him pretty quick, was out like a light, and when I was barely conscious I couldn't feel anything, he was slapping my face to try and keep me present. Felt like a horse being shot with a tranquilizer dart, that's all.

Bottom line, bad pill that serves me hardly any purpose except for me to feel nothing and sleep. Can't even ctb with it, useless I tell you!

How much did you take?

 

[Alyatl]

This is so frustrating.

How much did you take?

If I did the math correctly it was about 2g? I'm pretty tiny (106lbs) so I'm surprised it didn't do much to me. I was prescribed 150mg daily, had multiple weeks worth of supply. It just knocked me out, I vomited after and felt like a zombie for days but nothing more than that.

 

[Walilamdzi]

If I did the math correctly it was about 2g? I'm pretty tiny (106lbs) so I'm surprised it didn't do much to me. I was prescribed 150mg daily, had multiple weeks worth of supply. It just knocked me out, I vomited after and felt like a zombie for days but nothing more than that.

I can't believe they expect me to take 500mg per day... it's a stupid dose.

 

[Alyatl]

I can't believe they expect me to take 500mg per day... it's a stupid dose.

How do you feel when you take it? It feels like a chemical sledgehammer to my brain. 500mg is absolutely nuts.

 

[Szs33]

You can overdose it but you wont die. I once took 40 pills and woke up laying down on the floor.

 

[Walilamdzi]

How do you feel when you take it? It feels like a chemical sledgehammer to my brain. 500mg is absolutely nuts.

I don't, the psychiatrist/mental health haven't found out yet but I wager they may section me when they do. They've put me on 800mg before too. I don't need it, the times I have had psychotic features were to do with cannabis, but they are acting as though I have psychotic features usually which I don't and didn't ask me anything contextual...

It doesn't sound like you should have been prescribed this either.

 

[SpottedPanda]

I was once given double the dose of Quetiapine in hospital, and it honestly felt like chemical torture. I found it hard to breathe, my throat was closing up, my veins popped out, my eyes went bloodshot, and my heart was pounding. Would definitely not advise attempting a overdose on Quetiapine

 

[Walilamdzi]

I was once given double the dose of Quetiapine in hospital, and it honestly felt like chemical torture. I found it hard to breathe, my throat was closing up, my veins popped out, my eyes went bloodshot, and my heart was pounding. Would definitely not advise attempting a overdose on Quetiapine

That sounds dreadful. What dose had you meant to have?


I have found some overdoses related to Q:
"On the day of the overdose, Mr. A was discovered to be comatose, presumably a few hours after ingestion of the quetiapine, and in acute respiratory distress. Resuscitation efforts by paramedics were unsuccessful. An autopsy revealed cardiomegaly, with left ventricular hypertrophy and bilateral pulmonary congestion. Further testing revealed quetiapine and nicotine in his urine and a negative immunoassay screening test for his other medications. Mr. A's serum quetiapine level was 18,300 ng/ml (steady-state expected range: 100–1,000 ng/ml). Quetiapine was also detected in his gastric contents. Calculation of pill ingestion from pharmacy records of his last refill, based on an assumption of regular medication compliance, estimated his overdose at approximately 10,800 mg of quetiapine."

https://www.latimes.com/local/lanow/la-me-jail-death-lawsuit-medication-20190228-story.html


"In case #1, the concentrations of quetiapine found were 7.20 mg/L (19 micromol/L) in blood and 0.93 mg/L (2.4 micromol/L) in vitreous fluid. In case #2, the concentrations of quetiapine found were 16 mg/L in blood (42 micromol/L), 120 mg/kg (310 micromol/kg) in liver, and 1.8 mg/L (4.6 micromol/L) in vitreous fluid. In case #3, the concentrations of quetiapine found in femoral blood was 5.90 mg/L (15 micromol/L). In all cases, drugs in addition to quetiapine were detected, but in cases #1 and #2, the cause of death was considered to be a quetiapine overdose and the other drugs were not considered to be contributory. Case #3 was considered a mixed drug overdose."

 

[SpottedPanda]

That sounds dreadful. What dose had you meant to have?

If I remember correctly I was meant to take 250 mg, but was given 500mg

 

[Inner_dialogue]

I have tried a few times and all that happens is I get knocked out for a few hours and feel dazed for days! My heart rate goes higher and I go dizzy, can't really remember much after that tbh. Think the most I've taken is 5000mg and I've thrown in some paracetemol and ADs and still nothing. I've given up using it as a ctb method, maybe I do use to need more....